Large for dates Flashcards

1
Q

Which standard measurement = large for date?

A

symphyseal-fundal height >2cm for gestational age.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Diagnosis of foetal macrosomia (centiles).

A

USS EFW >90th centile, AC >97th centile

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the NICE recommendation re large for dates babies and management?

A

NICE: in the absence of any other indications, induction of labour should not be carried out simply because a healthcare professional suspects a baby is large for gestational age.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is polyhydramnios?

A

excess amniotic fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are some foetal causes of polyhydramnios?

A

anomaly
monochorionic twins
hydros fetalis (Rh immunisation)
viral infection (erythrovirus B19, toxoplasmosis, CMV)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the main maternal cause fo polyhydramnios?

A

diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Symptoms for polyhydramnios.

A

abdominal discomfort
pre-labour rupture of membranes (PROM)
preterm labour
cord prolapse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Pregnant lady with abdominal discomfort, tense shiny abdomen presents in suspected preterm labour. You are unable to feel foetal parts - diagnosis?

A

polyhydramnios

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Polyhydramnios investigations?

A

OGTT
serology - toxoplasmosis, CMV, parvovirus.
antibody screen
USS - foetal survey; lips, stomach

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

diagnosis of polyhydramnios.

A

USS confirmation:
amniotic fluid index >25cm
deepest venous pool >8cm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

If a diabetic mother with polyhydramnios is at 40+3 weeks - what do you do?

A

induction of labour at 40 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

WHO definition of GDM.

A

carbohydrate intolerance resulting in hyperglycaemia of variable severity with onset or first recognition during pregnancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

congenital anomalies are related to what if mother has diabetes?

A

HbA1c at booking

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What recommendations are made pre-pregnancy to a woman with diabetes?

A
HbA1c: 48mmol/mol (6.5%)
avoid pregnancy if 86mmol/mol (10%)
stop ACE-i, statins
high dose folic acid 5mg (3m before conception-12w pregnancy)
LDA from 12w
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

When do diabetic mothers get an additional foetal anomaly scam and when do they deliver by?

A

scan at 18-20 weeks

deliver at 38w (earlier if complications)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

When and what is the diagnostic test for GDM?

A

OGTT at 24-28 weeks.

venous FBS - given 75g glucose solution - measure 2hr venous glucose - minimal activity between tests

17
Q

What are SIGN diagnostic values for GDM from diagnostic test?

A

fasting >/= 5.1 mmol/l

2-hour >/= 8.5 mmol/l

18
Q

Describe glycemic targets during pregnancy.

A

minimum 4x /day (pre-meals and before bed)
fasting: 3.5-5.5 mmol/l
1-hr: <7.8 mmol/l

19
Q

Describe delivery timings for GDM when on:

i) insulin
ii) metformin
iii) diet alone

A

insulin: 38-39 weeks
metformin: 39-40 weeks
diet alone: 40-41 weeks

20
Q

What are the main risk factors for future development of T2DM in the post-natal period?

A
obesity
insulin use during pregnancy
fasting glucose levels from OGTT in pregnancy
IGT post-partum
ethnic group
21
Q

When determining chorionicity on USS, what is being looked for?

A

shape of membrane and its thickness

foetal sex

22
Q

Which twin type are at higher risk fo pregnancy complications?

A

monochorionic/monozygous twins

23
Q

If you saw lambda sign on USS of pregnant lady - what would you tell her?

A

dichorionic diamniotic twins

24
Q

If you saw T-sign on USS of pregnant lady - what would you tell her?

A

monochorionic diamniotic twins

25
What are some signs of multiple pregnancies?
high AFP large for dates uterus multiple foetal poles
26
Pregnant lady presents at 15 weeks with excessive sickness and you measure high AFP - diagnosis?
twins/multiple pregnancy
27
How often do pregnant ladies with MC twins have clinic appointments?
every 2 weeks from 16/40
28
How often do pregnant ladies with DC twins have clinic appointments?
every 4 weeks
29
When do you deliver MCDA/DCDA babies?
DCDA twins at 37-38 weeks | MCDA twins after 36+0 (w/ steroids)
30
When would you aim to deliver twins vaginally?
if twin one is cephalic
31
What is the inter-twin delivery time goal?
<30 mins
32
What is a monozygotic pregnancy?
splitting of a single fertilised egg
33
What is a dizygotic pregnancy?
fertilisation of 2 ova by 2 spermatozoa
34
With regards to monozygotic twins, their chorionicity depends on when the fertilised ovum splits. Describe the timeline of twin types & development.
Day 0-3 after fertilisation: DCDA Day 4-7 after fertilisation: MCDA Day 8-14 after fertilisation: MCMA Day 15 onwards: conjoined twins
35
In selective growth restriction, how do you calculate EFW discordance?
(larger EFW-smaller EFW) / larger EFW x100
36
What is TTTS?
twin-to-twin transfusion syndrome | syndrome with artery-vein anastomoses; donor twin perfuses the recipient twin; rare after 26/40
37
How do you diagnose TTTS?
oligohydramnios-polyhydramnios (oly-poly)
38
What is the treatment for TTTS?
<26/40: fetoscopic laser ablation >26/40: amnioreduction/ septostomy 34-36/40: deliver