L4: Pain and Chronic Illness Flashcards
pain definition
localized/ generalized unpleasant bodily sensation or complex of sensations that causes mild to severe physical discomfort and emotional distress and typically results from bodily disorder
Pain insensitivity/ congenital insensitivity to pain (CIP) / congenital analgesia
Defective gene SCN9A - involved in transmission of nociceptive signal
Can feel touch and sometimes temperature but not pain
experience of pain is…
Individualized and subjective
Situational
Cultural norms influence expression of pain and pain behaviors
measuring pain
verbal reports, simple self-report scales
McGill Pain Questionnaire
assesses pain intensity and character
multidimensional pain inventory
characteristics of pain, responses of others, interference with daily activities, mood…
pain behaviors
facial and audible expressions, posture and gait, negative affect, avoidance of activity
physiological measure of pain
no actual measure
Muscle tension, skin temperature, and HR show some relation to pain
acute pain
normally brief, adaptive
chronic pain
over moths/years, no adaptive reason or benefit
pre-chronic pain
between acute and chronic
chronic recurrent pain
alternating between having and not having pain
order of nociception
transduction –> transmission –> modulation –> perception
transduction
stimuli activating nerve endings
transmission
traveling of information through the nervous system
modulation
process of alterations in the pain signals along the transmission pathway of pain
nociceptors
neurons that sense painful stimuli, subtype of neurons capable of sensing other sensations like touch or pressure
somatic pain
located on the surface of the body
visceral pain
internal organs
3 types of fibers for nociception
A-delta, C, A-beta
A-delta fibers
small, myelinated
rapid transmission of initial and sharp pain (mechanical and thermal)
C fibers
unmyelinated fibers
transmit secondary, dull, or aching pain
A-beta fibers
large diameter myelinated
information about pressure and vibration
where does info for pain go from spinal cord?
to reticular formation and thalamus
a-delta fibers where do they go in the brain
somatosensory cortex
homunculus
size of cortex proportional to the sensitivity of that part of the body
referred pain
when pain is experienced in a part of the body other than the site where stimulus originates. - identifying location less distinct on the inside
Gate Control Theory and Pain Modulation
Structures in spinal cord act as a gate that can open and close → modulating the sensory input that the brain interprets as pain
Physical, emotional and cognitive factors can all impact modulation
Ascending Pathways in Gate Control Theory
signals from periphery can open and close gates (rubbing injuries) → activates afferent touch neurons or Abeta fibers, occupy the same pathway through spinal cord, interfere with afferent pain signals