Lab Tests

Question 1

What are the labs for SLE?

Answer 1

Anti-dsDNA and Anti-Smith

Question 2

What are the labs for ankylosing spondylitis?

Answer 2

HLA-B27 and CRP

Question 3

What are the labs for RA?

Answer 3

RF, ACPA

Question 4

What are the labs for Scleroderma?

Answer 4

Anti centromere → CREST
Anti-DNA Topoisomerase (Scl-70) → Diffuse Ssc
Anti-RNA-Polyermase III → Diffuse Ssc; renal crisis risk
Anti-beta-2-glycoprotein 1 → Ssc; micro vascular disease

Question 5

What are the labs for Sjogren’s?

Answer 5

Anti-Ro and Anti-La (anti-SSA and anti-SSB)

Question 6

What are the tests for Wegeners?
What are the tests for microscopic polyangitis?
What are the tests for Churg Straus?

Answer 6

cANCA
pANCA
pANCA

Question 7

Anti Sm →

Answer 7

SLE with mild dz

Question 8

Anti Ro and Anti La →

Answer 8

Sjogren’s

Question 9

Anti-DNA topoisomerase →

Answer 9

systemic sclerosis

Question 10

Anti-tRNA synthetase (Jo-1) →

Answer 10

poly or dermatomysotis

Question 11

Anti-SSA (Ro antibodies) →

Answer 11

neonatal lupus, Sjogren’s, high incidence of cutaneous vasculitis , subacute cutaneous lupus, primary biliary cirrhosis

Question 12

Anti-Centromere ANA →

Answer 12

only CREST

Question 13

Anti-nucleolar RNA →

Answer 13

Scleroderma or SLE

Question 14

If ↑ CRP + ↑ ESR →

Answer 14

inflammatory

Question 15

If ↑ CRP and ↓ ESR →

Answer 15

hypergammaglobulemia

Question 16

Anti-RNA-Polyermase III →

Answer 16

Diffuse Scleroderma and renal crisis