Diabetes (II) Flashcards

1
Q

Do not use if CrCl <30

A

metformin
SGLT-2
exenatide
glyburide

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2
Q

do not use if HF

A

TZD
alogliptin
saxagliptin

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3
Q

Do not use if peripheral neuropathy, PAD, ulcer

A

canagliflozin

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4
Q

Do not use if GI disorders

A

GLP-1

pranlintide

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5
Q

sulfa allergy, GPPD deficiency

A

SU

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6
Q

risk of lactic acidosis

A

metformin

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7
Q

risk of hepatotoxicity

A

tzd, alogliptin

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8
Q

risk of hypotension/dehydration/UTI/gentital infections

A

SGLT-2

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9
Q

risk of hyperkalemia

A

canagliflozin

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10
Q

risk of hypokalemia

A

insulin

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11
Q

risk of pancreatitis

A

DDP-4

GLP-1

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12
Q

risk of hypersensitivity reaction

A

SU
DPP-4
insulin

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13
Q

risk of ketoacidosis

A

SGLT-2

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14
Q

risk of bladder cancer

A

pioglitazone

dapagliflozin

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15
Q

risk of thyroid cancer

A

GLP-1

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16
Q

results in biggest decrease in A1c

A

insulin
metformin, SU
TZD

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17
Q

results in the greatest weight loss

A

SGLT2
GLP-1
pramlintide

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18
Q

results in hypoglycemia

A

insulin
SU
meglitinides
pramlintide

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19
Q

results in weight gain

A

insulin
SU
TZD
meglitinides

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20
Q

CVD benefit in patients with T2DM

A

empagliflozin
liraglutide
canagliflozin

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21
Q

cheapest drug options

A

metformin
SU
TZD

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22
Q

injectable formulations

A

insulin
GLP-1
pramlintide

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23
Q

SS scale adjustments

A

2 U every 50 starting from 150

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24
Q

inpatient glucose

A

140-180

25
Q

hypoglycemic

A

<70

26
Q

room temperature stability 3 days

A

opened alfreeza

27
Q

room temperature stability 10 days

A

unopened alfreeza

humalog mix,humilin mix, pen

28
Q

room temperature stability 14 days

A

humulin n, novolog mix pens, trulicity/adlyxin pens

29
Q

room temperature stability 21 days

A

xultophy

30
Q

room temperature stability 28 days

A

rapid acting, mix vials, r pen, lantus, basaglar, bydureon, soliqua

31
Q

room temp stability 30 days

A

byetta, victoza

32
Q

room temp stability 31 days

A

humulin r vials

33
Q

room temp stability 40 days

A

humulin r u 500

34
Q

room temp stability 42 days

A

novolin r, toujeo, levemir

35
Q

room temperature stability 56 days

A

tresiba, ozempic

36
Q

basal insulin dosing

A

0.1-0/2 U/kg/day or 10U/day

37
Q

rapid correction factor

A

1800/TDD

38
Q

regular correction factor

A

1500/TDD

39
Q

correction dose

A

BG now- bg target/correction factor

40
Q

TDD=

A

0.6 U/kg/day *based on TBW

41
Q

insulin carb ratio for rapid

A

500/TDD

42
Q

insulin carb ratio for regular

A

450/TDD

43
Q

insulin pens that do not contain 100U/ml

A

humalog kwikpen:200
humulin R U 500
tresiba 200
toujeo 300

44
Q

insulin pens that do not contain 3 ml

A

toujeo 1.5ML

45
Q

alpha glucosidase inhibitor

A

acarbose (precose)

migilitol (glyset)

46
Q

SU

A

glipizide (glucotrol)
glimepride (amaryl)
glyburide (glynase)

47
Q

melitinides

A

repaglinide (prandin)

nateglinide (starlix)

48
Q

TZDs

A

pioglitazone (actos)

rosiglitazone (avandia)

49
Q

SGLT-2

A

canagliflozin (invokana)

empagliflozin (jardiance)

50
Q

DPP-4

A

sitagliptin (januvia)

linagliptin (Trajenta)

51
Q

Bile Acid Binding Resins

A

chlesevelam (whelcol)

52
Q

dopamaine agonist

A

bromocriptine (cycloset)

53
Q

GLP-1

A

exenatide (byetta)
exenatide er (bydureon)
liraglutide (victoza, saxenda)
dulaglutide (trulicity)

54
Q

amylin analog

A

pramlintide (sylmlinPen)

55
Q

rapid acting insulin

A

aspart (novolog)
lispro ( humalog, admelog)
afrezza

56
Q

short acting insulin

A
regular insulin (humulin R, novolin R) 
concentrated regular ( Humulin R U 500)
57
Q

intermediate acting insulin

A

NPH insulin ( Humulin N)

58
Q

long acting

A

determir (levemir)
glargine (lantus, toujeo,basaglar)
degludec (tresiba)