L2W3 CP & Dx TB Flashcards
Causative organism tb?(typical/atypical)
Typical:
-Mycobacterium TB (human type), Bovis & Africanum
Atypical:
-Pulmonary/lymph node(occasion)
-in pre-existing lung dis/suppress immune
TB bacilli char?
Xmotile, xform spore,xcapsule, acid fast & alcohol
Susceptible to:
- Direct sunlight(lethal)
- Heat(1 min boil)
- Phenol 4% & alcohol 70%
- UV radiatiom
Type tb? (2)
1ry TB(child) 2ry/reinf/postprimary(adult)
Component 1ry TB? (3)
- Ghon’s focus(TB granuloma)
- Lymphangitis
- TB lymphadenitis
Fate 1ry complex?(5)
- Heal wo cp(90%)
- Spread(10%)
- TB bronchopneumonia
- Miliary TB
- TB bronchitis
Symptom 1ry TB? (4)
- Asymp(major)
- Failure thrive, anorexia, fever
- Cough
- Expectoration(rare)
Sign 1ry?(5)
- Debilitation(severe)
- Crepitations
- Wheeze
- D’espine sign
- Sign segmental, lobar consolidation/ collapse
SS miliary TB?(6)
- Severe toxemia w dyspnea & cough
- Headache & rigidity
- Hepatosplenomegally
- Tachycardia
- Choroidal tubercules
- Few fine crepitations
Symptom post 1ry TB?(11)
- Asymp
- Tired & malaise
- Loss weight, appetite, night fever/sweat
- Cold
- Amenorhea
- Xsymp chest
- Persistent cough
- Expectoration(mucoid, purulent, bl stained)
- Hemoptysis
- Chest pain
- Wheeze & dyspnea
Sign pulmonary TB?(GE, chest exam, other sys)
- Xsign
- GE
- Pallor & cachexia
- Fever, inc HR & RR
- Clubbing(xcommon) - CE
- Xsign
- crepitation
- cavitation/fibrosis
- local/general wheezes
- consolidation, collapse/fibrosis - Other body system
Complication pul TB? (6)
- Bronchiectasis
- Aspergilloma (mycetoma)
- Massive hemoptysis
- Scar carcinoma
- ARDS(fulminant)
- Other organ
Haematogenous spread TB? (Intra/extrathoracic)
1. Intrathoracic lesion Pulmonary: -multiple TB cavity -miliary TB -TBma -Pleura, pericardium -lymph gland(hilar adenopathy) 2. Extrathoracic lesion -meninges(meningitis) -cns(tbma) -spine(Pott’s dis) -lymph node(tb lymphitis) -urogenital(urogenital tb) -serous membrane -joint(tb joint)
Ddx(4)
- Bronchial carcinoma
- Pneumonia
- Other coz hemoptysis
- Other coz prolonged fever/cough
Prognosis TB?
Proper management & compliance(high cure rate)
Extra pul TB? (9)
- Pleural
- LN
- Abd
- Pericarditis
- Bone & joint
- Genitourinary tract
- CNS
- Cutaneous
- Ocular
CP TB LN?(5)
- Neck, supraclavi, inguin, axil
- Fever
- Painless swell
- Gland discrete, firm, mobile then matted together
- Cold abscess/sinus
Inv TB LN?(3)
- ZN exam
- Culture(node biopsy, excise/fine needle aspiration)
- Excise LN biopsy
3 type abd TB?
- Tebes mesenterica(rt iliac fossa)
- Peritoneal tb(blstream)
- GIT tb(ileocecal & jejunoileum)
CP peritoneal tb? (4)
- Symp dev insidious
- Fever, weight loss
- Swell, pain, tenderness
- Diarrhea
CP GIT TB? (7)
- Fever & weight loss
- Pain & diarrhea
- Nausea & vomiting
- Rectal bleeding & melena
- Abd tenderness
- Mass(rt iliac fossa)
- Doughy abd
Comp git tb? (2)
- Psoas abscess w ulcer(skin)
2. Intestinal narrowing, obs & acute abd
Dx git tb? (5)
- CXR(past/present tb)
- US(thick loop of bowel, mesentric LN enlarge/hypoecho region(liver & spleen)
- CT abd
- Peritoneal fluid analysis
- Peritoneal biopsy
CP TB Pericarditis? (2)
- Symptom toxemia
2. SS pericardial effusion
Inv TB Pericarditis? (4)
- CXR(cardiomegaly, calcification)
- ECG(T wave inversion/flat)
- Echocardiography(pericardial effusion)
- Aspiration(bl stain/serous fluid)
CP bone & joint tb?
- Local radicular pain, stiffness & limit movement
- Abscess/sinus formation
- Toxemia
- Paraplegia
- Quadriplegia
- Gibbous deformity, kyphosis
Inv bone & joint tb? (3)
- Plain xray
- CT
- MRI
CP genitourinary tract tb?(7)
- Toxemia
- Freq, dysuria, lion pain, nocturia & hematuria
- Recurrent uti/pyuria
- Perineal sinuses
- Scrotal swell
- Renal tb
- Infertility, menorrhgia, amenorrhea, adenexial mass
Inv genitourinary tract tb? (4)
- Urine analysis
- IVP & renal us
- calcification, dilatate calyces - Renal biopsy
- Endometrial curetting