Larynx/hypopharynx Flashcards
Glottis staging: Tumor limited to one vocal cord with normal mobility
T1a
Glottis staging: tumor involves both cords with normal mobility
T1b
Glottis staging: Tumor extends to supraglottis and/or subglottis, and/or with imparied vocal cord mobility
T2
Glottis staging: Tumor limited to the larynx with vocal cord fixation and/or invasion of the paraglottic space and/or inner cortex of the thyroid cartilage
T3
Glottis staging: Tumor invades through outer cortex of the thyroid cartilage and/or invades tissues beyond the larynx
T4a
Glottis staging: Tumor invades prevertebral space, encases carotid artery, or invades mediastinal structures
T4b
Glottis staging: clinical: metastasis in a single ipsilateral lymph nodes, 3 cm or smaller in greatest dimension ENE -
cN1
Glottis staging: clinical: Metastasis in a single ipsilateral lymph node, > 3cm but < 6cm, ENE-
cN2a
Glottis staging: clinical: Met in multiple ipsilateral nodes, all < 6cm and ENE-
cN2b
Glottis staging: clinical: Metastasis in a lymph node > 6 cm and ENE -
cN3a
Glottis staging: clinical: Met in bilateral or contralateral nodes, < 6 cm and ENE -
cN2c
Glottis staging: clinical: Met in node with overt ENE +
cN3b
Glottis RT Tx paradigm T1-2N0
Definitive RT 63-65.25 Gy in 2.25 Gy fx
or Surgery with post op CRT for ENE, RT for unresectable + margin/pT3/pN2 or pN3, PNI/LVSI subglottic extension, consider RT for pN1
Glottis RT Tx paradigm T3N0-3
CRT
or surgery with PORT for pN1 with risk factors, PORT/chemo for ENE or other risk features
or induction
Glottis RT Tx paradigm T4aN0-3
surgery with PORT/chemo for ENE, + margin, other risk factors
Glottis RT Tx paradigm T4bN0-3
CRT or induction CT followed but CRT/RT or RT (palliative) based on PS