L2 - Master regulators of Organ System Flashcards

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1
Q

Where is glucose secreted into?

A

pancreas

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2
Q

two main hormones responsible for maintaining glucose concentrations in the pancreas

A

insulin and glucagon

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3
Q

Two functional components of pancreas

A

exocrine component and endocrine component

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4
Q

Exocrine cells

A
  • produce enzymes to help with ingestion of food

- acinar cells and duct cells

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5
Q

Endocrine cells

A
  • consists of Islets of Langerhans (alpha cells, beta cells and delta cells)
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6
Q

Alpha cells

A

secrete glucagon

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7
Q

Beta cells

A

secrete insulin

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8
Q

Delta cells

A

secrete somatostatin

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9
Q

What occurs when there is low blood glucose levels?

A

low blood glucose levels signals the alpha cells in the pancreas to secrete glucagon which stimulates the liver to breakdown glycogen to glucose to secrete into the blood

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10
Q

What particular enzyme if required for the breakdown of glycogen to glucose?

A

glucose-6-phosphate

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11
Q

What occurs when there is high blood glucose levels?

A

high blood glucose levels signals the beta cells in the pancreas to secrete insulin which stimulates the fat cells to take up glucose from the blood causing the glucose levels in the blood cells to reach a normal level

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12
Q

Endocrine glands

A
  • groups of endocrine cells that are dedicated to a given function
  • hypothalamus, pituitary and pineal gland
  • thyroid gland
  • adrenal gland
  • pancreas
  • ovaries
  • testes
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13
Q

Hypothalamus

A
  • small neuroendocrine structure found just above brainstem
  • responsible for release of antidiuretic hormone (ADH) and oxytocin, and for the production of regulatory hormones via the pituitary gland
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14
Q

Antidiuretic hormone (ADH)

A

acts on kidneys to prevent fluid loss or water loss

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15
Q

Oxytcin

A

involved in the production of milk in females during lactation

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16
Q

Pituitary gland

A
  • hormone secreting gland which sits just below the hypothalamus
  • two parts: anterior pituitary gland and posterior pituitary gland
17
Q

Pineal gland

A
  • secretes melatonin which is responsible for the body clock
18
Q

Thyroid gland

A
  • responsible for metabolism (secretes T3 and T4)
  • lobes on thyroid glands are parathyroid glands (secretes parathyroid hormone, and regulates calcium and phosphate in the body)
19
Q

Pancreas

A
  • secretes insulin and glucagon
20
Q

what happens when you have diabetes

A

depleted insulin levels and therefore high blood glucose levels

21
Q

Adrenal glands

A
  • small, triangular-shaped glands located on top of both kidneys
  • made up of two parts: adrenal cortex (outer membrane) and adrenal medulla (inner)
22
Q

adrenal cortex

A

secretes cortisol (response for stress) and aldosterone (maintenance of K and Na)

23
Q

adrenal medulla

A

secretes adrenaline and noradrenaline (fight and flight response)

24
Q

Gonads

A

testes (androgens-testosterone) and ovaries (estrogen and progesterone)