L24 CNS

Question 1

What is the clinical manifestation of increased intacranial pressure?

Answer 1

1. Headache
2. Nausea
3. Papilloedema
4. Cerebral herniation

Question 2

What are the common clinical sequelae of CNS infection?

Answer 2

1. Meningitis
2. Encephalitis
3. Meningoencephalitis
4. Abscess

Question 3

What is the molecular findings in patient with glioblastoma?

Answer 3

Amplification of EGFR gene

Question 4

What is the consequence + example of having neurodegenerative disease in cerebral cortex region?

Answer 4

Dementia; Alzheimer

Question 5

What is the consequence + example of having neurodegenerative disease in basal ganglia and brainstem region?

Answer 5

Movement disorders; parkinsons

Question 6

3 types of herniation

Answer 6

1. Transtentorial herniation
2. Subfalcine herniation
3. Tonsillar herniation

Question 7

Where does the blood come from in epidural haematoma and subdural haematoma?

Answer 7

Epidural: Middle meningeal artery
Subdural: Venous origin

Question 8

What is a stroke?

Answer 8

Sudden, focal brain necrosis due to complete and prolonges ischemia

Question 9

2 types of stroke

Answer 9

1. Ischaemic
2. Haemorrhagic

Question 10

What are the clinical presentation of meningitis?

Answer 10

1. Headache
2. Fever
3. Neck stiffness
4. Photophobia

Question 11

What are the clinical presentations of brain abscess

Answer 11

1. Swinging fever
2. Raised ICP
3. Localising signs of CNS disease

Question 12

What is the histological features of glioblastoma?

Answer 12

1. Necrosis
2. Microvascular proliferation