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Parasitology > [Lab] Prelim Oral Revalida > Flashcards

[Lab] Prelim Oral Revalida Flashcards

1
Q

Summarize the life cycle of E. histolytica

A

Cyst is ingested 👉 excystation in small intestine 👉 produces 8 trophozoites 👉 then go in the large intestine 👉 replicate by binary fission and feed on host cells 👉 encystation in intestinal lumen 👉 cysts are excreted in feces

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2
Q

MOT of E. histolytica

A

Hand-to-mouth ✋ 👄
Food or water contamination 🍔 🌊

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3
Q

Infective stage of E. histolytica

A

Mature cyst

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4
Q

Associated disease of E histolytica

A

Symptomatic Intestinalis amebiasis
- amebic colitis (diarrhea, anorexia)
- amebic dysentery (blood or pus or mucus in stool)

Symptomatic extraintestinal amebiasis
- amebic pneumonitis (fever, cough, liver infection)
- venereal amebiasis (penile, vaginal amoebiasis)

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5
Q

Diagnostic stage of E. histolytica

A

Trophozoite and cyst

  • direct wet preparation (stool, sigmoidoscopy material, hepatic abscess material)
  • culture (TYI-S33)
  • immunologic procedures (antigen test, indirect immunofluorescence)
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6
Q
A
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7
Q

Treatment for E histolytica

A

• asymptomatic
- paromomycin
- metronidazole (flagyl)

• symptomatic
- iodoquinol
- paromomycin

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8
Q

E hartmanni life cycle

A

Ingestion of cyst (direct contact, water, food) 👉 excystation in small intestine 👉 trophozoite go to colon and feed on intestinal contents 👉 encystation in large intestine 👉 cysts and trophozoites are excreted in feces

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9
Q

E hartmanni MOT

A

Fecal-oral route 💩 👄
Ingestion of contaminated food and water 🍔💦

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10
Q

Infective stage of E hartmanni

A

Mature cysts

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11
Q

Diagnostic stage of E hartmanni

A

Trophozoites and cysts

• stool analysis

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12
Q

Associated disease of E hartmanni

A

None, asymptomatic

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13
Q

Treatment of E hartmanni

A

None

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14
Q

E coli life cycle

A

Ingestion of mature cyst (water or food) 👉 excystation in intestine 👉 trophozoite go to large intestine and feeds on bacteria and debris 👉 encystation as they move to the colon 👉 cysts are excreted in feces

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15
Q

MOT of E coli

A

Ingestion of contaminated food and water 🍔💦

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16
Q

Infective stage of E coli

A

Mature cyst

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17
Q

Diagnostic stage of E coli

A

Trophozoite and cysts

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18
Q

Associated disease of E coli

A

None, asymptomatic

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19
Q

Treatment for E coli

A

None

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20
Q

E polecki life cycle

A

Ingestion of cyst (water or food) 👉 excystation in small intestine 👉 trophozoite feed on intestinal contents and multiply by binary fission 👉 encystation in large intestine 👉 cyst excreted in feces

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21
Q

E polecki MOT

A

Human to human 🤼
Pig to pig 🐖🐷

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22
Q

E polecki infective stage

A

Mature cyst

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23
Q

E polecki diagnostic stage

A

Trophozoites and cysts

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24
Q

E polecki associated disease

A

None, asymptomatic

Maybe diarrhea

25
Treatment of E polecki
Metronidazole Combination of metronidazole (flagyl) and diloxanide furoate (furamide)
26
27
Endolimax nana life cycle
Ingestion of mature cyst (food or water) 👉 excystation in intestines 👉 trophozoite feed on bacteria and reproduce by binary fission in intestinal lumen 👉 encystation occurs 👉 cysts excreted in feces
28
Endolimax nana MOT
Ingestion of contaminated food and water 🍔💦
29
Infective stage of Endolimax nana
Mature cyst
30
Diagnostic stage of Endolimax nana
Trophozoite and cyst Stool analysis
31
Associated disease of Endolimax nana
None, asymptomatic
32
Treatment for Endolimax nana
None
33
Iodamoeba butschlii life cycle
Ingestion of mature cyst (food, water) 👉 excystation in small intestine 👉 trophozoite feed on bacteria and debris in intestinal lumen 👉 trophozoite multiply by binary fission 👉 encystation occurs 👉 cysts excreted in feces
34
Iodamoeba butschlii MOT
Ingestion of contaminated food and water 🍔💦 Hand-to-mouth transmission ✋ 👄 Contaminated hog feces 🐖 💩
35
Infective stage of Iodamoeba butschlii
Mature cyst
36
Diagnostic stage of Iodamoeba butschlii
Trophozoite and cyst Stool analysis
37
38
Associated disease of Iodamoeba butschlii
None, asymptomatic
39
Treatment for Iodamoeba butschlii
None
40
E gingivalis life cycle
Infection through person-to-person contact (kiss, share utensils) 👉 trophozoites feed on bacteria and organic debris in oral cavity (gingival pockets) 👉 reproduce by binary fission 👉 remain in mouth
41
E gingivalis MOT
Kissing 💋 Droplet contamination (utensils)💧
42
E gingivalis infective stage
Trophozoites
43
E gingivalis diagnostic stage
Trophozoite • microscopic examination - mouth scrapings from gingival area
44
Associated disease of E gingivalis
None Recovered from patients with pyorrhea alveoaris
45
Treatment for E gingivalis
None
46
Naegleria fowleri life cycle
Trophozoites enter nasal mucosa during swimming 👉 trophozoite go to brain via olfactory nerves 👉 causes primary amoebic meningoencephalitis (PAM)
47
Naegleria fowleri MOT
Sniffing contaminated water 👃 💦 Contaminated dust
48
Naegleria fowleri infective stage
Trophozoite
49
Naegleria fowleri diagnostic stage
Trophozoite in Cerebrospinal fluid (CSF) • Microscopic examination of cerebrospinal fluid • culture: agar plates • other specimens: tissue and nasal discharge
50
51
Naegleria fowleri associated disease
• primary amoebic meningoencephalitis (PAM) (fever, meningitis) • kernig's sign (3-6 days death, inability to fully straighten leg when hip is flexed at 90 degrees)
52
Naegleria fowleri treatment
Amphotericin B Amphotericin B with rifampin or miconazole
53
Acanthamoeba spp life cycle
Enter through eye (contact lens) 👉 leading to severe keratitis Enter through respiratory system 👉 leading to granulomatous amoebic encephalitis (GAE)
54
Acanthamoeba spp MOT
Direct eye invasion 👁️ Through nasal passages 👃 Through ulcerated or broken skin
55
Acanthamoeba spp infective stage
Cysts and trophozoites
56
Acanthamoeba spp diagnostic stage
Trophozoite and cyst
57
Associated disease of Acanthamoeba spp
Granulomatous amoebic encephalitis Acanthamoeba keratitis
58
Acanthamoeba spp treatment
Sulfamethazine

Parasitology (4 decks)

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