L8 - Growth (Paediatrics)

Question 1

what is human placental lactogen?

Answer 1

• produced by placenta
• breaks down fats from mother
• to provide fuel for growing baby

Question 2

human placental lactogen could lead to?

Answer 2

• insulin resistance and carbohydrate intolerance in mother

Question 3

SHOX gene

Answer 3

short stature homeobox.

• transcription factor
• responsible for skeletal development
• two functional copies in normal subjects

Question 4

Turners syndrome

Answer 4

• short stature ‘turner round you won’t see her’
• only have one X
• XO

Question 5

Achondroplasia

Answer 5

• genetic disorder
• dwarfism
• arms legs short, torso normallength

Question 6

Kleinfelters sign

Answer 6

• taller, less muscular body
• broader hips and longer legs
• weaker bones
• XXY
• low energy level
• smaller penis and testicles

Question 7

Marfan syndrome

Answer 7

• affects connective tissue
• disproportionately long legs
• high arched neck and crowded teeth