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BIOL1115 LAB > Lab 8 > Flashcards

Lab 8 Flashcards

1
Q

what is genetics?

A

study of molecular variation in organisms and the inheritance of that information

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2
Q

what are characteristics for good model organisms when studying genetics?

A

GROS
G- generation time is rapid
R - reproduction is quick
O - offspring are plentiful
S - space taken up is small

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3
Q

what is a monohybrid cross?

A

cross between two individuals that are both heterozygous for the certain phenotype

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4
Q

what is incomplete dominance?

A

when two alleles interact in a way that both are expressed (wavy hair is caused by Cc genotype)

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5
Q

what are polytene chromosomes?

A

large chromosomes that can be seen

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6
Q

what is a phenotype?

A

physical and observed expression of a particular trait/genotype

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7
Q

what is a genotype?

A

complete genetic set of an organism

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8
Q

what is the Law of Segregation?

A

homologous chromosomes separate in meiosis so that only one chromosome from each pair is present in each gamete

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9
Q

How do you determine the number of different gametes?

A

2^n
n= # of heterozygous genes

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10
Q

what is heterozygosity?

A

the presence of a heterozygous alle

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11
Q

what is the relationship between the number of gamete allele possibilities and the number of heterozygous alleles present?

A

the number of gamete possibilities increases as heterozygosity increases

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12
Q

why is human genetics difficult to study?

A
  1. long generation time
  2. small numbers of offspring
  3. immoral and unacceptable
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13
Q

what are pedigrees?

A

family trees that track certain traits, frequently those that cause diseases

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14
Q

how do you determine if traits are recessive or dominant?

A

look for mating where two parents with same phenotype and child with opposite phenotype

  1. affected parents and unaffected child, dominant trait
  2. unaffected parents and affected child, recessive trait (only possible if parents are heterozygous and child is homozygous recessive)
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15
Q

why should we approach a pedigree and assume any results of a cross are equally possible?

A
  • although one result may be less likely, the less likely one cannot be excluded as results are random
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16
Q

what are antibodies?

A

defensive proteins in blood that can recognize and bind to foreign substances

17
Q

what are antigens?

A

substances that elicit an antibody response

18
Q

what does Allele IA produce?

A

glycoprotein antigen A on RBC surfaces

19
Q

what does Alelle IB produce?

A

glycoprotein antigen B on RBC surfaces

20
Q

what are the characteristics of alleles IA and IB?

A
  • both are dominant - one copy is sufficient to express its phenotypic effect
  • both are codominant - both are expressed when both are present
21
Q

what happens to a person with Type A blood when it comes across Type B blood?

A
  • doesn’t produce Anti-A antibodies
  • produces Anti-B antibodies as it recognizes antigen B as foreign
22
Q

what happens to a person with Type B blood when it comes across Type A blood?

A
  • doesn’t produce Anti-B antibodies
  • produces Anti-A antibodies as it recognizes antigen A as foreign
23
Q

what happens to a person with Type AB blood when it comes across any blood?

A
  • doesn’t produce Anti-A or Anti-B antibodies
24
Q

what happens to a person with Type O blood when it comes across any blood?

A
  • produces anti-B and anti-A antibodies as it recognizes antigen A and antigen B as foreign
25
Q

what happens when antibodies attack the antigens on RBCS?

A

agglutination occurs, leads to blockage of small blood vessels

26
Q

how does one determine blood type?

A

mix blood in antiserum, solutions containing specific antibodies

27
Q

what is a positive response to an antiserum?

A

if agglutination occurs in an antiserum
(if a person’s blood tests positive with anti-A antisera that has anti-A antibodies, they have antigen A on their RBCs)

28
Q

how do you determine blood type of a father in paternity testing?

A
  1. determine possible genotypes of mother and genotype
  2. rule out any alleles the father could not have contributed
  3. determine which alleles the father would have had to contribute
29
Q

what do Rh+ alleles produce?

A

produces antigens on RBCs

30
Q

what do Rh- alleles produce?

A

nothing

31
Q

what happens when Rh- blood comes across Rh+ blood?

A

initial exposure - develop large numbers of antibodies against Rh+ blood
second exposure - agglutination

32
Q

why is type O negative blood the universal donor?

A

no reactions caused due to no antigens being produced by alleles

BIOL1115 LAB (8 decks)

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