L5 : erythrocytes , erythropoiesis, and anemia Flashcards
what is hematocrit value ( packed cell volume ) ?
percentage of RBCs in relation to total blood volume . normally about 45%
what is responsible for most of the buffering capabilities of blood ?
hemoglobin in RBCs
what is the most common type of hemoglobin in the adult human ?
hemoglobin A ( 2 alpha , 2 beta )
where are RBCs formed in children and where are they formed in adults ?
in infants , RBCs are formed in bone marrow cavities of all bones
in adults , RBCs are formed in red bone marrow which ramains only in sternum , vertebrae , ribs , base of skull and upper end of long limb bones
where are erythropoietin hormones secreted from?
85% from the liver , the remaining 15% are secreted from the kidneys
erythropoietin hormone secretion is stimulated by ?
Hypoxia due to: Hemorrhage High altitude Heart failure Anemia Lung disease
(letter H)
what is the full lifespan of RBCs?
120 days
what organ is known as the redblood cell grave yard?
spleen
what is increase in rbcs called?
polycythemia
