LEC 1 Flashcards
Enzymes are said to be [?] , which can ionize as be either acid or base.
AMPHOTERIC
Activators are non-protein organic biochemical cofactors. (True or
False)
FALSE
A substance derived from a transformed substrate.
PRODUCT
The primary structure of a protein is maintained by what type of bond?
PEPTIDE BOND
This is an enzyme without a cofactor.
APOENZYME
Haloenzyme is the combination of
COENZYME AND ENZYME
Site on the enzyme where a substrate binds to.
ACTIVE SITE
The tertiary structure of the enzyme is maintained by what type of bond?
COVALENT DISULFIDE BOND
Transferase enzymes give information about damage to what organ?
LIVER
Enumerate the three groups of hydrolases.
ESTERASE
PEPTIDASE
GLUCOSIDASE
[Lyases are assayed in disorders of what tissue?
SKELETAL MUSCLE TISSUE
What are the 2 older names of Oxidoreductase?
DEHYDROGENASE
OXIDASE
Oxidoreductase enzymes are tested for the investigation of disorders associated with what two organs?
HEART
LIVER
Classification of enzyme responsible for the conversion of 1 isomer to another.
ISOMERASES
Classification of enzyme responsible for bond formation.
LIGASES
The 2nd digit in the systematic name of enzymes denotes what?
SUB-CLASS
This is a structurally different form of the enzyme that catalyzes the same reaction
ISOENZYMES
In first-order kinetics, the substrate concentration is fixed. (true or false)
FALSE
Zero-order kinetics depends on enzyme concentration (true or false)
TRUE
This pertains to the reaction rate being doubled for every 10C increase in temperature.
Q10 VALUE
In terms of pH, this is the point at which the reaction rate is greatest.
OPTIMUM PH
The International Unit is expressed in terms of:
u/L
Reactions catalyzed by enzymes are frequently reversible (true or false)
TRUE
In the reaction catalyzed by oxidoreductases, donors of electrons are known as:
OXIDANT
Classification of enzymes that splits molecules with water as part of the reaction.
HYDROLASES
Reactions catalvzed by Isomerase enzvmes ate irreversible. (true or false)
FALSE
What enzyme naming of enzyme describes the nature of the reaction catalyzed?
SYSTEMATIC CLASSIFICATION
What enzyme naming makes use of acronyms and abbreviations?
TRIVIAL NAME
Enumerate the two theories related to enzyme-substrate combination.
LOCK AND KEY THEORY
INDUCED FIT THEORY
shows the relationship of the reaction velocity to the substrate concentration
MICHAELIS - MENTEN CURVE
Thermal inactivation of enzymes happens to start at what
temperature?
50 deg C
Enumerate 2 chemical substances which may cause inhibition of enzyme activity.
STRONG SALT CONCENTRATION
