Chronic kidney disease part 1 Flashcards
most common causes of ckd death
cardiovascular disease
i inch
2.54 cm
who is more susceptible to chronic kidney disease?
black pop > asian > white
definition of CKD (KDIGO)
Abnormality of kidney structure (commonly albuminuria)
OR
Abnormality of kidney function (commonly decreased GFR)
for > 3 months
staging g1 g2 g3a g3b g4 g5
GFR (mL/min/1.73 m^2)
> or equal to 90 (relatively normal GFR, evidence of known kidney damage)
60 - 89 (relatively normal GFR, evidence of known kidney damage)
45-59
30-44
15-29
< 15 (dialysis)
staging - this identifies cause of disease
a1
a2
a3
ACR (mg/g) / AER (mg/day)
<30
30 - 300
>300
GFR when considered in the absense of albuminuria (or any stage of albuminuria)
is correlated to adverse complications as dysfunction increases
gfr is a stronger predictor of clinical outcomes than
albuminuria
presentation of CKD
Asymptomatic
Functional signs and symptoms
- Fluid overload
- Electrolyte accumulation
- Uremia
acute vs chronic
acute
- Recent onset
- Marked oliguria or anuria
- Progressive daily increase in creatinine after initial recognition
chronic
- Small kidneys on radiography
- Evidence of renal osteodystrophy