L1W3 Patho TB Flashcards
DefTB?
Chronic infective granuloma affecting nearly all body sys mainly lungs
Predisposing factors TB? (Enviromental/personal)
1) Environmental:
- Low socioeconomic
- Overcrowding
- Bad general hygiene
- Contact w tb pt
2) Personal factors:
- Negroes(more than white person) -Malnutrition
- Immune deficiency states
Causative agent(TB bacilli)?(char, structure, type)
Character
-Aerobic, Acid-fast, xmotile, xproduce exo/endotoxin, Carry by macrophages
Structure
-Carbohydrate, lipid, protein
Types
1) Human type(Mycobacterium tb) coz inf by inhalation
2) Bovine type(Mycobacterium Bovis) coz inf by ingestion
Methods of infection TB? (3)
1) Inhalation
2) Ingestion
3) Direct contact
Types TB? (1ry|2ry)
1ry|2ry
Young, ximmune | adulthood
Method inf:
Inha, ing, direct contact | endo/exogenous
Site:
lung, intes, tonsil, skin, nose | any site