Lab Assays Flashcards
1
Q
Sensitivity
A
Goal is to avoid false negatives; SnNOut
2
Q
Specificity
A
Goal is to avoid false positives; SpPIN
3
Q
Organism Burden
A
Amount/Number of organism
4
Q
Sensitivity Situations
A
- Low Organism Burden
- Too Little Specimen
5
Q
Specificity Situations
A
- Potential detection of closely related organisms
- Low prevalence population
6
Q
Screening Testing
A
Testing for individuals without symptoms of disease.
- Biased in favor of sensitivity to avoid false negatives.
7
Q
Diagnostic Testing
A
Testing for individuals with symptoms of disease.
- Confirmatory testing usually involves more specific testing to avoid false positives.
8
Q
Blood Cultures
A
2 sets (1 set=2 bottles) of blood are drawn from two different body sites.
- When the results from both sets are the same => means the source of pathogenic organism was actually in the pt’s blood.
- When the results from one set is different from the other set => means one set was contaminated.
9
Q
Antigen Detection Test
A
Indicates the presence of the organism in the specimen.
10
Q
Antibody Detection Test
A
Indicates HOST responses to the organism.
- retrospective
- antibodies can take time to develop
11
Q
Nucleic Acid Amplification Tests (NAATs)
A
Testing that amplifies target molecules.
- most sensitive testing out of tests we learned.
- don’t need live organisms.
- can be obtained from urine samples.
