L8 Myopia Control Flashcards
what is myopia?
A refractive condition of the eye in which objects are focused in front of the retina.
It is a leading eye abnormality in Singapore & the most common in the world
what are some risks of myopia? why is myopia concerning?
-More common in Asians as compared to caucasians
-More near work= 2-3x risk
-The rate of progression increase in at a younger age.
-Genetics relations: 1 parent = 3x risk
-Both parents = 6x risk
it induces pathological changes
how does behavioral modifications control myopia?
Lifestyle changes!
Research has implicated near work as being connected with progression of myopia
how does ortho k control myopia?
Manipulation of peripheral defocus thereby stabilizing eye growth and myopia progression
Redistributions corneal epithelium cells to the mid-periphery while flattening the central cornea via a thinning of the epithelial layer
Some studies revealed that OK lens is effective in slowing down myopia progression
how do myopia control drugs work? what are 2 egs?
Drugs which prevent the eye from accommodating by blocking the ciliary muscle Eg:
Atropine
Pirenzepine (analogue of atropine)
what is the mode of action of atropine and pirenzepine?
Atropine:
Acts on M receptors
Pirenzepine:
Acts on M1 receptors. Found usually (but NOT exclusively) in neural cells like in the retina.
Muscarinic (M) receptors: There are 5 M
receptors (M1-M5)
what are the 3 diff concentrations of atopine? which is most effective?
Available in 3 different concentrations:
0.5%, 0.1%, 0.01% ( most recent )
Based on a recent study, 0.01% was found to be the most effective in controlling myopia progression with minimal side effects
