Last Phys Lectures Flashcards
what causes primary hyposecretion
abnormality in the gland itself
what causes secondary hyposecretion
deficiency of the gland’s tropic hormone
what does down regulation of hormone receptors result in?
decreased sensitivity to hormone
what is hormone permissiveness
one hormone enhancing the target cell’s responsiveness to another hormone
are chondrocytes a component of bone?
no
what hormone is permissive to growth hormone
thyroid hormone
what is the main constituent of colloid in the thyroid gland
thyroglobulin
what attaches iodide to tyrosine
thyroid peroxidase
what can inhibit TSH and thyroid hormone secretion
stress
what would a person without PTH die from
hypocalcemia respiratory spasm
How does PTH increase plasma calcium concentration
by enhancing kidney activation of vitamin D
what does calcitonin do to Ca2+ mobilization
decreases CA2+ mobilization from bone
what is the active form of Vitamin D
calcitriol
what does aldosterone do
promotes Na reabsorption and K excretion
what is a symptom of aldosterone hypersecretion
hypokalemia
what is a metabolic effect of cortisol
stimulates hepatic gluconeogenesis
what does cortisol have permissive action for
catecholamines
how is cortisol regulated
by the hypothalamic-pituitary-adrenal cortex axis
what does DHEA do in females
contributes to pubic and axillary hair growth
what causes primary adrenocortical insufficiency (Addison’s disease)
autoimmune destruction of adrenal cortex
what is a symptom of aldosterone deficiency
hypotension
T/F: epinephrine and norepinephrine bind to different types of receptors
true
what does somatostatin inhibit
digestive system, insulin and glucagon secretion
what is not an effect of insulin on carbohydrate metabolism
stimulating gluconeogenesis