Larry

Question 1

what is linear growth

Answer 1

increased in the height of an organism and lenght of arms and legs

Question 2

what is body mass growth

Answer 2

increase in soft tissue resulting in increase in weight

Question 3

what is the main influence related to body mass

Answer 3

energy intake vs energy expenditure

Question 4

what kind of cells in the anterior pituitary does ghrh activate

Answer 4

somatotroph

Question 5

what is the hormone that is used for negative feedback of gh

Answer 5

insulin like growth factor

Question 6

name target tissues of insulin like growth factor

Answer 6

liver, skeletal muscle

Question 7

growth hormone release is usually released during what times

Answer 7

during feeding times , it is stiumulated by the release of ghrelin from the stromach

Question 8

is growth hormone usually increased or decreased in gastric bypass pts

Answer 8

depressed!

Question 9

what are pre puberty growth hormone levels like

Answer 9

they are very high after puberty the levels will drop

Question 10

why is there decreased growth hormone in adults

Answer 10

there is smaller PULSE WIDTH & AMPLITUDE rather than a decrease in the number of pulses

Question 11

what 3 amnio acids increase the release of growth hormone

Answer 11

phenylalanine, leucine and arginine

Question 12

what is the most important effect of growth hormone

Answer 12

stimulation of longitidinal bone growth

Question 13

what 2 things are stimulated in longitudinal bone growth

Answer 13

osteoblasts

chondrocytes

Question 14

how does growth horome increase muscle mass

Answer 14

growth hormone causes release of IGF which stimulates amino acid uptake into muscle cells which leads to protein production and muscle growth

Question 15

how can liver dysfunction affect longitudinal growth

Answer 15

IGF is produced in the liver, so if there is dysfunction of linear growth

Question 16

cretinism is caused by what

Answer 16

fetal hypothyroidism

Question 17

does fetal hypothyroidism affect birth weight

Answer 17

no it caused mental retardation

Question 18

what are the sx of acquired hypothyroidism

Answer 18

reduce bone advancement but it wont cause mental retardation

Question 19

what does hypersecretion of growth hormone cause in pre puberty children

Answer 19

gigantism

Question 20

Is IGF higher before or after puberty

Answer 20

before. as growth hormone levels reduce, so do IGF levels

Question 21

describe the effect of increased growth hormone in adults and pre puberty kids

Answer 21

gigantism = kids 
acromegaly  = adults

Question 22

describe the glucose and insulin status of people with acromegaly

Answer 22

insulin resistance

glucose intolerance

Question 23

do pts with growth hormone have increased or decreased liploysis

Answer 23

increased

Question 24

does protein synthesis increase or decrease with acromegaly

Answer 24

increase

Question 25

what can cause dwarfism

Answer 25

hyposecretion of growth hormone

Question 26

whats the problem with african pigmes

Answer 26

failure to generate IGF-1 in the liver

Question 27

what causes laron dwarism

Answer 27

growth hormone receptor deficincy

Question 28

what are the causes of too much and too little thyroid hormone in kids

Answer 28

too much = NO EXCESSIVE GROWTH

too little = stunted growth

Question 29

what is cortisols effect on growth hormone releasing hormone

Answer 29

it inhibits the release of growth hormone releasing hormone

Question 30

do estrogen and testosterone have a role pre puberty

Answer 30

no