Lab 3- Tissues and Integumentary Sys. Flashcards
What are the two distinct regions of the skin?
epidermis: composed of epithelium and an underlying connective tissue; and the dermis
What part is deep to the dermis?
subcutaneous layer or hypodermis; which is not considered part of the skin; consists primarily of adipose tissue
Epidermis
avascular; keratinized stratified squamous epithelium; consits of four distinct cells types and four or five distinct layers
What are the cells of the epidermis?
keratinocytes, melanocytes, dendritic cells, and tactile epithelial cells
Keratinocytes
most abundant epidermial cells; produce keratin fibrils; keratin is a fibrous protein that gives the epidermis its durability and protective capabilites; keratinocytes are tightly connected by desmoses
Melanocytes
spidery balck cells that produce the brown to black pigment called melanin; melanin protects against ultraviolet radiation (UVR)
Dendritic Cells
aka Langerhans cells; arise form the bone marrow and migrate to the epidermis; they ingest foreign sibstances and play a key role in activating the immune response
Tactile Epithelial Cells
occasional spiky hemispheres that, in combination with sensory nerve endings, form sensitive touch receptors located at the epidermal-dermal junction
How many layers are in thin skin?
4
How many layers are found in thick skin?
5; added stratum lucidum
What are the layers of the epidermis from deep to superficial?
stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum
Stratum Corneum
horny layer; the outermost layer consisting of 20-30 layers of dead, scalelike keratinocytes; they are constantly being exfoliated and replaced by the division of deeper cells
Stratum Lucidum
clear layer; present only in thick skin; a very thing transparent band of falttened, dead keratinocytes with indistinct boundaries
Stratum Granulosum
granular layer; a think layer named for the abundant granules its cells contain; these granules are 1) lamellar granules, which contain a waterproofing glycolipid that is secreted in the extracellular space; and 2) keratohylaine granules, which help to form keratin in the more superficial layers; at the upper border of this layer, the cells are beginning to die
Stratum Spinosum
spiny layer; serveral layers of cells that contain thick, weblike bundles of intermediate filaments made of a pre-keratin protein; the cells in this layer appear spiky because when tissue is prepared, the cells shrink, but their desmosomes hold tight to adjacent cells; cells in this layer and the basal layer are the only ones to receive adequate nourishment from diffusion of nutrients from the dermis
Stratum Basale
basal layer; a single row of cells immediately above the dermis; its cells are constantly undergoing mitosis to form new cells, hence it alternate name stratum germinativum; some 10-25% of the cells in this layer are melanocytes, which thread their processes through this and adjacent layers of keratinocytes; occasional tactile epithelial cells are also present in this layer
What are the two regions of the dermis?
papillary and reticular areas
Papillary Dermis
more superficial dermal region composed of areolar tissue; uneven and has fingerlike projections from it superior surface; abundant capillary networks allow nutrients and allow heat to radiate to the skin surface; pain receptors (free nerve ending) and touch receptors (tactile corpuscles) found here