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Final Pharm > LAST FRKN ONE > Flashcards

LAST FRKN ONE Flashcards

1
Q

AVP (vassopressin)

A

“my second gen vape pen makes my mouth dry but at least i don’t pee myself”
MOA: binds to V2 receptors incrases aquaporin on cell membranes
Tx : hypopituitarism
AE: dry mouth hyponatremia
also Tx noctornia

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2
Q

Growth hormone

A

“growing pains make my muscles and joints sore”
synthetic GH
Tx: hypopituitarism
AE: edema and jt muscle pain

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3
Q

Spironolactone

A

“My mini sprite made me hyper”
mineralocorticoid
Tx: hyperaldosteronism
Potassium sparing diuretic that can be used as a NON SELECTIVE ALDOSTERONE RECEPTOR

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4
Q

Eplerenone

A

tx: hyperaldosteronism

SELECTIVE FOR ALDOSTERONE

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5
Q

Fludicortisone

A

I am so thirsty i could use some fluid

tx: hypoaldosteronism

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6
Q

Hydrocortisone

A

“I buy my hydros from addy on the court”
addison’s disease
short term: hyperglycemia
long term: increase risk of bone fracture

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7
Q

Testosterone

A

Andy likes to test his cardio
Androgen deficiency
Increased risk of MI, STROKE, CV death
increase risk of hepatic tox

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8
Q

oxybutynin

A

Benny was a pro at taking oxy
benign prostatic hypertrophy
Anticholinergic

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9
Q

Calcium

A

hypoparathyroidism and osteoporosis

AE: hypercalcemia, hypercalciuria

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10
Q

vitamin D

A

osteoporosis

taken with Calcium usually

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11
Q

levothyroxine (synthroid)

A 
Sydney & Tito loves to monitor their hungry hippos
Hypothyroidism
synthetic T3, T4
well tolerated
monitor levels NTI
take on empty stomach
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12
Q

methimazole

A

Meth makes me hyper and makes my stomach itch
hyperthyroidism
blocks T3 and T4
GI issues, arthralgia

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13
Q

metformin (glucophage)

A 
I sat first row in seat B12 at the big mets game and ate 2 times
biguanide
type II diabetes
Inhibs production of glucose
LOW risk of Hypoglycemia
Vitamin B12 deficiency
FIRST LINE for type II
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14
Q

Glipizide

A 
I ate 2 glizzies and a beer that tasted like sulfur
type II diabetes
binds sulfonylurea receptor in pancreas
HYPERGLYCEMIA (especially in elderly)
BEERS
Take before breakfast (30mins)
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15
Q

Levadopa-carbidopa (Sinement)

A 
levi parks his car with motor disturbances at the BBB to get some dope
PD
Lev: precursor dopamine
Carb: stops breakdown of lev
AE: motor disturbances
1st line
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16
Q

ropinirole (Requip)

A

we stopped rolling dope in the park and passed out
PD
antagonises dopamine receptors
OH

17
Q

interferon B

A

Ms. psycho interfered with my flu
MS
FLU LIKE SYMPTOMS
monitor neuropsychiatric changes

18
Q

Glatiramer acetate

A 
Vladamir missed injection
MS
reduce autoimmune response
injection site
PML
19
Q

fingolimod

A

Brady can’t see and his finger is inflamed
MS
blocks release of lymphocytes - decrease inflammation
Muscular edema
monitor bradycardia

20
Q

dimethyl fumarate

A

The fumes from my meth made my stomach and liver hurt
MS
use PO BID
GI and flushing

21
Q

monoclonal antibodies

A

After my mono infusion, I got an MRI and an infection
MS
decreasing exacerbations, slow progression
infusion related reactions
PML

22
Q

baclofen

A 
my low back insert made me spasm and my CV depressed
direct acting agent
MS
Treats spacity for MS
inhib effect on alpha motor neuron
cardiac/resp depr, muscle weakness, sedation
if abruptly stopped major side effects
pump refills every 3 months
23
Q

donepezil (Aricept)

A 
Don forgot to do his 12 oz curls
Alzheimer's
only modest improvements
inhib ACh
SLUDGE DUMBELLS
24
Q

escitalopram (Lexapro)

A 
Lex was a sad pro nazi 
SSRI
antidepressant
inhib reuptake of 5-HT
less anticholinergic and CV
sedation, bleed hyponatremia
25
Q

citalopram (Celexa)

A 
I selcect special services to hit me
SSRI
antidepressant
inhib reuptake of 5-HT
less anticholinergic and CV
sedation, bleed hyponatremia
26
Q

duloxetine (Cymbalta)

A

HTing cybals NEar my head gave me a headache
SNRI
antidepressant
inhib uptake of 5-HT and NE
dry mouth, sweating insomnia, tremor
1st line if neuropathic pain or fibromyalgia

27
Q

Vanlafaxine (Effexor)

A

Norm and Tami have fibromyalgia affecting their mouth so they can’t bang it out
SNRI
antidepressant
inhib uptake of 5-HT and NE
dry mouth, sweating insomnia, tremor
1st line if neuropathic pain or fibromyalgia

28
Q

bupropion (Wellburtin)

A 
Well Burton was sad and NEDA eat more
atypical
antidepressant
Inhib NE and DA
decreased appetite, significant insomnia, risk of seizure
29
Q

cyclobenzaprine (Flexeril)

A

My flexible friend cycled to get rid of spazzing
muscle relaxant
central acting antispasmodic
onset 1 hr peak 2-8 hrs lasts for 12-24

30
Q

alprazolam (Xanax)

A 
I only pop a xanny in my benz when im nervous in
benzo
anxiety
binds to BZD
sedation, ataxia
prn use preffered
31
Q

buspirone (buspar)

A 
I took the bus 3 weeks ago, im worried i missed my stop
anxiety
dizziness sedative
no risk of buse
3 weeks to see effect
32
Q

quetipine (seroquel)

A

SGA
schizophrenia
block D2 receptors more affinity for 5-HT2
EPS possible, METABOLIC DYSFUNCTION

33
Q

lithium

A 
Bipolar
manage acute manic episode may take 5-10 days for response
POLYURIA, POLYDIPSIA LITH TOX
L- levels
I- increased uniation
T- thirsty, tremors
H - hair thinning, hypothyroidism
I - interactions 
U - upset stomach
M - muscle weakness
S - Skin effects
34
Q

mthylphenidate (concerta, ritalin)

A

the meth concert blocked my great DANE from coming and it hurt my heart
ADHD
block DA and NE reuptake
weight loss, disphoria, CV RISK AND ABUSE POTENTIAL
monitor vital signs

35
Q

mixed amphetamine salts (adderall)

A

block DA and NE reuptake
weight loss, disphoria, CV RISK AND ABUSE POTENTIAL
monitor vital signs

36
Q

atomexotine (Strattera)

A 
I selected to go to the suicide boyz conert in the streets
ADHD
SELECTIVE NE
suicide risk 
2-4 weeks full benefit 6-12 weeks
37
Q

tzanidine

A 
Taz used to be a spaz but now he's sleepy
alpha 2 agonist
spasticity
drowsiness sedation
2-3times a day 
start at bedtime to titrate slowly
selectively bind to a2 receptors
38
Q

botulinum toxin (botox)

A

blocks ACh into NM jx

rare cases of spread to distal tissues for hours/weeks after injection

Final Pharm (4 decks)

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