Diabetes (II) Flashcards

1
Q

Do not use if CrCl <30

A

metformin
SGLT-2
exenatide
glyburide

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2
Q

do not use if HF

A

TZD
alogliptin
saxagliptin

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3
Q

Do not use if peripheral neuropathy, PAD, ulcer

A

canagliflozin

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4
Q

Do not use if GI disorders

A

GLP-1

pranlintide

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5
Q

sulfa allergy, GPPD deficiency

A

SU

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6
Q

risk of lactic acidosis

A

metformin

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7
Q

risk of hepatotoxicity

A

tzd, alogliptin

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8
Q

risk of hypotension/dehydration/UTI/gentital infections

A

SGLT-2

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9
Q

risk of hyperkalemia

A

canagliflozin

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10
Q

risk of hypokalemia

A

insulin

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11
Q

risk of pancreatitis

A

DDP-4

GLP-1

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12
Q

risk of hypersensitivity reaction

A

SU
DPP-4
insulin

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13
Q

risk of ketoacidosis

A

SGLT-2

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14
Q

risk of bladder cancer

A

pioglitazone

dapagliflozin

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15
Q

risk of thyroid cancer

A

GLP-1

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16
Q

results in biggest decrease in A1c

A

insulin
metformin, SU
TZD

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17
Q

results in the greatest weight loss

A

SGLT2
GLP-1
pramlintide

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18
Q

results in hypoglycemia

A

insulin
SU
meglitinides
pramlintide

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19
Q

results in weight gain

A

insulin
SU
TZD
meglitinides

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20
Q

CVD benefit in patients with T2DM

A

empagliflozin
liraglutide
canagliflozin

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21
Q

cheapest drug options

A

metformin
SU
TZD

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22
Q

injectable formulations

A

insulin
GLP-1
pramlintide

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23
Q

SS scale adjustments

A

2 U every 50 starting from 150

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24
Q

inpatient glucose

25
hypoglycemic
<70
26
room temperature stability 3 days
opened alfreeza
27
room temperature stability 10 days
unopened alfreeza | humalog mix,humilin mix, pen
28
room temperature stability 14 days
humulin n, novolog mix pens, trulicity/adlyxin pens
29
room temperature stability 21 days
xultophy
30
room temperature stability 28 days
rapid acting, mix vials, r pen, lantus, basaglar, bydureon, soliqua
31
room temp stability 30 days
byetta, victoza
32
room temp stability 31 days
humulin r vials
33
room temp stability 40 days
humulin r u 500
34
room temp stability 42 days
novolin r, toujeo, levemir
35
room temperature stability 56 days
tresiba, ozempic
36
basal insulin dosing
0.1-0/2 U/kg/day or 10U/day
37
rapid correction factor
1800/TDD
38
regular correction factor
1500/TDD
39
correction dose
BG now- bg target/correction factor
40
TDD=
0.6 U/kg/day *based on TBW
41
insulin carb ratio for rapid
500/TDD
42
insulin carb ratio for regular
450/TDD
43
insulin pens that do not contain 100U/ml
humalog kwikpen:200 humulin R U 500 tresiba 200 toujeo 300
44
insulin pens that do not contain 3 ml
toujeo 1.5ML
45
alpha glucosidase inhibitor
acarbose (precose) | migilitol (glyset)
46
SU
glipizide (glucotrol) glimepride (amaryl) glyburide (glynase)
47
melitinides
repaglinide (prandin) | nateglinide (starlix)
48
TZDs
pioglitazone (actos) | rosiglitazone (avandia)
49
SGLT-2
canagliflozin (invokana) | empagliflozin (jardiance)
50
DPP-4
sitagliptin (januvia) | linagliptin (Trajenta)
51
Bile Acid Binding Resins
chlesevelam (whelcol)
52
dopamaine agonist
bromocriptine (cycloset)
53
GLP-1
exenatide (byetta) exenatide er (bydureon) liraglutide (victoza, saxenda) dulaglutide (trulicity)
54
amylin analog
pramlintide (sylmlinPen)
55
rapid acting insulin
aspart (novolog) lispro ( humalog, admelog) afrezza
56
short acting insulin
``` regular insulin (humulin R, novolin R) concentrated regular ( Humulin R U 500) ```
57
intermediate acting insulin
NPH insulin ( Humulin N)
58
long acting
determir (levemir) glargine (lantus, toujeo,basaglar) degludec (tresiba)