Laryngology Flashcards
Approximately what percent of patients with bilateral vocal cord paralysis never require tracheostomy?
50%.
In what percent of patients with bilateral vocal cord paralysis is decannulation possible after one of these procedures?
70%.
When is medialization thyroplasty appropriate for the treatment of vocal cord paralysis?
Any stable, definitive paralysis in a patient without surgical contraindications.
What substances can be used for temporary vocal cord medialization?
Autologous fat, Gelfoam, collagen, and micronized Alloderm.
What are the advantages of performing this procedure under local?
Desired voice quality can be precisely obtained and airway can be continually evaluated.
What are the indications for endolaryngeal stenting after open repair of laryngeal injuries?
Disruption of the anterior commissure; multiple displaced cartilage fractures; and multiple, severe lacerations.
What symptom, other than hoarseness, is most likely to be improved by medialization thyroplasty and arytenoid adduction?
Dysphagia.
What are the two primary techniques of laryngeal reinnervation?
End-to-end anastomosis of the recurrent laryngeal nerve to the ansa hypoglossi or nerve-muscle pedicle flap to the thyroarytenoid muscle (using the ansa and a small piece of strap muscle).
What is the most likely cause of prolonged dysphonia and vocal fold stiffness after surgery for Reinke’s edema?
Excessive suctioning of the superficial lamina propria.
True/False: Previous Teflon injection is a contraindication to medialization thyroplasty.
False.
True/False: When injecting Teflon in the vocal fold, it should be placed as far medially as possible.
False: It should be placed as far laterally as possible.
What is the most common immediate complication after repair of laryngeal injuries?
Granulation tissue.
What is the most common complication after insertion of a Blom-Singer indwelling voice prosthesis?
Granulation tissue.
What is the primary disadvantage of the indwelling voice prosthesis compared with the nonindwelling prosthesis?
Higher rate of fungal colonization.
Which laryngoscopes are best for visualizing the anterior commissure or the subglottis?
Holinger and Benjamin.
A 69-year-old man with terminal lung cancer has severe hoarseness secondary to left vocal cord paralysis. What would be the best treatment option?
Left vocal cord medialization with Teflon paste.
What are the four main categories of procedures for unilateral vocal cord paralysis?
Medialization thyroplasty, arytenoid adduction, intracordal injection, and laryngeal reinnervation.
What would be the best treatment for a 6o-year-old woman who experiences severe dysphagia and aspiration after removal of a high right vagal schwannoma?
Right medialization thyroplasty, arytenoid adduction.
What is the optimal treatment for presbylaryngeus?
Speech therapy for 1year; if that fails, then bilateral medialization thyroplasty.
Into which plane is the implant placed during medialization thyroplasty?
Subperichondrial.
What is the aim of laryngeal reinnervation?
To prevent atrophy of the thyroarytenoid muscle.
What is the aim of arytenoid adduction?
To pull the muscular process of the arytenoid laterally, resulting in adduction and lowering of the vocal process.
What are five ways to restore the airway in patients with bilateral vocal fold paralysis?
Tracheostomy, stitch lateralization of the arytenoid(s), laser arytenoidectomy, unilateral or bilateral laser cordectomy.
True/False: Arytenoid adduction is contraindicated for the treatment of presbylaryngeus.
True: Arytenoid adduction is contraindicated in any patient with mobile vocal folds.
Surgical disruption of which layer of the vocal cord is most likely to lead to vocal fold scarring?
Vocal ligament (highest amount of collagen and fibroblasts).
Under what anatomic conditions is medialization laryngoplasty most efficacious in the treatment of vocal fold scarring?
When arytenoids are mobile, glottic gap is >1.5 mm, and soft tissue deficiency is confined to the anterior 1/3 of the vocal fold.
In what % of patients with bilateral vocal cord paralysis is decannulation possible after one of these procedures
90%
What is the incidence of mediastinitis after diverticulectomy
What is the normal size (height) of the saccule
15 mm in 8°/o.
What % of patients with long-term tracheostomies are colonized with Pseudomonas
>60%.
What % of patients with esophageal stricture will develop esophageal cancer
1 -4%.
What are the 3 stages of injury after caustic ingestion
- Necrosis, bacterial invasion, sloughing of the mucosa. 2. Granulation tissue and reepithelialization (day 5 - several weeks). 3. Scar formation and contraction.
What is the starting dose of botulinum toxin for treatment in a patient with harsh, strained voice with intermittent pitch breaks and glottal fry
1.0 - 2.5 MU into each thyroarytenoid muscle if administering bilaterally; 5 - 30 MU if administering unilaterally.
What % of cases of SO are familial
12%.
What % of laryngectomy patients who fail voice restoration following tracheoesophageal puncture (TEP) suffer from cricopharyngeal spasm
12%.
In what age groups is caustic ingestion most common
18 - 24 months, 20 - 30 years.
What is the incidence of tracheoinnominate fistula after tracheostomy
2%.
What is the tracheal wall mucosal capillary pressure
20 - 30 mm Hg.
What % of patients with glottic insufficiency will attain complete closure after voice therapy
20%.
When is the ideal time to perform endoscopy after ingestion
24 - 48 hours post-ingestion.
What does medical management of laryngeal injuries consist of?
24 hours or more of airway observation, voice rest, elevation of the head, humidified air, H2 blockers, steroids; antibiotics if lacerations are present.
What % of patients with tracheoinnominate fistulae survive
25%.
What is the lethal dose of botulinum toxin for humans
2500 to 3000 MU.
What is the starting dose of botulinum toxin for treatment in a patient with a breathy, hypophonic voice with abnormal whispered segments of speech
3.75 MU into the most active posterior cricoarytenoid muscle.
What is the mortality from colon interposition
4- I 5%.
What % of patients with unilateral vocal cord paralysis require surgical treatment
40%.
After 3 months of voice therapy, what % of benign vocal cord lesions will reduce in size or resolve
46% will reduce in size and 11 °/o will completely resolve.
Approximately what % of patients with bilateral vocal cord paralysis never require tracheostomy
50%.
What % of all instances of tracheal bleeding developing 48 hours or longer after surgery are caused by tracheoinnominate fistulae
50%.
What % of children with esophageal burns will develop esophageal stricture
7 - 15%.
What % of patients experience improvement in voice after nerve-muscle implantation
76%.
What % of patients without oropharyngeal burn will have evidence of esophageal injury
8 - 20%.
How many serotypes of botulinum toxin exist? Which is the most useful clinically
8 serotypes (A through G) with type A being the most useful.
What is the incidence of complications after PEG
9-15%).
What % of patients are eventually able to swallow well after this procedure
92%.
Voiceless consonants is suggestive of what disorder
Abductor SO.
What is a laryngocele
Abnormal dilatation of the laryngeal saccule.
What % of patients develop a granuloma after Teflon injection
About 35°/o.
How does the injury differ after ingestion of acidic substances versus ingestion of basic substances
Acidic substances cause coagulation necrosis; the eschar limits the depth of injury. Basic substances cause liquefaction necrosis and are likely to cause deeper injury.
What are the two types of spasmodic dysphonia (SO)
Adductor and abductor.
Which is more common
Adductor SO.
Which of these is characterized by a harsh, strained voice with inappropriate pitch breaks, breathiness, and glottal fry
Adductor SO.
The inability to sustain vowels during speech is suggestive of what disorder
Adductor SO.
When should PEG be performed when done as part of an oncologic resection
After the primary resection to avoid inadvertent spread of tumor cells to the gastrostomy site.
What factors are associated with the highest success with esophageal dilatation for treatment of strictures secondary to caustic ingestion
Age
Which drugs potentiate the effect of botulinum toxin
Aminoglycoside antibiotics.
When is medialization thyroplasty appropriate for the treatment of vocal cord paralysis
Any stable, definitive paralysis in a patient without surgical contraindications.
Where are vocal nodules most commonly located
At the junction of the anterior I /3 and posterior 2/3 of the vocal fold.
What substances can be used for temporary vocal cord medialization
Autologous fat, Gelfoam, collagen, micronized alloderm.
What is the test of choice for diagnosis of Zenker’s diverticulum
Barium swallow.
Where are internal laryngoceles located
Beneath the mucosa of the false vocal cord and aryepiglottic folds.
What is the best way to successfully restore the airway in a one-stage procedure in patients with bilateral vocal fold paralysis (other than tracheostomy)
Bilateral laser cordotomy.
What problems are seen in patients with vocal cord paralysis due to a brainstem disorder
Breathiness; pitch changes; chronic aspiration; VPI.
What are the typical features of abductor SO
Breathy, effortful hypnotic voice with abnormal whispered segments of speech.
When do most laryngoceles present
Can present at any time, but most commonly arise in the sixth decade of life.
What is the most significant early complication of this procedure
Cervical anastomotic leak (50%).
What is the most significant late complication of this procedure
Cervical anastomotic stricture ( 44% ).
What is the preferred method of treatment for SD
Chemical denervation with botulinum toxin.
Which patients are at a higher risk of pneumothorax after tracheostomy
Children.
What is the most common esophageal bypass procedure
Colon interposition.
What are the indications for esophageal bypass
Complete esophageal stenosis and failure to establish a lumen with dilatation. Irregularity and diverticuli of the esophagus. Mediastinitis secondary to dilatation. Fistula formation. Inability to maintain a lumen of 40 Fr or greater with dilatation. Patient intolerance of frequent procedures.
What is the best test to differentiate between cricopharyngeal spasm and stricture in patients who fail voice restoration following TEP
Contrast video fluoroscopy.
What are the signs of a tracheoesophageal fistula after tracheostomy
Copious secretions, food aspiration, and air leak around the cuff ‘with abdominal distension.
What test should be done if the history and physical exam do not explain the etiology of vocal cord paralysis
CT scan from skull base to A-P window.
Which complication is most likely to be avoided with endoscopic diverticulectomy versus open diverticulectomy
Damage to the recurrent laryngeal nerve.
How does the pattern of the EMG wave appear in the presence of a myopathy
Decreased amplitude, normal frequency.
How does the pattern of the EMG wave appear in the presence of a neuropathy
Decreased frequency with normal amplitude.
What effect does damage to the superior laryngeal nerve have on voice
Decreased range of pitch.