L38 transplant immunology Bailey

Question 1

Orthotopic

Answer 1

transplaning to the same anatomic site

Question 2

Heterotopic

Answer 2

transplanting to different anatomical site

Question 3

Transfusion

Answer 3

transfer circulating cells from one individual to another

Question 4

Autologous graft

Answer 4

Graft from and to the same person

Question 5

Syngeneic graft

Answer 5

Graft transplanted between genetically identical indivudals

Question 6

Allogenic graft

Answer 6

Graft transplanted between genetically different individuals

Question 7

Reason for mismatch

Answer 7

MHC

Question 8

Indirect alloantigen recognition

Answer 8

Recipient APC engu

Question 9

Rapamycin

Answer 9

Blocks lymphocyte proliferation by inhibiting IL-2 signaling

Question 10

Anti-CD3 monoclonal antibody

Answer 10

Depletes T cells by binding to CD3 and promoting phagocytosis

Question 11

Anti-IL-2 receptor

Answer 11

Inhibits T cell activation by blocking IL-2 binding

Question 12

CTLA-4-Ig

Answer 12

Inhibits T cell activation by blocking B7 costimulator bindign to CD28

Question 13

M1 activation

Answer 13

IFN-Gamma

Question 14

M2 activation

Answer 14

IL-1
IL4
IL13

Question 15

How do CD8 cells kill?

Answer 15

They kill the cell with the virus in it not the actual virus