L25 - Spirochetes

Question 1

A 2yr old dog was presented with anorexia and vomiting. Below given is the hematology and blood chemistry analysis result. Analyze these values and answer the next few questions.

BUN > 130mg/dL (HIGH)
CREA > 13.6 mg/dL (HIGH)

Based on the blood chemistry results, the most concerning clinical problem this dog may have is:

A. Hepatic disease
B. Renal disease
C. Gastroenteritis
D. Dehydration

Answer 1

B. Renal disease

Note: The renal values where very high

Question 2

Hematolgy values indicate that this dog may have:

A. Anemia
B. Leukocytosis
C. Leukopenia
D. Leukemia

Answer 2

B. Leukocytosis

Note: w/ neutropenia

Question 3

Based on the hematology values indicate that an infectious process may be going on in this dog

True or False

Answer 3

True

Question 4

Based on the differential WBC count, this dog may have:

A. Bacterial infection
B. Fungal infection
C. Viral infection
D. Parasitic infection

Answer 4

A. Bacterial infection

Question 5

Which of the following disease should be in the top of your differential diagnosis list for this dog?

A. Leptospirosis
B. Lyme disease
C. Listeriosis
D. Legionellosis

Answer 5

A. Leptospirosis

Note: It can cause renal issues

Question 6

Which of the following tests will you request to maximize you diagnostic capability?

A. PCR on blood and urine
B. FA on urine and blood
C. Culture of blood, and MAT on serum
D. MAT and FA on serum
E. FA and/or PCR on Blood and Urine, and MAT on serum

Answer 6

E. FA and/or PCR on Blood and Urine, and MAT on serum

Question 7

Data #2

Microscopic agglutination test results on paired serum

This distribution of titers for various serovars shown above is most likely due to:

A. Infection w/ multiple serovars
B. Due to cross reactivity of antigens which is very common in initial stages of infection

Answer 7

B. Due to cross reactivity of antigens which is very common in initial stages of infection

Question 8

Phenomenon or presence of titers to multiple non-infecting serovard is known as

A. Hypersensitivity reactions
B. Paradoxical reactions
C. Paired titers
D. Cross reactivity

Answer 8

B. Paradoxical reactions

Note: Commonly happens when you do leptospros serology

Question 9

Sample A: MAT titer = 1/256
Sample B: MAT titer =1/4
Sample A has more antibodies than sample B

True or False

Answer 9

True