Lacrimal/Nasolacrimal system Flashcards
3 Tear film layers and where they each come from
- Oily layer Meibomian Gland
- Watery portion - lacrimal gland and gland of 3rd eyelid
- Mucus - bulbar, paperbral and 3rd eyelid conjunctiva
4 functions of precorneal tear film
- antimicrobial activity
- optical clarity
- oxygen transport
- waste removal
Nerves involved in tearing
afferent ophthalmic branch of CN5, efferent psns fibers of CN7
Nasolacrimal ducts and punctae dog
upper and lower palpebral punctae, passes through lacrimal and maxillary bones, exits in the nasal vestibule, lateral to the floor of the vestibule
Nasolacrimal ducts and punctae cat
same as dog
Nasolacrimal ducts and punctae horses
palpebral punctum similar to dogs, can visualize the nasal punctum in the floor of the nasal vestibule, medially
Nasolacrimal ducts and punctae cattle and llama
similar to the horse with the exception that the nasal punctae are more dorsally and laterally located than in the horse
Keratoconjunctivitis sicca, what is it?
Decreased tear film, Dry Eyes.
the MOST important nasolacrimal system disorder. It is sight threatening and PAINFUL.
DOGs>cats>others
Clinical signs of KCS in Dog
- Decreased aqueous tear film as measured with a Schirmer tear test (STT) strip
- PAIN
- Thick mucous thread, dried ocular discharge around lids due to lack of aqueous tear
- Corneal and conjunctival changes (dry, reddened, ulcers, neovascularization, pigmentation
Clinical signs of KCS in Cat
Schirmer tear test does not work well in cats
cats show little signs like mucus, mild keratitis, repeated bouts of conjunctivitis
Breed Predispositions
Brachycephalics: Pugs, Lhasa Apsos, Shih Tzus, Boston Terriers, and English Bulldogs
small terriers such as Cairns and West Highland White
Shelties, Poodles, Golden Retrievers, Spaniels (American, English, Cavalier
Any breed predisposed to atopic dermatitis (above)
Cause of KCS in Dog
#1 Immune-mediated/Idiopathic Congenital Active infections, Previous infections CN7 damage (Cocker Spaniels) Sulfonamides and etodoloc and Loco weed poisoning in cattle out west Atropine General anesthesia (why we put lube) Iatrogenic (3rd eyelid removal or post-radiation)
Medical therapy of KCS
Medical therapy can induce natural tear production
- Cyclosporine-A – works well in predisposed dogs, not in other species (cats). Does not work in drug induced KCS. Tacrolimus also works (other calcineurin inhibitor/T-cell suppressor)
- Supportive care - artificial tears
- Abx if indicated
- Mucolytic agents - acetylcysteine
- lacrimomimetics - Pilocarpine
- Corticosteroids - dec. surface inflam. but more prone to infections
- Good hygiene
- Oral interferon
Surgical Therapy of KCS
- Temporary - tarsorrhaphy or 3rd eyelid flap
- Permanent - tarsorrhaphy, medial or lateral
- Parotid duct transposition for “Last Ditch Effort” when months of medical therapy don’t work but lots of potential complications
What is Epiphora?
Epiphora is abnormal flow of tears onto the face. Compared to decreased tear production, this is not near as big a problem to the animal.