LABORATORY RESULTS SECTION 2 Flashcards

1
Q

WHITE BLOOD CELLS

leukopenia (reduced WBC)

A

Infection, Bone marrow disorders, Autoimmune disease

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2
Q

WHITE BLOOD CELLS

leukocytosis (increased WBC)

A

Infection, Inflammation, stress

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3
Q

neutrophils

A

Infection, especially bacterial

Cigarette smoking

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4
Q

lymphocytes

A

Infection, especially viral
Stress
Allergy

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5
Q

monocytes

A

Infection, especially bacterial

Inflammation

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6
Q

eosinophils and basophils

A

Allergy

Parasitic infection

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7
Q

the differentials describe each type of WBC

A

as a % of the total WBC.
ex neutrophil is 85% of WBC. the absolute neutrophil count converts that percentage into a final #. so absolute neutrophil count would be 85% of WBC so .85 times the total # of WBC’s = 8.5

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8
Q

left shift

A

infectious situation. bands are increased in patient. this means body is responding to infectious process.

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9
Q

bands

A

immature neutrophils

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10
Q

segs

A

matured neutrophils

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11
Q

granulocytes

A

neutrophils, eosinophils, and basophils

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12
Q

low RBC

A

Iron deficiency, folate deficiency,

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13
Q

↓ Hgb/Hct

A

Anemia
Blood loss
Hemodilution
Chemotherapy

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14
Q

Thrombocytopenia (decreased platelets)

A

Infection

Beta-lactam antibiotics, sulfonamide antibiotics, vancomycin, heparin

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15
Q

Thrombocytosis (increased platelets)

A

Anemia, blood loss

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16
Q

CBC complete blood count

A
WBC
RBC
Hgb
Hct
Platelets
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17
Q

differentials

A
in addition to cbc 
Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils
18
Q

mean corpuscular volume (MCV)

A

red blood cell size

19
Q

Mean corpuscular hemoglobin (MCH)

A

mean hemoglobin content in each RBC

20
Q

Mean corpuscular hemoglobin concentration (MCHC)

A

mean conc of hemoglobin in RBC

21
Q

Red blood cell distribution width (RDW)

A

amount of red blood cell variation in volume and size

22
Q

Reticulocyte count

A

immature RBC

23
Q

MCV and MCH and MCHC and RDW determine

A

what type of anemia is occurring

24
Q

ferritin

A

iron storage protein

25
Q

Total iron binding capacity (TIBC)

A

directly related to transferrin

26
Q

international normalized ratio (INR)

A

time it takes for blood to clot

(PT patient/PT normal)^ISI

27
Q

Activated partial thromboplastin time (aPTT):

A

measure of intrinsic and common clotting pathways

monitors heparin therapy

28
Q

anti factor Xa

A

measure of ability to reduce factor Xa activity

monitors heparin therapy

29
Q

D dimer

A

measure of fibrin degradation

30
Q

PT INR is usually used to measure

A

warfarin therapy

31
Q

Erythrocyte sedimentation rate (ESR):

A

indirect marker of acute phase reactants

early way of telling if you have inflammation

32
Q

C-reactive protein (CRP):

A

marker of inflammation

33
Q

procalcitonin

A

marker of inflammation, especially bacterial infection

34
Q

Lactate dehydrogenase (LDH):

A

measure of tissue damage

35
Q

high uric acid

A

gout, malignancy

Thiazide diuretics, calcineurin inhibitors

36
Q

increased amylase

A

normalizes within 3-5 days

  • pancreatitis
  • salivary glands
37
Q

increased lipase

A

normalizes within 2 weeks

  • pancreatitis
    - > Alcohol
    - > Delayed presentation
38
Q

Urinalysis

A

color, clarity, volume, pH

39
Q

anuria

A

Failure of kidneys to produce urine

40
Q

oliguria

A

the production of abnormally small amounts of urine

41
Q

hyaline

A

only found in healthy patients

42
Q

surrogate endpoint

A

a laboratory measurement used as a substitute for a clinically meaningful endpoint that is a direct measure of how a patient feels, functions, or survives and is expected to predict the effect of the therapy