Lab Findings in Heart Disease Detection and Management

Question 1

3 Types of Natriuretic Peptides

Answer 1

Atrial, B-type and C-type

Question 2

ANP Description

Answer 2

28-AA peptide found in teh atrium of the heart

Question 3

BNP Description

Answer 3

32-AA peptide found mainly in the ventricles of the heart

Question 4

CNP Description

Answer 4

53- and 22-aa peptides found in the endothelium

Question 5

Cause of BNP Release and Correlation

Answer 5

Released in response to stretch/ increased volume in the ventricle.
BNP Correlates with LVEDP, NYHA Class and Objective HF diagnosis in pt’s 55 or older

Question 6

BNP Normal Levels

Answer 6

BNP < 100 pg/ml highly specific (90%) for NON-HF cause

Higher levels in renal failure, women & elderly

Question 7

Cardiac Enzymes (Troponins)

Answer 7

Troponin (I and T)
Felt to be specific to the heart
Released into bloodstream with myocyte necrosis