Lab 1 Blood & Blood Tracing Flashcards
Blood & Blood Tracing
Neutrophils
appearance: light blue granules in acid based stain, lobed nucleus
percentage: 50-70% leukocytes
Basophils
appearance: deep blue granules from basic stain
percentage: less than 1% of leukocytes
Eosinophils
appearance: deep red granules in acid stain, bilobed nucleus
percentage: 2 - 4% of leukocytes
Monocytes
largest blood cell, leave bloodstream to become macrophages
appearance: kidney-shaped or oval nuclei
percentage: 3-8% of leukocytes
Lymphocytes
appearance: about the size of RBC, large spherical nuclei, thin rims of cytoplasm
percentage: 25-45% of leukocytes
Antigens
glycoproteins on cell membrane that can “potentially”. trigger an immune response (agglutinogens)
Antibody
protein that binds “specifically” to a particular antigen (agglutinins)
Type AB
Universal recipient: People with AB blood have no antibodies to A, B, or Rh antigens in their blood. AB antigens.
Type O
Universal Donor: no antigens presents so they can donate without transfusion issues, A and B antibodies.
Type A
A antigens, B antibodies
Type B
B antigens, A antibodies
Rh+
Rh antigens present, no antibodies
An Rh- mother has an Rh+ baby
Mother (Rh-):
Antigens: No Rh antigens
Antibodies: May develop anti-Rh antibodies after exposure during pregnancy or delivery.
Baby (Rh+):
Antigens: Rh antigens present on RBCs
her antibodies can cross the placenta and attack the baby’s Rh+ RBCs, leading to hemolytic disease of the newborn
Rh-
no Rh antigens, anti-Rh antibodies