Large Animal Medicine II Final Exam Flashcards
Swine karyotype is
2n= 38
Now, daily growth of grower finisher pigs went up to
950-1200 g/day
In swine medicine, method to optimize health, welfare, and production in a population of animals through the systematic analysis of relevant data and through regular objective observations such that informed timely decisions are made to improve herd management over time.
Herd Health Management approach (HHM)
Herd health management is based mainly on
Prevention. Based on identification of risk factors for disease
Sows produce colostrum containing that has this to enhance uptake of intact immunoglobulins
anti-trypsin factor
T/F stomach pH in piglets is close to neutral making young piglets susceptible for enteral infections
True
In piglets 2-10 days old, diarrhea, low mortality. Multifocal suppurative and erosive colitis. Confirmed by ELISA of fresh feces. Tx with virginiamycin and tylosin in piglets
Clostridium difficile associated enterotoxemia
Causes enterotoxemia in piglets 2-10 days old. Minimal gross lesions but multifocal suppurative enteritis with large Gram + rods. Isolation and genotyping of a beta 2 toxin is warranted. Tx with bacitracin in sows and salinomycin in piglets. Vaccination is available
Clostridium perfringins type A associated enterotoxemia
Piglets 1 day to 2-4 weeks old postweaning. Virulence includes fimbria, enterotoxins, endotoxins, and capsules. Dams are carriers. Poor sanitiation and chilling play role. Severity is related to dose ingested and immunity from colostrum. Can survive in contaminated buildings and keep infecting. Shivering, watery diarrhea, and vomiting occur. Dx with culture and PCR. Tx with antimicrobials. Practice good sanitation and vaccination twice before farrowing
E. coli (Enteric colibacilloisis)
Acute and fatal entertoxemia of recently weaned pigs. Characterized by edema, sudden death, and neuro signs such as paddlinging and squealing.
Edema disease (colibacilosis)
Several serotypes of E. coli
Usually in confinement raised 1-3 weeks old nursing piglets. When unexposed pigs are placed in contaminated area. Carrier sows are the source. Signs are yellow pasty diarrhea, dehydration, rough hair coat. No response to antimicrobials. Tx with Toltrazuril
Coccidiosis (Isospora suis)
Usually in piglets 1-6 weeks old. Diarrhea, vomiting, non fatal. Enteritis with moderate villous atrophy. Dx with ELISA or FAT of feces.
Rotaviral enteritis
All age groups susceptible but mostly piglets <4 weeks old. Acute form with high mortalitiy and endemic form is less serious. Dx with FAT or IHC on intestine of acutuely affected pigs or PCR of feces.
Transmissible gastroenteritis
Most important strep infection in pigs. Usually nursing or recently weaned piglets. Septicemia, meningitis, polyarthritis, bronchopneumonia. Zoonotic. Isolated from nasal cavity and tonsils of pigs. Eliminate stress and overcrowding. Vaccinate sows. Tx with antibiotics
Streptococcus suis
Syndrome usually within 3 days of farrowing and causes inadequate milk production. Hypogalactia, weakness, anorexia, sternal recumbancy, resistent to allow nursing. Cause unknown. Resolved by proper sanitiation, exercise, and nutrition
Hypogalactia or Mastitis, Metritis, Agalactia (MMA)
In pigs mastitis is most commonly
Enviornmental
Dermatitis usually seen in 4-12 week old piglets. Reddened raised ring shaped lesions usually on ventral abdomen. Dx with exam and no treatment required. Non pruritic and no affect on pigs. Cause unknown
Pityriasis rosea
Abnormalitiy of neonatal pigs with lateral extension of the hind legs with inability to adduct legs. Myovibrillar hypoplasia related to delayed development. Genetic disposition, slippery floors, and PSS are causes. Tx by tying legs together
Splay leg
Inheritied condition. Abscence of discrete areas of skin. Hydroureter and hydronephrosis also seen with condition. Fetuses may be aborted or born.
Epitheliogenesis imperfecta
Treatment for Erysipelas
Penicillin or antiserum
Caused by staphylococcus hyicus. Pigs less than 8 weeks old. Brownish spots with serum or exudate. No pruritis. Isolate affected pigs, and spray pigs with 10% bleach, chlorohexadine, Durvet or dilute iodine
Greasy pig disease (Exudative Epidermitis)
Caused by Brachyspira hyodysenteriae. Mucohemorrhagic diarrhea with marked inflammation limited to the large intestine. Persists in rodents and water. Eradication program in place and replace herds.
Swine dysentery and spirochaetal colitis
Results in septicemia, enterocolitis, and asymotimatic swine. Disease is less common but occurs mostly in weaned pigs. Often appears during stressful events. Tx with carbodox, gentamycin, neomycin, and others
Salmonellosis
Causes septicaemic salmonellosis in swine. Acute onset of outbreak with acute death loss in a group of apparently thrifty pigs
Salmonella chorerasuis
Causes enterocolitic salmonellosis in pigs.
Salmonella typhimurium
Obligate intracellular organisim. Causes hyperplasia of crypt enterocytes with inflammation and ulceration in young adults and grower pigs. Outbreaks can be associated with stress. Usually results in subclinical disease. Acute phse can have brown to black diarrhea, and rapid death. Elimination is difficult, vaccinate pigs. Tx with tylosin, tetracycline, linocmycin and others
Porcine Proliferative Enteritits
Lawsonia intracellularis
Usually in 6-20 weeks old pigs in USA. Secretes 4 enterotoxins. Trasmission from direct contact, overstocking, stress. Pigs remain carriers. Sudden deaths common. Diarrhea, high temps, cyanosis, chronic cough, stiffness. Control with closed herd and replacement with free farm pigs. Tx is Parenteral with tiamulin, tulathromycin and others
Actinobacillas Pleuropneumonia
Caused by toxigenic strains of Bordetella bronchisepticica and Pasteurella multicodia (type D). Snuffling, sneezing, snorting, and nosebleeds. Atrophy of turbinates in nose. Transmitted in dust and with poor ventilation. Pigs may have dirty face from obstructed tear ducts. Improve husbandry to treat and vaccinate.
Atropic Rhinitis
Post weaning multisystemic wasting syndrome. Usually nursing and growing pigs. Lyphocytic depletion in lymph nodes with histiocytic infiltration. In utero infection possible. Can cause repro failure and abortion. Almost all herds in USA are seropositive. Gradual wasting, unthriftiness, rough coat, pallor, diarrhea, icterus, death. Control with quarantine and disinfection. Euthanize affected pigs. No treatments
Porcine cirovirus type 2
Viral disease in pigs characterized by repro failure and respiratory disease in pigs of any age. Most economically significant disease in swine in the USA. Persists in long term carrier pigs which become immune and keep shedding. Virus is highly infectious.
Porcine reproductive and respiratory syndrome (PRRS)
Coronavirus. Acute outbreaks of severe diarrhea, vomiting, and high morbidity. Short icubation period. Not a foreign animal disease in the USA. Dx with ELISA, PCR, and EM. Control with biosecurity and vaccines. Tx with supportive therapy and clean enviornment.
Porcine Epidemic Diarrhea
Occurs as result of deficiency in pregnant sow, or genetic defect in synthesis. Leads to weak or dead piglets, mucinous edema, thick skin, enlarged goiter.
Iodine Deficiency
Colostrum and milk from sow only provide ____ daily iron requirement to piglet
15-20%
T/F Iron dextran can be administered to piglets in neck muscles parenterally after 7 days of age
False
THE MEAT!!!
Observed in 2-4 month old pigs. Usually in pigs not allowed access to soil or not supplemented. Most often caused by consumption of excessive calcium. Skin lesions and reduced growth rate are signs.
Zinc responsive dermatosis (Parakeratosis)
Disease of growing bones. Usually caused by dietary deficiency of vit D or phosphorus. Control with balanced diet
Rickets
Lesion of mature bones. Occurs in profilic sows that mobilize minerals for high milk production. Often results in fractures in latter part of nursing. Control with balanced diet and exercise
Osteoporosis
Causes mulberry heart disease (sudden death), Hepatosis dietetica, and white muscle disease
Vit E and Selenium deficiency
Caused by fungus growing on peanuts, corn, wheat, and other grains. Young nursing pigs or weaned growers at risk mostly. Toxins reduce growth rate and are immunosuppresive. Causes hepatotoxicosis, fibrotic liver, and ascitis.
Alfotoxicosis
Fungus in many grasses and cereal grains. Alkaloids are cause of disorder. Toxins result in ischemic necrosis, dry gangrenous sloughing, and reduced litter and mammary size.
Ergotism
Claviceps purpurea
Toxic compound produced by fungus. Cytotoxic to many cell types and strongly immunosuppressive. In moldy caked feed. Causes crusting and ulceration of the skin on the snout, lips, and prepuce.
Fumonisin
Fusarium species
In moldy corn and other cereals. Has estrogenic effect resulting in vulvovaginitis and precocius mammary development. Passed to offspring in milk. Can effect boars also
Zearalenone (F-2)
Fumonisin toxicosis
Acute and characterized by meningeoencephalitis, polyserositis, polyarthritis and bacterial pneumonia. Sporadic occurance usually 3 week -4 month old piglets. Stressful events and enviornment predispose. Can be isolated from nasal cavity of normal pigs. CNS signs, sudden death, joint issues. Tx antibiotics and sulfonamides.
Haemophilus parasuis (Glasser’s disease)
Widespread chronic respiratory disease with coughing and reduced feed efficiency. Pigs at weaning are more commonly affected. Can be part of a respiratory complex. Carrier swine are common. Tx with lincomycin and others.
Mycoplasmal pneumonia (Enzootic pneumonia)
Cause of mycoplasmal pneumonia in pigs
mycoplasma hyopneumoniae
Viral disease in swine, sudden onset of fever, discharge, weakness, and paroxysmal coughing. Course is 5-7 days. H1N1 is common serotype. Vaccinate, maintain closed herd, and use antimirobials for secondary infections
Swine influenza
Growth cartilage disease in rapidly growing pigs. Cause unknown. Abnormal gait and lameness with pathologic bone/cartilage lesions. Common sites are femoral condyle, humeral condyle/head, scapula, lumbar vertebrae. Genetics plays a role. Results in sows being culled
Osteochondrosis
Occurs in pigs either from water deprivation or ingestion of too much salt. Signs worsened by sudden access to water. Blindness, deafness, head pressing, dog sitting, and paddling. Results in meningeal and cerebral perivascular cuffing by eosinophils in the brain. Pigs usually die reguardless of treatment.
Salt poisoning
Referrs to destruction of part or all of the pars esophagea with bleeding. Pigs 8 weeks and older (mostly in pigs 120lbs to market weight). Unknown risk factors. Usually dead with pallor and melena. Tx with Vit K and hematinics.
Gastric ulcers
Whipworm. Feeder/finishers and mature swine. Mucois or mucohemorrhagic diarrhea with loss of condition. Located in large intestine. No eggs until 8 weeks post infection. Can diagnose early with histopathology or mucosal scrapings
Trichuris suis
Maintenance animal or FMD. Carried in pharyngeal tissue 4-6 months
Sheep and Goat
Animal amplifier for FMD. No carrier status
Pigs
Species indicator for FMD. Carried in pharyngeal tissue 6-24 months
Cattle
Highly infectious often fatal swine disease caused by flavivirus. Loss of appetite, weakness, fever, leukopenia. Spread between animals.
Classical swine fever
Acute highly contagious fatal disease in swine caused by double stranded DNA Asfivirus. Warthog reservoirs. No vaccine. Incubation 5-19 days. High fever, erythema, cyanosis, bloody diarrhea, abortion, death.
African Swine Fever
Vesicular stomatitis is caused by a
Rhabdovirius
Vesicular exanthema is caused by a
Calicivirus
Swine vesicular disease is caused by a
Picornavirirus and enterovirus
When immobilizing a deer with-hold food and water for
24 hour for food
12 hour for water
Combination of drugs for immobilizing deer
Telazol and Xylazine
Federal interstate regulations for moving deer
Must have negative TB test, no signs of CWD, USDA eartage, and Current CVI health paper
To certify deer herd Brucellosis free must
Test whole herd twice every 9-15 months, then every 3 years to maintain free. All animals entering must be negative 30 days before entering herd.
In deer caused by Orbivirus. Transmitted by Culicoides (midges). Peracute disease results in dead animals. Acute has swollen tongue, foaming from mouth, ataxia. Chronic form included laminitis and weight loss. Treat with steroids, antibiotics, and supportive care but prognosis is usually poor to grave
Epizootic Hemorrhagic Disease
Causes abortions in free ranging deer. Difficult to diagnose without signs. Tx with tetracycline, blood transfusion, and fluids
Leptospirosis (L. pomona)
Cause of lymphadenopathy, respiratory disease, and emaciation in deer. Dx with cervical or comparative test. No treatment to be attempted. Public health concern.
Tuburculosis (mycobacterium bovis)
Infection in young deer (12-18 months). Signs include chronic weight loss and unthrifty appearnece, diarrhea, and hyproteinemia. Dx with fecal culture (gold standard) and ELISA. No treatment
Johnes Disease (Mycobacterium avium subspecies paratuberculosis)
Gram negative anaerobic bacteria. In soil worldwide. One of the major causes of disease/death in deer. Stress and overcrowding are predisposing factors. Common forms are as lumpy jaw and pneumonia.
Necrobacillosis
Fusobacterium necrophorum
In deer necrosis of the pharynx and larynx in young animals.
Diptheria
Most common respiratory isolates in deer pneumonia. Early detection is key to treatment. Necropsy should be priority
Trueperella, Fusobacterium, Pasteurella, Biberstenia, Mycoplasma
Most common clostridial disease in deer. Causes myconecrosis, enteritis, hemorrhagic bowel. Originated from contaminated colostrum and environment. Concern following reproductive procedures.
Clostridum perfringens type A
In poultry blood is usually used for
Serology
In poultry swabs are usually used for
Bacterial isolation
Normal chicken heart rate
220-360 bpm
Normal chicken respiratory rate
12-37 rpm
Small pale and shrunken comb in chickens
Out of lay
Most common protozoan parasite in chickens. Causes bloody diarrhea, predisoposes to clostridium enteritis, and economic losses. Amprolium for prevention and control
Coccidosis
Eimeria tenella, acervulina, macima