LAST FRKN ONE

Question 1

AVP (vassopressin)

Answer 1

“my second gen vape pen makes my mouth dry but at least i don’t pee myself”
MOA: binds to V2 receptors incrases aquaporin on cell membranes
Tx : hypopituitarism
AE: dry mouth hyponatremia
also Tx noctornia

Question 2

Growth hormone

Answer 2

“growing pains make my muscles and joints sore”
synthetic GH
Tx: hypopituitarism
AE: edema and jt muscle pain

Question 3

Spironolactone

Answer 3

“My mini sprite made me hyper”
mineralocorticoid
Tx: hyperaldosteronism
Potassium sparing diuretic that can be used as a NON SELECTIVE ALDOSTERONE RECEPTOR

Question 4

Eplerenone

Answer 4

tx: hyperaldosteronism

SELECTIVE FOR ALDOSTERONE

Question 5

Fludicortisone

Answer 5

I am so thirsty i could use some fluid

tx: hypoaldosteronism

Question 6

Hydrocortisone

Answer 6

“I buy my hydros from addy on the court”
addison’s disease
short term: hyperglycemia
long term: increase risk of bone fracture

Question 7

Testosterone

Answer 7

Andy likes to test his cardio
Androgen deficiency
Increased risk of MI, STROKE, CV death
increase risk of hepatic tox

Question 8

oxybutynin

Answer 8

Benny was a pro at taking oxy
benign prostatic hypertrophy
Anticholinergic

Question 9

Calcium

Answer 9

hypoparathyroidism and osteoporosis

AE: hypercalcemia, hypercalciuria

Question 10

vitamin D

Answer 10

osteoporosis

taken with Calcium usually

Question 11

levothyroxine (synthroid)

Answer 11

Sydney & Tito loves to monitor their hungry hippos
Hypothyroidism
synthetic T3, T4
well tolerated
monitor levels NTI
take on empty stomach

Question 12

methimazole

Answer 12

Meth makes me hyper and makes my stomach itch
hyperthyroidism
blocks T3 and T4
GI issues, arthralgia

Question 13

metformin (glucophage)

Answer 13

I sat first row in seat B12 at the big mets game and ate 2 times
biguanide
type II diabetes
Inhibs production of glucose
LOW risk of Hypoglycemia
Vitamin B12 deficiency
FIRST LINE for type II

Question 14

Glipizide

Answer 14

I ate 2 glizzies and a beer that tasted like sulfur
type II diabetes
binds sulfonylurea receptor in pancreas
HYPERGLYCEMIA (especially in elderly)
BEERS
Take before breakfast (30mins)

Question 15

Levadopa-carbidopa (Sinement)

Answer 15

levi parks his car with motor disturbances at the BBB to get some dope
PD
Lev: precursor dopamine
Carb: stops breakdown of lev
AE: motor disturbances
1st line

Question 16

ropinirole (Requip)

Answer 16

we stopped rolling dope in the park and passed out
PD
antagonises dopamine receptors
OH

Question 17

interferon B

Answer 17

Ms. psycho interfered with my flu
MS
FLU LIKE SYMPTOMS
monitor neuropsychiatric changes

Question 18

Glatiramer acetate

Answer 18

Vladamir missed injection
MS
reduce autoimmune response
injection site
PML

Question 19

fingolimod

Answer 19

Brady can’t see and his finger is inflamed
MS
blocks release of lymphocytes - decrease inflammation
Muscular edema
monitor bradycardia

Question 20

dimethyl fumarate

Answer 20

The fumes from my meth made my stomach and liver hurt
MS
use PO BID
GI and flushing

Question 21

monoclonal antibodies

Answer 21

After my mono infusion, I got an MRI and an infection
MS
decreasing exacerbations, slow progression
infusion related reactions
PML

Question 22

baclofen

Answer 22

my low back insert made me spasm and my CV depressed
direct acting agent
MS
Treats spacity for MS
inhib effect on alpha motor neuron
cardiac/resp depr, muscle weakness, sedation
if abruptly stopped major side effects
pump refills every 3 months

Question 23

donepezil (Aricept)

Answer 23

Don forgot to do his 12 oz curls
Alzheimer's
only modest improvements
inhib ACh
SLUDGE DUMBELLS

Question 24

escitalopram (Lexapro)

Answer 24

Lex was a sad pro nazi 
SSRI
antidepressant
inhib reuptake of 5-HT
less anticholinergic and CV
sedation, bleed hyponatremia

Question 25

citalopram (Celexa)

Answer 25

I selcect special services to hit me
SSRI
antidepressant
inhib reuptake of 5-HT
less anticholinergic and CV
sedation, bleed hyponatremia

Question 26

duloxetine (Cymbalta)

Answer 26

HTing cybals NEar my head gave me a headache
SNRI
antidepressant
inhib uptake of 5-HT and NE
dry mouth, sweating insomnia, tremor
1st line if neuropathic pain or fibromyalgia

Question 27

Vanlafaxine (Effexor)

Answer 27

Norm and Tami have fibromyalgia affecting their mouth so they can’t bang it out
SNRI
antidepressant
inhib uptake of 5-HT and NE
dry mouth, sweating insomnia, tremor
1st line if neuropathic pain or fibromyalgia

Question 28

bupropion (Wellburtin)

Answer 28

Well Burton was sad and NEDA eat more
atypical
antidepressant
Inhib NE and DA
decreased appetite, significant insomnia, risk of seizure

Question 29

cyclobenzaprine (Flexeril)

Answer 29

My flexible friend cycled to get rid of spazzing
muscle relaxant
central acting antispasmodic
onset 1 hr peak 2-8 hrs lasts for 12-24

Question 30

alprazolam (Xanax)

Answer 30

I only pop a xanny in my benz when im nervous in
benzo
anxiety
binds to BZD
sedation, ataxia
prn use preffered

Question 31

buspirone (buspar)

Answer 31

I took the bus 3 weeks ago, im worried i missed my stop
anxiety
dizziness sedative
no risk of buse
3 weeks to see effect

Question 32

quetipine (seroquel)

Answer 32

SGA
schizophrenia
block D2 receptors more affinity for 5-HT2
EPS possible, METABOLIC DYSFUNCTION

Question 33

lithium

Answer 33

Bipolar
manage acute manic episode may take 5-10 days for response
POLYURIA, POLYDIPSIA LITH TOX
L- levels
I- increased uniation
T- thirsty, tremors
H - hair thinning, hypothyroidism
I - interactions 
U - upset stomach
M - muscle weakness
S - Skin effects

Question 34

mthylphenidate (concerta, ritalin)

Answer 34

the meth concert blocked my great DANE from coming and it hurt my heart
ADHD
block DA and NE reuptake
weight loss, disphoria, CV RISK AND ABUSE POTENTIAL
monitor vital signs

Question 35

mixed amphetamine salts (adderall)

Answer 35

block DA and NE reuptake
weight loss, disphoria, CV RISK AND ABUSE POTENTIAL
monitor vital signs

Question 36

atomexotine (Strattera)

Answer 36

I selected to go to the suicide boyz conert in the streets
ADHD
SELECTIVE NE
suicide risk 
2-4 weeks full benefit 6-12 weeks

Question 37

tzanidine

Answer 37

Taz used to be a spaz but now he's sleepy
alpha 2 agonist
spasticity
drowsiness sedation
2-3times a day 
start at bedtime to titrate slowly
selectively bind to a2 receptors

Question 38

botulinum toxin (botox)

Answer 38

blocks ACh into NM jx

rare cases of spread to distal tissues for hours/weeks after injection