L4 Genitourinary Flashcards

1
Q

What is the PTs role in GU disorders?

A

-recognize S/S of GU dysfunction
-understand how GU disorders impact rehab
-follow guidelines for interventions
-recognize common referral of pain areas of GU

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2
Q

Normal age related changes of GU system

A

-Decreased blood flow to kidneys
-Increased volume of urine and decreased bladder capacity
-shift toward nocturnal urine production

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3
Q

Hyponatremia

A

low level of sodium in the blood

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4
Q

Functions of kidneys

A
  1. excretion of cellular waste productions
  2. regulation of blood volume
  3. electrolyte regulation
  4. Acid-base regulation
  5. Arterial BP regulation
  6. EPO secretion
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5
Q

Common S/S of genitourinary pathology

A

Pain
Change in voiding habits

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6
Q

Pain (S/S of genitourinary pathology)

A

Varies according to origin

Pain generally described as wave-like, burning, or dull ache in abdomen, back, buttocks

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7
Q

Innervation of urinary system

A

T10-S4

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8
Q

Kidney Innervation

A

T10 to L1
Pain referral can be lumbar spine, upper abdomen
Will be the same side as the affected kidney

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9
Q

Ureter Innervation

A

T11-L2, S2-S4
Pain referral can be groin, upper/lower abdomen, scrotum, medial/proximal thigh, thoracolumbar region

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10
Q

Urinary Bladder Innervation

A

T11-L2, S2-S4
Pain referral can be in sacral apex, suprapubic region, thoracolumbar region

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11
Q

Change in voiding habits (s/s of pathology)

A

Urinary frequency
Urinary urgency
Nocturia
Polyuria
Oliguria
Dysuria
Hematuria
Decreased force of urinary flow
urinary incontinence
dyspareunia

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12
Q

Urinary frequency

A

of times a day
lower UTI

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13
Q

Urinary urgency

A

how much you need to pee
lower UTI

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14
Q

Nocturia

A

night urination
diabetes, heart failure

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15
Q

Polyuria

A

> 2.5 L per day
increased fluid intake, diabetes, chronic kidney disease

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16
Q

Oliguria

A

<400 ml a day
dehydration, renal failure

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17
Q

Anuria

A

<100 ml a day
dehydration, renal failure

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18
Q

Dysuria

A

painful
lower UTI

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19
Q

Hematuria

A

must report to MD ASAP
blood in urine
traumatic foley catheter, renal disease, cancer

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20
Q

Decreased force of urinary flow

A

prostate enlargement, urethral obstruction

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21
Q

Urinary Incontinence

A

inability to control voiding
SCI, dementia, CNS issues

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22
Q

Dyspareunia

A

pain during intercourse
more common in women
endometriosis, UTI, post menopause

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23
Q

Diagnostic tests for GU system pathology

A

Urinalysis
Creatinine Tests
Blood Urea Nitrogen

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24
Q

Urinalysis

A

Looks at color, odor, pH, specific gravity, absence of certain materials

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25
Urine color
varies from almost colorless to dark yellow depends on fluid, supplement, dietary intake
26
Urine odor
should not be strong (normal)
27
Specific Gravity
a measure of solutes in the urine should be 1.002 to 1.028
28
pH of urine
4.6 to 8.0
29
Urine should have an absence of
glucose, ketones proteins Hb/RBcs Bilirubin WBCs, bacteria
30
Glucose/Ketones in urine indicates
diabetes or keto diet
31
Proteins in urine indicates
GFM damaged, kidney disease
32
Hb/RBCs in urine indicates
cancer, excessive exercise
33
Bilirubin in urine indicates
live or bile duct problems
34
WBCs/bacteria in urine indicates
infection
35
Plasma Creatinine
Increased levels are indicative of decreased renal function
36
Creatinine Clearance
24 hr urine test, approximates GFR decreased Cr clearance is indicative of decreased renal function
37
Blood Urea nitrogen
increased BUN indicates: decreased renal function or fluid intake, increased muscle catabolism, increased protein intake, acute infection To implicate decreased renal function, BUN levels need to be correlated with plasma Cr levels
38
Mental status and BUN
alterations in BUN and creatinine levels may lead to alteration in patients mental status
39
X-rays are used to diagnose
kidney stone
40
IVP
blood flow
41
Cystoscopy
inspection of inside of bladder
42
Uroflowmetry
force of flow test
43
Radioisotope studies
diagnosis of kidney function mostly used for those that need to receive a kidney
44
Ultrasonagraphy
shape of kidney
45
UTI
infection within the urinary tract
46
Lower UTI
bladder and/or urethra
47
Upper UTI
kidneys and/or ureters
48
Epidemiology and Risk Factors for UTIs
-highest incidence in individuals in skilled nursing/extended care facilities -most common is urinary catheterization -Increased age, diabetes, sexually active females
49
Clinical presentation of UTI
altered mental status, shortness of breath, nausea/vomiting
50
Relationship to falls and UTI
more likely to fall with altered mental status
51
Increased age and UTIs
lower immune system, decreased personal hygiene, increased sedentary time
52
Diabetes and UTI
decreased immune response, increased bacteria, neuropathy
53
Pathogenesis of UTI
usually gram-negative bacteria ascending into the urinary tract from the urethra
54
Changes in voiding habits and UTI
frequency, urgency, dysuria, nocturia, dyspareunia cloudy, bad-smelling urine, or hematuria
55
Pain and Lower UTI
generally sudden onset of symptoms hallmark: dysuria
56
Upper UTI pain
typically gradual onset and systemic symptoms like fever, chills, malaise
57
general UTI pain
suprapubic, lower abdomen, groin, flank or back pain, shoulder pain possible
58
Shoulder strap pain
infectious agents and/or inflammatory mediators can diffuse locally and activate afferent endings in diaphragm visceral pain can be referred to shoulder pain due to the convergence of sensory neurons on the same group of dorsal horn neurons in spinal segment
59
Insidious onset of back pain complaints
make sure to ask about history of recent infection ask about changes in voiding habits, systemic S/S
60
Dx and Tx of UTI
Dx: History and urinalysis Tx: increased hydration, ABX Cranberry juice is statistically insignificant for treatment, and does not prevent
61
Pyelonephritis
infectious, inflammatory disease presumed to be caused by bacterial invasion of renal parenchyma Can be acute or chronic
62
Acute Pyelonephritis
most common cause is backwards flow of infected urine from bladder into upper urinary tract. often called ascending UTIs sometimes caused by blood borne pathogens
63
Chronic Pyelonephritis
kidneys become increasingly damaged due to repeated urinary infections can lead to scarring and loss of kidney function
64
Acute CP of Pyelonephritis
fever, chills, flank pain pain over costovertebral angle urinary frequency, dysuria, suprapubic discomfort physical findings can vary
65
Chronic CP Pyelonephritis
weakness, loss of appetite, HTN, anemia, protein and blood in urine
66
Pyelonephritis pain referral
flank
67
Pain referral areas of kidneys
ipsilateral for involved kidney
68
Kidney Stones
renal calculi or lithiasis 3rd most common GU disorder Can be in the urinary tract or kidneys Generally due to increased blood concentration and urinary excretion, infection can cause urinary obstruction
69
Composition of kidney stones
Dietary intake can impact reoccurrence Calcium/calcium oxalate= 75% Struvite = 15% Uric acid = 6% Cystine = 2%
70
Kidney Stones RF
30s-50s males excessive calcium, oxalate, purines dehydration
71
CP of kidney stones
HALLMARK COMPLAINT: abrupt pain associated with urinary tract obstructions, known as renal collic pain starts with stone leaves kidney. Generally abrupt onset
72
Kidney stones pain referral
L side
73
Dx Kidney Stones
urinalysis, looking for hematruia, infection, crystals. Can identify location of stones with IVP or CT
74
Tx of kidney stones
time, plus pain meds, hydration, ABX if needed extracorpreal shock wave therapy (ESWL)
75
Prevention of kidney stones
needed for high rate of recurrence hydration, dietary change (specifically spinach to decrease oxalate)
76
Glomerulonephritis
Group of disease that damages glomerular portion of the kidney condition accounts for 50% of pts requiring dialysis
77
RF for chronic glomerulonephritis
diabetes systemic lupus HTN
78
Many types of glomerulonephritis result from
immunologic problems !! drug toxin effects vascular diseases systemic disorders
79
Patho glomerulonephritis
Immune: immune complexes form in the circulation and get trapped in membrane, producing inflammatory reaction and histological changes vascular: capillaries become permeable, leading to proteinuria, hematuria, edema
80
CP of Glomerulonephritis
HTN proteinuria, pyuria, hematuria edema (albumin pulls water towards it)
81
Dx and Tx of Glomerulonephritis
Dx: urinalysis, HTN Tx: SAIDs, dietary changes, dialysis, renal transplant. Treatment of primary disease!
82
Tips for working with pts with glomerulonephritis
pts with DM, SLE, hepatitis, HTN, vasculitis have higher chance of chronic glomerulonephritis be alert to NEW edema and HTN ask about hematuria and oliguria, pts are often on diuretics call primary physician to report new S/S
83
ADRs of Diuretics
muscle weakness or cramps, fatigue, nausea, headache, dizziness, orthostatic hypotension, hypokalemia
84
Chronic Kidney Disease
progressive loss of renal function with permanent loss of nephrons due to multiple causes that continues to worsen even after causes are removed deterioration of kidney function is variable >30 mi americans are affected
85
RF of Chronic Kidney Disease
1. leading causes of new cases are DM (44%) and HTN (27%). Higher incidence in african americans 2. Overconsumption of NSAIDs 3. Age >65
86
CP of Chronic Kidney Disease
5 stages, s/s depend on severity and rapidity of failure, each stage is defined by eGFR fatigue, weight loss, metallic taste in mouth, nausea, pruritus
87
End stage renal disease
<15% of kidney function
88
Neuromusculoskeletal CP of Chronic Kidney Disease
mental dullness renal osteodystrophy, bone demineralization muscle, joint, bone pain extraskeletal calcification restless leg syndrome
89
Cardiovascular CP of Chronic Kidney
dyspnea, orthopnea edema HTN pericardial chest pain (nerves get bugged by edema)
90
Renal osteodystrophy
1. Kidney failure, decreased GFR, calcitriol 2. Secondary hyperparathyroidism, altered calcium set point 3. Gut absorption of Ca, decreased calcium absorption, increased phosphate retention 4. Bone remodeling, bone resorption Altered set point of blood calcium, it all causes increased mobilization of calcium into blood. hyper phosphate in blood
91
Dx of Chronic Kidney Disease
S/s Bun and Cr values (from eGFR) imaging serum PTH
92
Prognosis of Chronic Kidney Disease
Mortality rate of those >65 yr on dialysis is 7x that of age matched norms not on dialysis People >60 year who start dialysis have life expectancy of 5 yrs
93
Tx options for Chronic Kidney Disease
Conservative: HTN tx, dietary changes, anemia control, calcitriol meds. For everyone, every stage End stage: renal replacement, dialysis, transplant
94
Functions of Vitamin D
Active form of vitamnin D = CALCITRIOL Promotes mineralization of new bone increases calcium and phosphate absorption from gut stimulates calcium, phospahte reabsorption overall result of Vit D: increased plasma concentrations of Ca and phosphate
95
Renal Replacement
dialysis renal transplant Kidneys comprise 2/3 of organ transplant waiting list median waiting time is 3.6 years
96
Dialysis outcomes
71% unemployment little improvement in survival after dialysis no significant improvement in health related QOL
97
Exercise training in adults with CKD
improves BP control and lipid profiles improve glucose metabolism increase hematocrit and hemoglobin resistance training helps with bone density increase functional capcity
98
Research and CKD exercise
Benefits of exercise for CKD 26% decrease in use of antihypertensive meds after 3 months of cycling during dialysis $885 savings annually combined aerobic and resistance is the best for those with CKD
99
Why is exercise not encouraged for those doing hemodialysis
lack of awareness of benefits fear that it will cause harm
100
ACSM Guidelines for CKD
20-60 min of continuous activity 3-5 days a week can use 3-5 min bouts Resistance: 65% to 75% of 1 RM. Make sure to estimate, don't perform
101
No exercise with CKD if
BP >200/100 mmHP Serum K> 5 mEq WBC <5000 or 10000 w/fever Hct <25% or Hb <8 Platelets <20,000
102
AV fistula and exercise
be alert to infection risk hand-washing is essential do not measure BP on UE avoid placing weight or pressure on the fistula
103
Potassium normal value
3.7 to 5.1
104
RPE and Dialysis
use it to guide exercise intensity because HR is unreliable for this population aim for 9-13, talk but not sing
105
Exercise during dialysis
perform during first half to avoid hypotensive episodes pedaling and stepping devices are common don't exercise arm with permanent AV access continuous peritoneal dialysis might require fluid to be drained before exercising
106
Exercise AFTER dialysis
generally wait 2 hours after dialysis, due to fatigue
107
Renal Cell carcinoma
occurs in epithelial cells lining the kidneys not common cancer, but common KIDNEY cancer has four stages incidence is rising, peak is 60-70 year of age, men.
108
RF for RCC
smoking, obesity, increased red meat, decreased fruit/veggie consumption, chemical occupational exposure increase risk
109
CP of RCC
hematuria flank pain palpable abdominal mass
110
Staging vs Grading
Grading = histologic differentiation Staging = degree of spread
111
RCC Tx and Prognosis
Tx: surgery has better results than radiation Prognosis: needs to be caught early for surgery to be effective
112
Tip for PTs with RCC
if pt complains of new unexplained abdominal flank, back pain, sternal pain, cough or hematuria, contact PCP immediately
113
Normal aging and male reproductive system
1. shrinkage of testes 2. thickening of seminiferous tubules (decreased sperm production) 3. Enlargement of prostate gland, can double in size 4. Decreases in plasma testosterone level (loss of muscle, changes in bone density)
114
Sample questions to screen for GU disorders in men >50 yr of age
1. Urinary frequency/nocturia 2. Problems stopping/starting urination 3. Weak urine flow 4. Bladder never completely empty
115
Prostatitis
(young man condition) inflammation of prostate gland, can be acute or chronic. PTs are more likely to encounter pts with chronic prostatitis
116
Epidemiology and RF Prostatitis
Prevalence higher in men <40 yrs old Lower UTI Urinary catheterization multiple sex partners strong vibrations
117
Pathogenesis of Prostatitis
4 categories of prostatitis most common type is chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) causes are urine reflux, pelvic floor dysfunction
118
Chronic Prostatitis CP and DX
CP: low back and perineal pain. Pain w/prolonged sitting, voiding problems, sexual dysfunction Dx: urinalysis, digital rectal exam, differentiated from BPH and prostate CA by presence of PAIN
119
Chronic Prostatitis Referral Pain
low back and perineal pain
120
Prevention and Tx Options of Prostatitis
Prevention: decrease time in seated position. try different bike seats Tx: anti inflammatories, ABX, relaxants. PT (biofeedback, stretching)
121
Benign Prostatic Hyperplasia
age related nonmalignant enlargement of prostate gland Men >50 yr of age Moderate intake of alcohol has a decreased risk
122
Pathogenesis of BPH
unknown, maybe hormonal changes multiple nodules comprised of proliferating cells progressively narrow the urethra
123
BPH CP
decreased force of urinary flow urinary frequency, nocturia untreated progression, UTI, bladder wall changes, hydroureter
124
Dx of BPH
history uroflowmetry palpation
125
TX of BPH
Monitoring Surgery = TURP, resection of prostate Common meds: alpha reductase inhibitors (shrinks prostate), alpha adrenergic blockers (relaxes smooth muscle)
126
ADRs of alpha adrenergic blockers
tachycardia dizziness orthostatic hypotension increased risk of falls
127
Testicular Cancer
young man diseases abnormal, rapid, invasive growth of malignant cells in testicles most common cancer in males 15-35
128
RF of Testicular Cancer
past medical history of undescended testicles, abnormal development, previous testicular cancer family history caucasian
129
CP of Testicular Cancer
1. enlargement, lump, swelling of testicle 2. pain or feeling of heaviness in scrotum 3. Dull ache in back/lower abdomen (may be ONLY symptom >20% of cases) 4. Dyspnea 5. Gynecomastia, excessive breast tissue
130
Dx, Tx, Prevention of Testicular Cancer
Dx: urologic history and exam, painless mass in testicle in key sign Tx: chemotherapy, radiation, ectomies Prevention: testicular self exam every 6 months, early detection
131
Testicular cancer pain referral
In males with this referral pattern with no mechanical source: 1. ask about testicular self-exam 2. Assess supraclavicular lymphadenopathy 3. Perform iliopsoas test 4. Refer to MD
132
Menopause
transition when ovaries stop releasing eggs, menstrual activity decreases and eventually ceases estrogen and progesterone decrease, 1 year without menstruation occurs age 50
133
Changes with menopause
labia atrophy changed libido hot flashes, mood changes, sleep disturbances decrease in pelvic muscle tone
134
Endometriosis
endometrial tissue becomes implanted outside uterus; most commonly implants form on fallopian tubes, ovaries, or tissue lining pelvis
135
RF of Endometriosis
women of childbearing age w/out children early menarche, short menstrual cycles, long menstrual period family hx
136
Pathogenesis of Endometriosis
causes is unknown, roles suggested for hormones and immune system Common theory: mentrual blood containing endometrial cells is retrogradely flushed back through tubes into pelvic caivty endometrial cells form implants throughout the body
137
CP of Endometriosis
DYSMENORRHEA, DYSPAREUNIA, INFERTILITY excessive bleeding, pain, symptoms vary on growth
138
Dx of Endometriosis
the classic triad laparoscopy/laparotomy
139
Tx of Endometriosis
No cure. Goal is pain relief and preservation of fertility NSAIDs, surgery, hyterectomy
140
Endometriosis Referral of Pain
if pain is present regardless of sexual position, pain source is less likely to be a joint dysfunction
141
Endometrial Cancer
cancer of uterine lining most common cancer of female organs incidence peaks in 60-70 yrs old
142
RF of Endometrial cancer
increasing age obesity increased level of estrogen inactivity
143
CP of endometrial cancer
abnormal bleeding abdominal/LE edema
144
Dx and Tx of Endometrial Cancer
surgery hysterectomy salpingo-oophorectomy hormonal therapy radiation usually diagnosed early
145
Cervical Cancer
cancer that forms in cervix pap smears help to control the amount of cases HPV is the primary cause
146
Dx and Tx of Cervical Cancer
dx: pap smear tx: based on stage of disease. Pre would be excision, laser. Later would be surgery, chemo, radiation
146
Pathogenesis and CP of Cervical Cnacner
HPV turns of cells tumor suppressing genes, allowing abnormal changes in cervical epithelium to perpetuate CP: early stages are asymptomatic, advanced are abnormal bleeding, bowel bladder problems
147
Ovarian Cancer
usually diagnosed late malignant neoplasm located on the ovaries fairly uncommon but leading cause of death in female cancers. Usually dx when it has metastizied
148
RF of OVarian Cancer
more cycles, more risk age >40 year never breast fed family history of breast, ovarian, colon
149
Pathogenesis of Ovarian Cnacer
unknown cause correlated with number of times a woman ovulates spreads locally to pelvis, abdominal cavity, bladder can spread to lymph nodes
150
CP of Ovarian Cancer
often vague and nonspecific sense of pelvic heaviness vague lower abdominal bloating unexplained back pain that worsens over time gait disturbance due to brain metastases
151
Dx and Tx of Ovarian Cancer
Dx: screening test, pelvic exam that can show edema in perionetal cavity Tx: surgery, chemo. Low survival rate due to being diagnosed late
152
PT and Ovarian Cancer
due to risk of recurrence, PT should note gait changes
153
Ectopic Pregnancy
implantation of pregnancy in any location other than the uterus, often in fallopian tube
154
RF for ectopic
things that disrupt fallopian tube structure STDs, prior tubal surgery, IUD, history, pelvic inflammatory disease
155
Pathogenesis of Ectopic
dealyed ovum transport fertilization and implantation occurs in tube pregnancy outgrown blood supply possibility of ruptured fallopian tube
156
CP of Ectopic
variable, delayed or slight vaginal bleeding sudden, sharp, stabbing pain
157
Ectopic pain referral
emergency call to physician is warranted
158
Dx and Tx of Ectopic
Dx: pelvic ultrasound, elecated hCG, laparoscopy Tx: medication, removal of egg