L10: Introduction to the physiology of CVS Flashcards
what is the difference between mild or chronic heart failure and severe heart failure ?
in mild heart failure the heart is still Abel to supply the vital organs , particularly the brain . something it cannot do when faced with severe heart failure .
what chamber of the heart works as a volume pump?
atria
what are the 2 trio-venticular values ? what are the 2 semilunar valves?
tricuspid and mitral valves
pulmonary and aortic
what causes heart valves to open and close ?
difference in pressure gradient
what are the functions of the AV fibrous tissue ring ?
acts as a cardiac skeleton : by serving as origin and insertion to the cardiac muscle fibers
electrical insulator :separating the arterial sheet of muscles from ventricular sheet of muscle . it is pierced by the atriventicular bundle (( AV bundle ) which is the only connection between atria and ventricles
what is the function of papillary muscles and chords tendinea ?
it prevents the opening of valves in the opposite direction
what are the functions of desmosomes and gap junctions in the intercalated discs of cardiac muscle ?
desmosomes are responsible for cell-cell cohesion and mechanical unity while gap junctions are responsible for electrical syncytium
what are junctional “ conductive “ tissue ?
(His bundle , bundle branches and purkinje fibers ) a specialized system of conduction of the excitation wave to the rest of the heart as quickly as possible
what nodal tissue has the highest firing rate ?
SA node , at 90-100 BPM
av node has a firing rate of 40-50
what other tissue can be responsible for auto-rhythmicity of the heart ?(other than SA and AV nodes )
His- purkinje system ( dormant pace makers ) have a much lower rate at 20-25 BPM
What has the slowest conduction ?
AVN
what is the significance of AVN delay ?
allows the atria to contact and empty their blood content into ventricle before ventricular contraction occurs
what is the significance of AVN block ?
protects ventricles against high ectopic atrial rhythm
what part of the heart has the highest conduction velocity ?
purkinje fiber endings of his bundle ( conducting pathway )
what is the significance of the very high conduction velocity of purkinje fibers ?
to ensure synchronous activation of both ventricles