L23 - Mycobacteria Flashcards

1
Q

Properties of mycobacteria include ALL except:

A. Presence of mycolic acid in the cell wall
B. Positive acid fast staining
C. Presence of lipid compounds in the cell wall
D. Survival in the macrophages
E. Obligate intracellular pathogen

A

E. Obligate intracellular pathogen

Note: It is facultative intracellular pathogen; can be present inside and outside of the cell; they survive in macrophages.

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2
Q

Mycolic acid present in the cell wall of Mycobacteria, contribute to the virulence and acid fast staining property

True or False ?

A

True

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3
Q

Which of the following mycobacterium is a common cause of zoonotic tuberculosis?

A. M. tuberculosis
B. M. bovis
C. M. paratuberculosis
D. M. lepraemurium

A

B. M. bovis

Note: Bc of the wide host range

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4
Q

Which of the following is incorrect about mycobacterium infections

A. Induce granulomatous inflammation
B. Multinucleated macrophages are common in lesions
C. Caseous necrosis and mineralization may be present in the lesions
D. Humoral immunity helps in protecting from infections

A

D. Humoral immunity helps in protecting from infections

Note: You need cellular mediated immunity protects from infections. (all the other choices are correct)

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5
Q

Combination antimicrobial therapy is recommended in the treatment of tuberculosis to destroy multiple species of mycobacteria infecting a patient

True or False

A

False

Note: You need combination therapy to prevent the development of antimicrobial resistance

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6
Q

Which of the following is incorrect about Mycobacterium bovis

A. It can infect a wide range of host species
B. Transmission can occur through ingestion of unpasteruized milk and meat products
C. Cause lesions indistinguishable from M. tuberculosis infections in humans
D. Vaccination is the most effective way of controlling the disease

A

D. Vaccination is the most effective way of controlling the disease

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7
Q

Which of the following is LEAST likely to be infected with M. tuberculosis?

A. Human
B. Vervet monkey
C. Elephant
D. Duck

A

D. Duck

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