Learning And Memory Flashcards
what is learning mediated by?
structural changes in the synapses
what does LTP stand for?
Long Term Potentiation
what is LTP?
a long-lasting increase in synaptic efficacy following high-frequency stimulation of afferent fibers
what does LTP do in the hippocampus?
it enhances the ability of a stimulus to produce cell firing=learning
What do NMDA and AMPA do?
they are receptors of glutamate and mediate excitatory synaptic transmission by gating the flow of calcium and sodium ions into the cell
What is NMDA selective to?
calcium ions
what is AMPA selective to?
sodium ions
what is AMPA selective to?
sodium ions
what is the Key Hebbian principle?
“cells which fire together wire together, cells which fire apart wire apart”
what is Long term depression (LTD)?
decrease in synaptic strength due to low fequency stimulation of a neuron
what does LTD result in
forgetting previous learning
what is explicit memory?
information that you’re trying to remember is stored here
what is the medial temporal lobe - HM Case?
removal of the hippocampus and surrounding cortex caused him to forget the events of his daily life as fast as they occur
what is implicit memory?
memory of actions
examples of implict memory include..
priming, mirror-drawing task