LABORATORY RESULTS SECTION 2 Flashcards

1
Q

WHITE BLOOD CELLS

leukopenia (reduced WBC)

A

Infection, Bone marrow disorders, Autoimmune disease

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2
Q

WHITE BLOOD CELLS

leukocytosis (increased WBC)

A

Infection, Inflammation, stress

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3
Q

neutrophils

A

Infection, especially bacterial

Cigarette smoking

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4
Q

lymphocytes

A

Infection, especially viral
Stress
Allergy

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5
Q

monocytes

A

Infection, especially bacterial

Inflammation

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6
Q

eosinophils and basophils

A

Allergy

Parasitic infection

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7
Q

the differentials describe each type of WBC

A

as a % of the total WBC.
ex neutrophil is 85% of WBC. the absolute neutrophil count converts that percentage into a final #. so absolute neutrophil count would be 85% of WBC so .85 times the total # of WBC’s = 8.5

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8
Q

left shift

A

infectious situation. bands are increased in patient. this means body is responding to infectious process.

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9
Q

bands

A

immature neutrophils

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10
Q

segs

A

matured neutrophils

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11
Q

granulocytes

A

neutrophils, eosinophils, and basophils

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12
Q

low RBC

A

Iron deficiency, folate deficiency,

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13
Q

↓ Hgb/Hct

A

Anemia
Blood loss
Hemodilution
Chemotherapy

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14
Q

Thrombocytopenia (decreased platelets)

A

Infection

Beta-lactam antibiotics, sulfonamide antibiotics, vancomycin, heparin

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15
Q

Thrombocytosis (increased platelets)

A

Anemia, blood loss

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16
Q

CBC complete blood count

A
WBC
RBC
Hgb
Hct
Platelets
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17
Q

differentials

A
in addition to cbc 
Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils
18
Q

mean corpuscular volume (MCV)

A

red blood cell size

19
Q

Mean corpuscular hemoglobin (MCH)

A

mean hemoglobin content in each RBC

20
Q

Mean corpuscular hemoglobin concentration (MCHC)

A

mean conc of hemoglobin in RBC

21
Q

Red blood cell distribution width (RDW)

A

amount of red blood cell variation in volume and size

22
Q

Reticulocyte count

A

immature RBC

23
Q

MCV and MCH and MCHC and RDW determine

A

what type of anemia is occurring

24
Q

ferritin

A

iron storage protein

25
Total iron binding capacity (TIBC)
directly related to transferrin
26
international normalized ratio (INR)
time it takes for blood to clot | (PT patient/PT normal)^ISI
27
Activated partial thromboplastin time (aPTT):
measure of intrinsic and common clotting pathways | monitors heparin therapy
28
anti factor Xa
measure of ability to reduce factor Xa activity | monitors heparin therapy
29
D dimer
measure of fibrin degradation
30
PT INR is usually used to measure
warfarin therapy
31
Erythrocyte sedimentation rate (ESR):
indirect marker of acute phase reactants | early way of telling if you have inflammation
32
C-reactive protein (CRP):
marker of inflammation
33
procalcitonin
marker of inflammation, especially bacterial infection
34
Lactate dehydrogenase (LDH):
measure of tissue damage
35
high uric acid
gout, malignancy | Thiazide diuretics, calcineurin inhibitors
36
increased amylase
normalizes within 3-5 days - pancreatitis - salivary glands
37
increased lipase
normalizes within 2 weeks - pancreatitis - > Alcohol - > Delayed presentation
38
Urinalysis
color, clarity, volume, pH
39
anuria
Failure of kidneys to produce urine
40
oliguria
the production of abnormally small amounts of urine
41
hyaline
only found in healthy patients
42
surrogate endpoint
a laboratory measurement used as a substitute for a clinically meaningful endpoint that is a direct measure of how a patient feels, functions, or survives and is expected to predict the effect of the therapy