L9 - Gram Positive Rods (pt. 4)

Question 1

Sulfa drugs act by inhibiting nucleic acid synthesis pathway

True or False?

Answer 1

True

Note: Fluroquinolones also do this (inhibit DNA gyrase)

Question 2

Causeous lymphadenitis in sheep and goats is caused by:

A. Corynebacterium psuedotuberculosis
B. Corynebacterium renale
C. Corynebacterium bovis
D. Corynebacterium ovis

Answer 2

A. Corynebacterium psuedotuberculosis

Note: Corynebacterium renale (group of bacteria that cause kidney infections, spinal nephritis bacteria in cattle). Any of these bacteria can cause any infections in any species; but some cause specific lesions

Question 3

Rhodococcus equi is an obligate intracellular pathogen

True or False

Answer 3

False

Note: Obligate means it needs a cell to survive and divide. BUT you can grow this in media

Question 4

A positive antibody titer to phospholipase D exotoxin of C. Pseudotuberculosis is a confirmatory diagnosis for internal forms of caseous lymphadenitis

True or False?

Answer 4

False

Question 5

Which of the following combination of antimicrobials are used for treating foal pneumonia caused by Rhodococcus equi?

A. Beta lactam/ aminoglycoside
B. Macrolide/ rifampin
C. Sulfa/ trimethoprim
D. Tetracycline/ fluroquinolone

Answer 5

B. Macrolide/ rifampin

Question 6

Appropriate term for drugs belonging to the sulfa group

A. Antibiotic
B. Antimicrobial agent
C. Antibacterial agent
D. Antiparasitic agent

Answer 6

B. Antimicrobial agent

Question 7

Name another antibiotic besides sulfa drugs that act by inhibiting nucleic acid synthesis pathway.

Answer 7

Answer: Fluroquinolones (inhibit DNA gyrase)

Question 8

What does Corynebacterium bovis do?

Answer 8

Answer: It causes skin lesions called hyperkeratosis in mice.