Lab Haematology

Question 1

What is the liquid that RBC’s are suspended in called?

Answer 1

Plasma

Question 2

What is in the tube when blood is taken and collected? Why?

Answer 2

Anti-coagulant

So it doesn’t clot

Question 3

What is the average adult volume of blood?

Answer 3

4.5-6 Litres

Question 4

Name the 3 main cells of blood.

Answer 4

RBC
WBC
Platelets

Question 5

Plasma makes up 55% of blood

Answer 5

TRUE

Question 6

What are the 2 main types of WBC?

Answer 6

Granulocytes

Agranulocytes

Question 7

Agranulocytes are…

Answer 7

Lymphocytes

Monocytes

Question 8

Granulocytes are…

Answer 8

Neutrophils
Basophils
Eosinophils

Question 9

List contents of plasma

Answer 9

Water (90%)
Proteins
Nutrients
Salts

Question 10

What proteins are in plasma?

Answer 10

Albumins
Immunoglobulins
Clotting factors

Question 11

What cells prevent bleeding?

Answer 11

Platelets

Question 12

RBC’s have a nucleus once matured

Answer 12

FALSE

Question 13

What is needed for RBC’s to mature and remove their nucleus?

Answer 13

Vitamin B12

Folic acid

Question 14

Mean cellular volume is a measure of?

Answer 14

The size of RBC’s

Question 15

Lack of iron leads to a reduction of what?

Answer 15

Haemoglobin

Question 16

Low haemoglobin may suggest what condition?

Answer 16

Anaemia

Question 17

Microcytic cells become…

Answer 17

smaller

Question 18

Macrocytic cells become…

Answer 18

bigger

Question 19

Normocytic cells become…

Answer 19

Lol they don’t change size

Question 20

What causes microcytic cells?

Answer 20

Iron deficiency

Chronic blood loss

Question 21

What causes macrocytic cells?

Answer 21

Vitamin B12/folate deficiency

Question 22

What causes normocytic cells?

Answer 22

Acute blood loss

Anaemia of chronic/acute disease

Question 23

What 3 conditions may result in macrocytic cells without anaemia?

Answer 23

1. Alcohol excess
2. Liver disease
3. Hypothyroidism

Question 24

What kind of reaction do basophils increase with?

Answer 24

Hypersensitivity

Question 25

What do monocytes increase with?

Answer 25

Chronic infections Malignancy Autoimmune disorders

Question 26

What is primary haemostasis?

Answer 26

Formation of platelet plug

Question 27

What is secondary haemostasis?

Answer 27

Formation of a fibrin clot

Question 28

What is fibrinolysis?

Answer 28

Breakdown of clot

Question 29

Platelets have a nucleus

Answer 29

FALSE

Question 30

What is a degradation product of fibrin?

Answer 30

D-dimers

Question 31

What does a coagulation screen measure?

Answer 31

The time taken to form a fibrin clot

Question 32

Clotting factors are produced in the liver. What can liver problems lead to?

Answer 32

Prolongation | Coagulation factor deficiencies

Question 33

What is plasma viscosity?

Answer 33

An index of changes in plasma proteins