Labour in the cell Flashcards
What is the function of the plasma membrane?
Selective permeability
What is the function of cytoplasm?
Hold shape of the cell
Transport molecules through the cell
What is the function of the nucleus?
Store and synthesise DNA
Control cell functions
What is the function of the smooth endoplasmic reticulum?
Make hormones
Store enzymes
Inactivate toxic substances
What is the function of the rough endoplasmic reticulum?
Make and distribute proteins (via ribosomes)
Edit polypeptides via enzymes
Send polypeptides to Golgi body for further editing
What is the function of ribosomes?
mRNA translation (make polypeptide chains)
Transport proteins
What is the function of mitochondria?
Make ATP
Replicate mDNA
What is the function of the Golgi body?
Modify, sort and concentrate proteins
What is the function of lysosomes?
Hydrolyse and endocytose cellular debris
What is the function of peroxisomes?
Create hydrogen peroxide by consuming oxygen (broken down by catalase)
What is the function of the cytoskeleton?
Hold shape of the cell
Aid transport of molecules through the cell
What is the function of microfilaments (element of the cytoskeleton)?
Hold cell shape
Resist tension
What is the function of microtubules (element of the cytoskeleton)?
Resist compression
Transport molecules
Compartmentalise cell
Form cilia
What is the function of intermediate filaments (element of the cytoskeleton)?
Connect skeleton together
Hold shape
What are the microfilaments made of?
Actin
What are the microtubules made of?
Tubulin
What are the intermediate filaments made of?
Keratin
Vimentin
How is fluidity in the plasma membrane formed?
Due to holes within the plasma membrane which are present where unsaturated elements of phospholipid tails are
Give an example of an outer leaflet phospholipid
Phosphatidylcholine
Give an example of an inner leaflet phospholipid
Phosphatidylserine
Name the types of phospholipid movement
Lateral mobility
Flip flop
What enzymes catalyses flip flop movement?
flipase
What does cholesterol help with in the plasma membrane?
Stiffening so not too fluid
What is the function of glycocalyx?
Barrier to cell
Protection from stress
Mediates cell to cell interactions
What are the types of proteins present in the plasma membrane?
Integral (AKA transmembrane)
Peripheral
Lipid anchor
What types of molecule can pass through the plasma membrane easily?
Hydrophobic, small and uncharged
What types of molecule can’t pass through the plasma membrane easily?
Hydrophilic, large, charged
Ions
What are the types of transport across the plasma membrane?
Passive (simple and facilitated)
Active
What are the types of vesicular transport?
Endocytosis - into the cell
Exocytosis - out of the cell
What are the types of endocytosis?
Phagocytosis - whole molecules
Pinocytosis - vesicles
Receptor-mediated endocytosis - whole molecules when a signal is received
What are the types of exocytosis?
Constitutive
Regulated - when a signal is received
What does glycolysis use and produce?
Uses: 2 ATP, 1 glucose
Produces: 4 ATP (net 2), 2 pyruvate, 2 NADH
Where does glycolysis take place?
Cytoplasm
Is glycolysis aerobic or anaerobic?
Anaerobic
What does the citric acid cycle use and produce?
Uses: 2 pyruvate (converted to Acetyl CoA)
Produces: 2 ATP, 6 NADH, 2 FADH2, 4 CO2
What does the conversion of pyruvate to Acetyl CoA produce?
2 NADH, 2 CO2
Where do the citric acid cycle and oxidative phosphorylation take place?
Mitochondrial inner membrane
Are the citric acid cycle and oxidative phosphorylation aerobic or anaerobic?
Aerobic
What does oxidative phosphorylation use and produce?
Uses: 10 NADH, 2 FADH2, 6O2
Produces: 32 ATP, 6 H20
What do the electron transport chain and chemiosmosis do within oxidative phosphorylation ?
Electron transport chain: reoxidisation of NADH and FADH2 causes movement of H+ ions over membrane
Chemiosmosis: creates ATP by moving NADH and FADH2 H+ ions back across the membrane via ATP synthase