Last min SBA Flashcards

1
Q

You see a 48-year-old woman in clinic following a cholecystectomy 6 months ago. She complains that since the operation she has experienced chronic diarrhoea which seems to float in the toilet.

What would be the best medication to offer to help with these symptoms?

Bismuth salts
11%
Cholestyramine
46%
Creon
30%
Loperamide
10%
Rehydration salts
You see a 48-year-old woman in clinic following a cholecystectomy 6 months ago. She complains that since the operation she has experienced chronic diarrhoea which seems to float in the toilet.

What would be the best medication to offer to help with these symptoms?

Bismuth salts

Cholestyramine

Creon

Loperamide

Rehydration salts

A

Cholestyramine

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2
Q

A 74-year-old Caucasian man presents for a management review of his heart failure. He was previously classified as NYHA class II but now describes worsening symptoms and significant breathlessness when climbing the stairs. His medications include the maximum dose of ramipril, spironolactone, and bisoprolol.

An echocardiogram is performed revealing an ejection fraction of 31%. An ECG shows a right bundle branch block with a QRS width of 164 milliseconds. It is decided that this patient should undergo an interventional procedure to improve symptoms.

What is the most appropriate management?

Cardiac catheter ablation

Cardiac resynchronisation therapy (CRT)

Coronary angiography

Implantable cardiac defibrillator (ICD)

Primary percutaneous coronary intervention

A

Cardiac resynchronisation therapy (CRT)

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3
Q

While covering an emergency, you evaluate a 30-year-old man brought in by his partner after having a sudden seizure attack. The patient has a history of epilepsy that has been well-controlled.

Recently, he has adopted new healthy habits following his father’s heart attack, including quitting smoking, exercising to lose weight, and taking multivitamins. However, the patient informs you that he has also started taking aspirin, left over from his wife, in the hope of reducing his risk.

What of the patient’s new habits or medications is most likely to have a significant influence on his epilepsy control?

Taking aspirin

Taking bupropion

Taking multivitamins

Taking nicotine replacement therapy

Taking varenicline

A

Taking bupropion

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4
Q

An 18 month old boy is brought to the emergency room by his parents. He was found in bed with a nappy filled with dark red blood. He is haemodynamically unstable and requires a blood transfusion. Prior to this episode he was well with no prior medical history.
What is the most likely cause?

A.	Necrotising enterocolitis	
B.	Anal fissure	
C.	Oesophageal varices	
D.	Meckels diverticulum	
E.	Crohns disease
A

Meckels diverticulum is the number one cause of painless massive GI bleeding requiring a transfusion in children between the ages of 1 and 2 years.

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5
Q

A 32-year-old pregnant female is due to have an induction of labour at 38 weeks gestation due to cholestasis of pregnancy. She undergoes a pelvic examination and a Bishop’s score of 4 is calculated.
What treatment is most suitable?

A.	Vaginal prostaglandin (PGE2)	
B.	Syntocinon	
C.	Caesarian section	
D.	No treatment required	
E.	Syntometrine
A

Vaginal PGE2 or oral misoprostol is the preferred method of induction of labour if the Bishop score is <6

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6
Q

Addison’s patient with intercurrent illness →

A

double the glucocorticoids, keep fludrocortisone dose the same

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7
Q

A 65-year-old lady has recently had a colonoscopy and been found to have a malignant tumour in the most distal portion of the rectum, involving the anal sphincter.
Which of the following surgical procedures would be the best option for her?

A.	Hartmann's procedure	
B.	Left hemicolectomy	
C.	Abdominoperineal (AP) resection	
D.	Transverse colectomy	
E.	Anterior resection
A

Rectal cancer on the anal verge → Abdomino-perineal excision of rectum

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8
Q

A 61-year-old man is admitted to the surgical assessment unit with renal colic. He has had pain for the past four days, but worst in the last 24 hours. His renal function is normal and an ultrasound scan demonstrates a dilated right ureter and right hydronephrosis. A CT of his urinary tract demonstrates a right ureteric stone.
What is the most appropriate first line management for this man?

A.	Flexible cystoscopy and stone retrieval	
B.	Extra-corporeal shockwave lithotripsy (ESWL)	
C.	Conservative management
D.	Open stone retrieval	
E.	Nephrostomy
A

Nephrostomy

Acute upper urinary tract obstruction is managed with nephrostomy

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9
Q

A 53-year-old man with alcoholic liver cirrhosis is seen in the hepatology outpatient clinic. He is slightly tremulous and visibly jaundiced. Since his last follow-up appointment, he has developed worsening ascites.
Which of the following blood tests, when compared to his previous, will best represent changes in his liver function?

A.	Alanine transaminase (ALT)	
B.	Alkaline phosphatase (ALP)	
C.	Aspartate transaminase (AST)	
D.	Gamma-glutamyl transferase (GGT)	
E.	Prothrombin time (PT)
A

Liver enzymes are a poor way to look at liver function - they are usually low in end-stage cirrhosis whereas coagulation and albumin are better measures

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10
Q

A 40-year-old male attends the GP surgery requesting further information regarding vasectomy for contraception. He and his wife have 4 children, and are both confident that they do not want any further children.
What advice do you give him with regards to vasectomy as a form of contraception?

A.	Vasectomy is an immediate form of contraception	
B.	Sterilisation is confirmed following clear semen analysis	
C.	Sterilisation is established following 30 ejaculations	
D.	Sterilisation is established after 4 months	
E.	Sterilisation is established after 6 months
A

Sterilisation is confirmed following clear semen analysis

Vasectomy isn’t an immediate form of contraception; semen analysis must be performed and azoospermia confirmed before used as contraception

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11
Q

A 35-year-old female G1 P0 presents to her local hospital at 36 weeks pregnancy. She is carrying a singleton fetus. She is in the early stages of labour (cervical dilation = 2cm). The amniotic sac has not yet ruptured. An abdominal exam reveals the fetus is presenting in transverse lie. There have been no complications in the pregnancy to date. There is no evidence of abnormal bleeding.
What is the most suitable next step?

A.	Perform an emergency cesarean section in the next 30 minutes	
B.	Perform an elective cesarean section	
C.	Attempt vaginal delivery	
D.	Attempt forceps delivery	
E.	Perform external cephalic version
A

. Perform external cephalic version

You can attempt external cephalic version for a transverse lie if the amniotic sac has not ruptured

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12
Q

Baby born after being in breech

What further DDH screening, if any, is required in this case?

A.	Ultrasound screening is required within 72 hours of birth	
B.	Bilateral hip x-rays should be taken 3 weeks after birth	
C.	Repeat Ortolani and Barlow tests at 4 weeks after birth	
D.	Ultrasound screening is required 6 weeks after birth	
E.	No further screening is required
A

Ultrasound screening is required 6 weeks after birth

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13
Q

A 40-year-old male presents to his GP as he has had long-standing fatigue. The also reports some joint pain, mostly in his hands. He denies any weight loss, fevers, or night sweats. He reports that his father had something similar and he thinks he used to have to give blood regularly.

On examination, the joints in his hands do not appear inflamed or hot to touch, but his skin has a grey / brown appearance.

You decide to order some blood tests.

Given the likely diagnosis, what are the iron studies most likely to show?
TIBC = total iron binding capacity

A.	Raised transferrin saturation, low ferritin, raised TIBC	
B.	Low transferrin saturation, low ferritin, low TIBC	
C.	Low transferrin saturation, raised ferritin, low TIBC	
D.	Raised transferrin saturation, raised ferritin, raised TIBC	
E.	Raised transferrin saturation, raised ferritin, low TIBC	

Raised transferrin saturation and ferritin, with low TIBC is the characteristic iron study profile in haemochromatosis

A

Raised transferrin saturation, raised ferritin, low TIBC

Haemochromatosis causes excess iron accumulation.

Transferrin is the main protein that iron binds to for transport in the blood. Haemochromatosis causes increased iron, so more will be available to bind to transferrin so the saturation (percentage of transferrin bound to iron) is increased.

Ferritin is the intracellular storage form of iron, with a small amount found in blood, so increased body iron raises this value.

TIBC is a measure of available binding sites on transferrin. If there is a lot of iron, these sites are taken up so there is less capacity to bind more, hence TIBC is low in iron overload.

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14
Q

A 62-year-old publican is admitted with ascites. Following investigations he is diagnosed with decompensated cirrhosis and is to undergo paracentesis to remove a large amount of fluid from his abdomen. An albumin infusion is started.
What is the main benefit of prescribing albumin when treating large volume ascites’?

A.	Reduce postparacentesis circulatory dysfunction	
B.	Minimise seizure risk	
C.	Reduce incidence of recurrence	
D.	Maintain eGFR	
E.	Minimise infection risk
A

Large-volume paracentesis for the treatment of ascites requires albumin ‘cover’. Evidence suggests this reduces paracentesis-induced circulatory dysfunction and mortality

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15
Q

You are on the night on-call team, and a 76-year-old woman on one of your wards has developed increasing confusion. She is wandering around the ward asking for her husband and is shouting at staff and other patients. She was admitted this morning with a high fever and a one-week history of a productive, purulent cough. She also has a history of Parkinson’s disease.

Nursing staff have been unable to calm her and she has now started to throw objects and hit staff members. The nurses have however been able to give you the following obs:

Temperature 37.8°C
Heart Rate 105 bpm
BP 138/78 mmHg
SaO2 95% on room air
Blood glucose 5 mmol/L
Which of the following is the most appropriate treatment?

A.	Immediate release carbidopa-levodopa	
B.	Olanzapine	
C.	Lorazepam	
D.	Amitriptyline	
E.	Haloperidol
A

Lorazepam

Typical antipsychotics should be avoided in delirious patients with a background of Parkinson’s disease

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16
Q

A 55-year-old woman presents to the emergency department with a sudden onset of central chest pain while she was at rest. The pain was not relieved by her glyceryl trinitrate spray. She has a past history of angina and hypertension. ECG and cardiac biomarkers were positive for an ST-elevation myocardial infarction (STEMI).

A few minutes later, she complained of worsening shortness of breath. On examination, her pulse was weak and thready. Her jugular venous pressure is increased. On chest auscultation, there was a new systolic murmur. Her pulse rate was 130 beats per minute and blood pressure was 80/55 mmHg. There were no new acute changes to the ECG.
Which of the following is the most likely diagnosis?

A.	Arrhythmia	
B.	Aortic regurgitation	
C.	Aortic stenosis	
D.	Mitral regurgitation	
E.	Left ventricular aneurysm
A

mitral regurgitation

Rupture of the papillary muscle due to a myocardial infarction → acute mitral regurgitation → widespread systolic murmur, hypotension, pulmonary oedema

17
Q

An 76-year-old lady has spent a week on the ward following a surgically-repaired neck of femur fracture. Serial blood tests reveal:

Date Platelet Count
10/10 260 * 109/l
14/10 90 * 109/l
18/10 23 * 109/l

On 19/10 she develops a large DVT in her right leg and the consultant believes this series of events may be drug-induced.
Which of the following is the most likely cause of this presentation?

A.	Aspirin	
B.	Low molecular weight heparin	
C.	Clopidogrel	
D.	Metformin	
E.	Oxycodone
A

Heparin induced thrombocytopenia is a prothrombotic state

18
Q

You are called to the postnatal ward as part of the neonatal team to review an infant born 8 hours ago who has suddenly turned blue and has an increased work of breathing. There is no grunting and he is not tachypnoeic. There is no murmur on examination.

A chest x-ray has been done which shows obvious cardiomegaly but it has not yet been reported. The ward team have already tried giving oxygen but this has not improved the breathing.
What is the most appropriate initial management?

A.	Alprostadil	
B.	Furosemide	
C.	Ibuprofen	
D.	Insert naso-gastric tube for feeding	
E.	Oxygen	

Maintenance of the ductus arteriosus with prostaglandins is the initial management for duct dependent congenital heart disease

A
19
Q

A 55-year-old lady has undergone a wide local excision and sentinel lymph node biopsy for breast cancer. The histology report shows a completely excised 1.3cm grade 1 invasive ductal carcinoma. The sentinel node contained no evidence of metastatic disease. The tumour is oestrogen receptor negative.
What is the next course of action?

A.	Monitor in clinic with annual review and mammography	
B.	Arrange radiotherapy	
C.	Arranged combined chemoradiotherapy	
D.	Arrange chemotherapy	
E.	Prescribe antioestrogen
A

arrange radiotherapy

Whole breast radiotherapy is recommended after a woman has had a wide-local excision as this may reduce the risk of recurrence by around two-thirds

20
Q
A
20
Q
A
21
Q
A
22
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A
22
Q

moa of open angle glaucma med

A

ABC reduce production of aqueous humour
- alpha agonists, beta blockers, carbonic anhydrase

M + P increase uveoscleral outflow
-miotics, prostaglandin analogues

23
Q

glasgow for pancreas

A

P - PaO2 <8kPa

A - Age >55-years-old

N - Neutrophilia: WCC >15x10(9)/L

C - Calcium <2 mmol/L

R - Renal function: Urea >16 mmol/L

E - Enzymes: LDH >600iu/L; AST >200iu/L

A - Albumin <32g/L (serum)

S - Sugar: blood glucose >10 mmol/L

24
Q

management of simple otitis media

A

topical gentamicin + hydrocortisone drops

25
Q

A 42-year-old woman with a past medical history of rheumatoid arthritis presents to her GP with a 2-week history of increased inflammation and pain in the wrist of her right hand. She feels more generally fatigued and has noticed the drop in her energy as she has taken to having an afternoon nap. She is currently treated with sulfasalazine.

On examination, the wrist is swollen but is not erythematous or hot. The GP takes some bloods which show the following:

What is the most appropriate initial management?

A.	Empirical antibiotics IV	
B.	Hydrocortisone IV	
C.	Increase sulfasalazine dose PO	
D.	Methotrexate PO	
E.	Methylprednisolone IM
A

Intramuscular steroids such as methylprednisolone are used to manage the acute flares of rheumatoid arthritis

26
Q

ovarian reserve

A

anti-mullerian

27
Q

Patients who take a staggered paracetamol overdose should receive treatment with

A

acetylcysteine

28
Q

Start alendronate in patients

A

> = 75 years following a fragility fracture, without waiting for a DEXA scan

29
Q

A 24-year-old woman attend with her partner having tried to conceive for 2 years. She has a regular 35 day cycle and her last menstrual period was 3 weeks ago. A recent STI screen was unremarkable. As part of the initial investigations for subfertility, she has progesterone checked to confirm ovulation.
On which day of her menstrual cycle should she have the blood test for progesterone?

A.	Day 1-5
B.	Day 14	
C.	Day 21	
D.	Day 28	
E.	Day 35	

.

A

To confirm ovulation: Take the serum progesterone level 7 days prior to the expected next period

This woman has a 35 day cycle so 35 - 7 days = day 28. Therefore day 28 is the day that a serum progesterone should be taken