LEC 1

Question 1

Enzymes are said to be [?] , which can ionize as be either acid or base.

Answer 1

AMPHOTERIC

Question 2

Activators are non-protein organic biochemical cofactors. (True or
False)

Answer 2

FALSE

Question 3

A substance derived from a transformed substrate.

Answer 3

PRODUCT

Question 4

The primary structure of a protein is maintained by what type of bond?

Answer 4

PEPTIDE BOND

Question 5

This is an enzyme without a cofactor.

Answer 5

APOENZYME

Question 6

Haloenzyme is the combination of

Answer 6

COENZYME AND ENZYME

Question 7

Site on the enzyme where a substrate binds to.

Answer 7

ACTIVE SITE

Question 8

The tertiary structure of the enzyme is maintained by what type of bond?

Answer 8

COVALENT DISULFIDE BOND

Question 9

Transferase enzymes give information about damage to what organ?

Answer 9

LIVER

Question 10

Enumerate the three groups of hydrolases.

Answer 10

ESTERASE
PEPTIDASE
GLUCOSIDASE

Question 11

[Lyases are assayed in disorders of what tissue?

Answer 11

SKELETAL MUSCLE TISSUE

Question 12

What are the 2 older names of Oxidoreductase?

Answer 12

DEHYDROGENASE

OXIDASE

Question 13

Oxidoreductase enzymes are tested for the investigation of disorders associated with what two organs?

Answer 13

HEART
LIVER

Question 14

Classification of enzyme responsible for the conversion of 1 isomer to another.

Answer 14

ISOMERASES

Question 15

Classification of enzyme responsible for bond formation.

Answer 15

LIGASES

Question 16

The 2nd digit in the systematic name of enzymes denotes what?

Answer 16

SUB-CLASS

Question 17

This is a structurally different form of the enzyme that catalyzes the same reaction

Answer 17

ISOENZYMES

Question 18

In first-order kinetics, the substrate concentration is fixed. (true or false)

Answer 18

FALSE

Question 19

Zero-order kinetics depends on enzyme concentration (true or false)

Answer 19

TRUE

Question 20

This pertains to the reaction rate being doubled for every 10C increase in temperature.

Answer 20

Q10 VALUE

Question 21

In terms of pH, this is the point at which the reaction rate is greatest.

Answer 21

OPTIMUM PH

Question 22

The International Unit is expressed in terms of:

Answer 22

u/L

Question 23

Reactions catalyzed by enzymes are frequently reversible (true or false)

Answer 23

TRUE

Question 24

In the reaction catalyzed by oxidoreductases, donors of electrons are known as:

Answer 24

OXIDANT

Question 25

Classification of enzymes that splits molecules with water as part of the reaction.

Answer 25

HYDROLASES

Question 26

Reactions catalvzed by Isomerase enzvmes ate irreversible. (true or false)

Answer 26

FALSE

Question 27

What enzyme naming of enzyme describes the nature of the reaction catalyzed?

Answer 27

SYSTEMATIC CLASSIFICATION

Question 28

What enzyme naming makes use of acronyms and abbreviations?

Answer 28

TRIVIAL NAME

Question 29

Enumerate the two theories related to enzyme-substrate combination.

Answer 29

LOCK AND KEY THEORY
INDUCED FIT THEORY

Question 30

shows the relationship of the reaction velocity to the substrate concentration

Answer 30

MICHAELIS - MENTEN CURVE

Question 31

Thermal inactivation of enzymes happens to start at what
temperature?

Answer 31

50 deg C

Question 32

Enumerate 2 chemical substances which may cause inhibition of enzyme activity.

Answer 32

STRONG SALT CONCENTRATION