Labs and Reference Ranges Flashcards
chem 7 panel
na cl bun glucose
k hco3 scr
wbc (hgb/hct) plt
leukocytosis
inc wbc
polycythemia
inc rbc
thrombocytosis
inc platelets
leukopenia
dec wbc
anemia
dec rbc or hgb
thrombocytopenia
dec platelets
agranulocytosis
dec in neutrophils, basophils, eosinophils
causes of agranulocytosis
propylthiouricil,methimazole, procainamid, clozapine, carbamazepine, bactrim, isoniazid
calcium total
8.5-10.5mg/dL
when to calculate corrected calcium
if the albumin is low
causes of calcium increase
vitamin D, thiazide diuretics
causes of calcium decrease
long term heparin, loop diuretics, bisphosphonates,cinacalcet
magnesium
1.3-2.1
causes of magnesium derease
PPIs, diuretics
phosphate
2.3-4.7
causes of phosphate increase
renal failure
potassium
3.5-5
causes of potassium increase
ace/arb, aldosterone receptor antagonists, aliskiren, cyclosporine, tacrolimus, potassium supplements, drospirenone, canaglifozin
causes of potassium decrease
beta 2 agonists, diuretics, insulin
sodium
135-145
causes of sodium decrease
carbamazepine, oxcarbazepine, ssris, diuretics
bicarb
venous: 24-30
arterial 22-26
causes of bicarb decrease
topiramate
BUN
7-20
causes of bun increase
renal impairment and dehydration
scr
0.6-1.3
causes of scr increase
aminoglycosiders, ampho b, cisplatin, colistimethate,cyclosporine, loop diuretics, polymyxin, nsaids, contrast dye, tac, and vanc
anion gap
5-12
wbc
4-11000
causes of wbc increase
systemic steroids
causes of wbc decrease
clozapine, carbamzepine
neutrophils
45-73%
bands
3-5%
eospinophils
0-5%
causes of eosinophil increase
parasitic infection
basophils
0-1%
causes of basophil increase
hypersensitivity reaction
lymphocytes
20-40%
causes of lymphocyte increase
viral infections, lymphoma
causes of lymphocyte decrease
bone marrow suppression, HIV or systemic steroids
RBC
- 5-5.5 (m)
4. 1-4.9 (f)
causes of RBC decrease
chemo, deficiency anemias, hemolytic anemia, sickle cell
hgb
13.5-18 (m)
12-16(F)
causes of hgb increase
esa
causes of hgb decrease
anemias
mcv
80-100
causes of mcv increase
b12 or folate deficiency
causes of mcv decrease
iron deficiency
folic acid
5-25
causes of folic acid decrease
phenytoin/fosphenytoin, phenobarbital, primidone, mtx, bactrim
vitamin b12
> 200
causes of vitamin b12 decrease
PPIs, metforomin
coombs test, direct
used to determine cause of hemolytic anemia
cause of positive coombs test
penicillins/cephalosporoins, isoniazid, levodopa, methyldopa, nitrofurantoin, quinidine, quinine, rifampin, sulfonamide
g6pd
5-14
causes of g6pd deficiency
fava beans, chloroquine, dapsone, methylene blue, nitrofurantoin, primaquine, probenecid, quinidine, quinine, rasburicase, and sulfonamides
anti-Xa
obtained 4 hours after sc
causes of increase anti-xa
heparin, lmwhs
pt
10-13
inr
<1.2 (if not on warfarin)
causes of increase in pt/inr
liver disease, daptomycin
aPTT
22-38 seconds
plts
150-450,000
causes of PLT decrease
heparin, lmwh, fondaparinux, valproic acid
albumin
3.5-5
drugs that require correction for low albumin
phenytoin, valproic acid, calcium
AST
10-40
ALT
10-40
T bili
0.1-1.2
amylase
60-180
lipase
5-160
causes of increased pancreatitis
didanosine, GLP-1 agonists, valproic acid, hypertriglyceridemia
creatinine kinase
55-170 (m)
30-135 (f)
causes of creatinine kinase increase
daptomycin, statins, tenofovir, raltegravir, dolutegravir
ldl
<100
hdl
> 60
non hdl
<130
CRP
0-0.5
fasting glucose
100-125 (prediabetes)
c peptide
0.78-1.89
UAE
<30mg/24 hrs
TSH
0.3-3
causes of tsh increase
interferons, tyrosine kinase inhibitors, lithium, carbamazepine
uric acid
3.5-7.2 (m)
2-6.5 (f)
increase in uric acid
diuretics, niacin, aspirin,pyrazinamide, cyclosporine,tac,pancreatic enzyme product, chemotherapy
causes DILE
anti-tnf, hydralazine, isoniaxid, methimazole, methyldopa, minocycline, procainamide, propylthiouracil, quinidine, terbinafine
HIV CD4 count
800-1100
pH
7.35-7.45
psa
<4
lactic acid
0.5-2.2
causes of increased lactic acid
NRTIs, metformin
causes of increase in prolactin
haloperidole, risperidone, paliperidone
RPR
used for syphilis
vit D
> 30