Large Animal Medicine II Exam II Flashcards
“…For the prevention of infection with…”
Prevents all colonization and replication
Ex: spirovac for lepto
“… for the prevention of disease due to…”
Efficacy >80%
Bovishield for PI prevention
“….As an aid in the prevention of disease due to…”
Produces clinically significant effect in preventing disease in challenged animals. Most common claim
“…..as an aid in the control of disease due to….”
Alleviates disease severity and duration
ex: Salmonella SRP vaccine
Vaccine with less adverse reactions but possibility for shedding of virus. More closely mimics natural infection
Modified Live vaccine
Primary goal of vaccines in breeding herds
Maintain solid herd immunity to prevent pathogens.
Secondary: Boost innate immunity for calves
Goals of vaccines in replacement heifers
Two fold goal: Protect against prevalent threats. Provide basis for solid herd immunity.
Vaccine goals for market calves
Immune protection to prevalent disease challenge.
FDA licensed vaccines for almost ____ bovine pathogens
50
Minimal vaccine profile
Respiratory
7 way clostridial
Consider Lepto
+/- Brucella
You must give 2 doses of killed vaccines ____ weeks apart
2-4
_____ of individuals will not respond to vaccination.
10-15%
Calf immune systems are not mature until
4-5 months
T/F If you vaccinate a calf less than 5 months old protection will carry into adulthood
False
Animals mount a better immune response to killed vaccines or MLV?
MLV
T/F MLVs will give longer, stronger, and usually cheaper protection compared to killed vaccines
True
T/F Milk production will be effected by vaccination
True
Dont give more than 2 of these vaccines at once
Gram negative (endotoxin)
The effect of lameness on a dairy cattle herd is seen first in
Decreased milk production
The most common site for a lesion on the foot of a dairy cow is in zone
3
The average toe length for an adult dairy cow is
7.5 cm
Infectious pododermatitis occurs because of
Compromised epithelium
16 month old show steer presents with a grade 4/5 lameness due to foot rot. He is champion quality and the terminal show is in 12 days. Which of the following treatment in appropriate mg/kg dose and route is best?
- Ceftiofur crystalline free acid
- Florfenicol
- Oxytetracycline
- Tilmicosin
Ceftiofur crystalline free acid
Foot rot in sheep is
Contagious and effects the sole
Dealing with digital dermatitis and heel erosions requires
Management to enhance the enviornment
When would most cases of foot rot be observed?
- Wet concrete dairy cow 140 days PP
- Dry feedlot with 9 weight steers
- Pastured beef cows 3 weeks post rain
- Far off dry cows on DCAD ration
Pastured beef cows three weeks post rain
THe conformational issue associated with sequalae to solar ulcers is
- Proximity of coffin joint
- Attachment of extensor tendon
- Collateral ligaments of P3
- Complete lack of solar tubules
Proximity to coffin joint
Most economical and comfortable bedding in dairy cattle free stalls is
Clean sand
What is most efficacious in controlling diary cattle lameness
Free stall management
Want laying for minimum of 10-12 hours a day
Laminitis is most common in
Hind limbs.
High concentration diets.
Decreased blood flow disrupts horn production and p3 sinks from edema.
Value of radiograph images in bovine foot disease is to ascertain
Accurate prognosis for case
Infected mastitis cow gland will have _____ Somatic cell count. Mostly this type of cell ____
200,000-1,000,000 cells/mL
PMNs
Trace mastitis on CMT has _____ SCC
300,000
Weak mastitis on CMT has ______ SCC.
900,000 SCC
Strong CMT result has _____ SCC`
8.1 million SCC
Which two CMT results are subclinical
Trace (300,000) and weak (900,000) SCC
Legal SCC limit for Grade A milk
750,000 SCC
CMT is performed with ____ milk and ____ solution in each dish
2cc and equal solution
Rotate and read in 20 seconds
Major pathogens for contagious mastitis
Strep agalacea, Staph aureus, Mycoplasma bovis
Most cases of contagious mastitis are
Subclinical and persistent
Wall of cow hoof grows
5 mm/month
Sole of cow hoof grows
3mm/month
____ of lameness is found in the feet of cows
90%
____ of lameness results in loss of revenue in cattle farms
70%
85% of lameness is found in the ___ claw of ___ foot in cattle
Lateral claw of hind foot
Interdigital foot rot occurs most often in ____ due to interdigital dermis damage and opportunistic invasion
Beef cattle
Most common bacteria involved in cattle foot rot
Fusobacterium necrophorum
Contagious and epidemic in cattle, painful and environmentally transmitted. Confinement is predisposing factor
Digital dermatitis (Hairy heel wart)
Treatment for digital dermatitis in cattle
Oxytetracycline topical spray. ENVIRONMENTAL MANAGEMENT
Cause of digital dermatitis in cattle
Treponema spp. (Spirochete)
Where does issues with claw horn disruption in cattle begin in the foot?
Inside hoof at corium
Sole ulcers (Rusterholz ulcer) in cattle most often occurs in these claws
Lateral claw on hindlimb, medial claw on front feet
Treatment of spastic paresis in cattle
Tibial neurectomy and cutting part of gastroc
Most common stifle issue in cattle
Cranial cruciate tear
Casts in <150 kg cow should have ___ layers
6-8 layers
Casts in >150kg cow should have ____ layers
10-12 layers
Normal USG in cow
1.020-1.040
Cattle urinate ____ per day
10-40mL
BUN and CREA values in cattle
BUN 10-30
CREA <2
T/F Cows with anaplasmosis have hematuria (red urine)
FALSE
T/F most cystic calculi form in acidic urine
FALSE
Alkaline!
Single most important factor in urolithiasis
Water intake
Most common sites for urolithiasis
Distal sigmoid flexure and urethral process
Cause of contagious bovine pyelonephritis
Corynebacterium renale
Cause of necrotic posthitis in bulls and steers
Fusobacterium necrophorum
Cause of bovine enzootic hematuria
Broken fern
Sequalae of chronic suppurative process in kidney. No treatment
Amyloidosis
Presents as dystocia. Blue tongue and Akbane can cause. Usually cow is asymptomatic.
Hydrocephalus
Interferes with absorption of CSF at arachnoid villi and CSF pressure results in blindness and seizures. Common in animals on corn stubble in Midwest
Vitamin A deficiency
Autosomal recessive in Herefords and shorthorns. Can be from BVD 100-120 days in gestation. Calves are blind with no cerebellum
Cerebellar abiotrophy
Cause of spasmodic paralysis. Moves retrograde up axon and prevents release of GABA. Can only treat before neuronal uptake.
Clostridium tentani
Found in decaying vegetation. Exotoxins block Ach release and cause flaccid paralysis. No antitoxin or vaccine
Clostridium botulinum
Migrates up trigeminal nerve and causes neuro condition. Will see circling and dysphagia. Mononuclear inflammation. Tx with Oxytetracycline
Listeria monocytogenes
Caused by histophilus somni. Death within 36 hours. Pneumonia, neuro, and other signs. Death due to subsequent endothelial cell apoptosis. Neutrophil response seen
Thromboembolic Meningoencephalitis (TEME)
Cause of brain and pituitary abscesses in cattle. Can be a dehorning complication
Trueperella pyogenes.
Main isolate in otitis media/interna in cattle
Mycoplasma bovis
Cause of sway back (enzootic ataxia). Mostly in sheep.
Copper deficiency