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Final Pharm > Extra classes > Flashcards

Extra classes Flashcards

1
Q

Bisophosphonates

A

Osteoporosis and hyperparathyroidism

Decreases bone turnover

Atypical femur fracture
ONJ

First line for osteoporosis

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2
Q

Anti-RANKL

A

My rank dropped because of my weak bones and jaw
Osteoporosis

Decreases bone turnover

Atypical femur fracture
ONJ

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3
Q

Sclerotin Inhib

A

Osteoporosis

Decreases bone turnover

Arthralgia, Atypical femur fracture, ONJ

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4
Q

Thiazolidinediones TZDs

A

TeeZ nuts are sensitive especially in females

Diabetes Type II

increased sensitivity

low hypoglycemia, increased bone fracture, HF

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5
Q

DPP-4 inhib

A

Deplete glucose

Diabetes Type II

decreased glucagon secretion

low hypoglycemia, best tolerated

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6
Q

SGLT2 inhib

A

Secrete Glucose

Diabetes Type II

increased urinary glucose excretion

genitourinary infections, diabetic ketoacidosis

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7
Q

GLP1 receptor agonist

A

glucose lower

Diabetes Type II

increased insulin secretion, decreased glucose secretion

GI

approved for weight loss

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8
Q

Insulin

A

Diabetes Type I and II

basal always working
bolus bowl of food

increased glucose uptake

HYPOGLYCEMIA

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9
Q

MOA-B inhib

A

PD

inhibit MAO-B - increases dop

SEROTONIN SYNDROME
High first pass effect

used after levodopa carbidopa

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10
Q

COMT inhib

A

Comet assisted in parting the sky

PD

Inhibit COMT - decrease breakdown of I-dopa

involuntary movements, nausea

adjunct therapy with L-dopa

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11
Q

Amatadine

A

PD

unknown

Livedo Reticularis, dry mouth, constipation

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12
Q

Anticholinergic therapy for PD

A

PD

antagonizes muscarinic receptors to prevent acetylcholine

anticholinergic effects

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13
Q

a2 antagonist

A

antidepressant

increased 5HT and NE release

sedation, increased appetite, constipation

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14
Q

vilazodone

A

My village is sad
antidepressant

inhib NE reuptake and 5HT1a agonist

N/D HA

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15
Q

vortioxetine

A

Going down a vortex bc of my sexual dysfunction
antidepressant

unclear

nasea, sexual dysfunction

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16
Q

tricyclic antidepressant

A

antidepressant

inhib reuptake of 5HT and NE

weight gain sedation
overdose = cardiac conduction abnormalities

17
Q

MAO inhib

A

antidepressant

increase 5HT, NE, and DA by inhib MAO

OH, serotonin syndrome

18
Q

FGA

A

antipsychotic

block D2 receptors

EPS, hyperprolactinemia

second line Tx

19
Q

Antiepileptic meds

A

blocks Na, Ca entry; glutamate release; glutamate binding; block GAT1 and GABA-T prolong opening of GABA-A

acute- concentration dependent or idiosyncratic
chronic - weight gain, neurotox, hypothyroidism

many require monitoring
some NTI drugs
many DDIs

20
Q

NMDA

A

used for alzheimer’s and watch for falls

Final Pharm (4 decks)

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