Lab Haematology Flashcards

1
Q

What is the liquid that RBC’s are suspended in called?

A

Plasma

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2
Q

What is in the tube when blood is taken and collected? Why?

A

Anti-coagulant

So it doesn’t clot

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3
Q

What is the average adult volume of blood?

A

4.5-6 Litres

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4
Q

Name the 3 main cells of blood.

A

RBC
WBC
Platelets

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5
Q

Plasma makes up 55% of blood

A

TRUE

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6
Q

What are the 2 main types of WBC?

A

Granulocytes

Agranulocytes

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7
Q

Agranulocytes are…

A

Lymphocytes

Monocytes

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8
Q

Granulocytes are…

A

Neutrophils
Basophils
Eosinophils

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9
Q

List contents of plasma

A

Water (90%)
Proteins
Nutrients
Salts

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10
Q

What proteins are in plasma?

A

Albumins
Immunoglobulins
Clotting factors

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11
Q

What cells prevent bleeding?

A

Platelets

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12
Q

RBC’s have a nucleus once matured

A

FALSE

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13
Q

What is needed for RBC’s to mature and remove their nucleus?

A

Vitamin B12

Folic acid

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14
Q

Mean cellular volume is a measure of?

A

The size of RBC’s

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15
Q

Lack of iron leads to a reduction of what?

A

Haemoglobin

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16
Q

Low haemoglobin may suggest what condition?

A

Anaemia

17
Q

Microcytic cells become…

A

smaller

18
Q

Macrocytic cells become…

A

bigger

19
Q

Normocytic cells become…

A

Lol they don’t change size

20
Q

What causes microcytic cells?

A

Iron deficiency

Chronic blood loss

21
Q

What causes macrocytic cells?

A

Vitamin B12/folate deficiency

22
Q

What causes normocytic cells?

A

Acute blood loss

Anaemia of chronic/acute disease

23
Q

What 3 conditions may result in macrocytic cells without anaemia?

A
  1. Alcohol excess
  2. Liver disease
  3. Hypothyroidism
24
Q

What kind of reaction do basophils increase with?

A

Hypersensitivity

25
Q

What do monocytes increase with?

A

Chronic infections
Malignancy
Autoimmune disorders

26
Q

What is primary haemostasis?

A

Formation of platelet plug

27
Q

What is secondary haemostasis?

A

Formation of a fibrin clot

28
Q

What is fibrinolysis?

A

Breakdown of clot

29
Q

Platelets have a nucleus

A

FALSE

30
Q

What is a degradation product of fibrin?

A

D-dimers

31
Q

What does a coagulation screen measure?

A

The time taken to form a fibrin clot

32
Q

Clotting factors are produced in the liver. What can liver problems lead to?

A

Prolongation

Coagulation factor deficiencies

33
Q

What is plasma viscosity?

A

An index of changes in plasma proteins