Learning, Memory Flashcards
what structure is responsible for primitive emotional responses
hypothalamus
what antagonizes the frontal cortex?
hypothalamus–negatively influences frontal cortex’s control over emotions
what antagoznies the hypothalamus?
frontal cortex
what area is important for the making and appreciation of art as emotions?
prefrontal cortex
role of the prefrontal cortex
makes sure memory, emotion, strategy–the executive fxns of brain–run smoothly.
extinction of bad memories
where are emotional memories stored
amygdala, hippocampus
explain how synaptic plasticity works
AMPA R responsible for basal Na+ influx and synaptic transmission
however, when there’s high activation/depolarization, Mg2+ on NMDA R leaves, so now the NMDA R opens up to allow Ca2+ influx to postsynpatic neuron. Ca2+ activates CaMKII to bring AMPA R in postsy neur to the synapse
Long term potentiation
an induction used so that when the same presynaptic stimulus occurs, it results in higher reponses for a longer time compared to baseline synaptic transmission
What is long term potentiation useful for
as a model for learning and memory
what is used to study learning and memory at the behavioral level?
Morris water maze
fear conditioning
what structure is responsible for the fact that when cued with a tone that was present in a painful situation (this time without the painful shock), a mouse will stop moving?
amygdala
what structure is responsible for remembering the context of painful situations?
hippocampus and amygdala
CaMKII
enzyme that phosphorylates, and contributes to long term potentiation
Calcineurin
phophatase that contributes to long term depression
what does long term potentiation do
enhances synaptic strength