L8

Question 1

Genus Nicotiana, Family Solanaceae
• Native to __ • > 60 species
• Nicotiana tabacum - This species produces __ that is used today
• Traditional medicine used to treat: Asthma, Cough, Toothache, Sedative
• Tobacco leaf usage by Indigenous South Americans predates __ __ usage

Answer 1

Genus Nicotiana, Family Solanaceae
• Native to South America • > 60 species
• Nicotiana tabacum - This species produces tobacco that is used today
• Traditional medicine used to treat: Asthma, Cough, Toothache, Sedative
• Tobacco leaf usage by Indigenous South Americans predates coca leaf usage

Question 2

• 1492, Columbus in Cuba • “drinking smoke” - Indigenous peoples __ _ from leaves into nostrils
• 1500, _ _ introduces tobacco to France
• French Ambassador to Portugal • Ground leaves and seeds - _ for medicinal purposes • Active compound is _
• 1700, _ - Named genus after _

Answer 2

• 1492, Columbus in Cuba • “drinking smoke” -Indigenous peoples inhale smoke from leaves into nostrils
• 1500, Jean Nicot introduces tobacco to France
• French Ambassador to Portugal • Ground leaves and seeds - Snuff for medicinal purposes • Active compound nicotine
• 1700, Linnaeus - Named genus after Nicot

Question 3

Tobacco and United States colonization
• 1612, Virginia colony obtains seeds of _ _which becomes known as _ tobacco
• 1619, major export of American colonies to _
• Breaks __ tobacco monopoly
• Success of tobacco leads to increased _
• Changes agricultural approaches towards _

Answer 3

Tobacco and United States colonization
• 1612, Virginia colony obtains seeds of N. tabacum
which becomes known as Virginia tobacco
• 1619, major export of American colonies to England
• Breaks Spanish tobacco monopoly
• Success of tobacco leads to increased colonization
• Changes agricultural approaches towards large scale growth of
single crop

Question 4

IS Harvesting Tobacco Dangerous
• Green Tobacco Sickness:

• Symptoms:
• _
• _
• _
• _

Answer 4

yes
• Green Tobacco Sickness: Essentially nicotine poisoning, Occurs in contact with wet tobacco or
sweat

• Symptoms:
• Nausea
• Vomiting
• Headache
• Dizziness

Question 5

•_, major alkaloid in tobacco
• Stored in _
• Synthesized in _
• Derived from _
acid

Answer 5

•Nicotine, major
alkaloid in tobacco
• Stored in leaf
• Synthesized in root
• Derived from aspartic
acid

Question 6

Wilhelm Posselt
& Karl Reinmann
(Germany)
• isolated _ from
the _ plant and
identified it as a
_

Answer 6

Wilhelm Posselt
& Karl Reinmann
(Germany)
• isolated nicotine from
the tobacco plant and
identified it as a
poison

Question 7

alkaloid class for nicotine and its precursor

Answer 7

pyrrolidine

aspartic acid

Question 8

CNS response to nicotine

suppress _ reduce _ activate _

Answer 8

• Suppresses appetite, reduces anxiety, activates

dopaminergic reward system