L2: Epithelium Flashcards

1
Q

where is epithelia tissue found

A

body surfaces
lines hollow organs, cavities and ducts
forms glands of the body

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2
Q

key functions of epithelial tissue

A

selective barrier
secretory
protective

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3
Q

types of cell junctions

A

tight
adherens
desmosomes
hemidesmosomes
gap

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4
Q

composition of the cytoskeleton

A

microfilaments and intermediate filaments

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5
Q

function of microfilaments

A

strength
alter cell shape
link cytoplasm to membrane
tie cells together
muscle contraction

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6
Q

proteins involved in tight junctions

A

claudins and occludins

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7
Q

tight junctions are common in the

A

stomach
intestines
bladder

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8
Q

how do tight junctions maintain cell polarity

A

preventing migration of proteins between apical and basal surfaces

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9
Q

proteins involved in adherens junctions

A

cadherins and catenins

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10
Q

plaque layer in adherens junctions links what to what

A

actin to cadherins

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11
Q

function of adherens junctions

A

prevent cell separation from tension forces like in contractions

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12
Q

proteins involved in desmosome junctions

A

cadherins and desmoplakin

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13
Q

desmosome junctions link what to what

A

link cell surface to keratin

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14
Q

desmosome junctions are common in

A

skin epithelium and cardiac cells

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15
Q

function of desmosome junctions

A

resist shearing forces and bind muscle cells

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16
Q

proteins involved in gap junctions

A

6 connexIns make 1 connexOn

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17
Q

what size molecules do gap junctions allow through

A

up to 1kDa

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18
Q

function of hemidesmosome

A

connect epithelia to basement membrane
link keratin to basement membrane

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19
Q

proteins involved in hemidesmosomes

A

integrin
laminin
keratin

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20
Q

junctional complex

A

tight + adherens junctions + desmosome

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21
Q

composition of basement membrane

A

basal and reticular lamina

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22
Q

describe basal lamina

A

secreted by epithelial cells
contains collagen, laminin, proteoglycans and glycoproteins

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23
Q

describe reticular lamina

A

produced by fibroblasts in CT
contain fibrous proteins like collagen, fibronectin

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24
Q

function of basment membrane

A

support overlying epithelia
migratory surface for epithelia cells during growth and wound healing
physical barrier
filtration of substances in kidney

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25
in melanoma, the diameter is greater than ___
6mm
26
two types of epithelial tissue
covering and lining glandular
27
function of covering epithelia
cover exposed surfaces and internal cavities
28
transitional epithelium is found in the
bladder
29
simple squamous epithelium found where there is
diffusion filtration secretion where slippery surface needed
30
specialised subtypes of simple squamous epithelium
mesothelium endothelium
31
mesothelium lines
peritoneal, pleural and pericardial cavities
32
endothelium lines
inside of heart and blood and lymphatic vessels
33
simple cubodial epithelium is found where there is
secretion and absorption
34
subtypes of simple columnar epithelium
non-ciliated and ciliated
35
function of goblet cells
secrete mucous
36
non-ciliated simple columnar epithelium is found where there is
secretion, absorption and lubrication
37
ciliated simple columnar epithelium is found in
bronchioles fallopian tubes brain ventricles central canal of spinal cord sinuses
38
function of ciliated simple columnar epithelium
synchronous movements assist in motility of mucus and foreign objects and oocytes
39
specialised subtypes of stratified squamous epithelium
keratinised and non-keratanised
40
all forms of stratified squamous epithelium protect against
microbes
41
keratinised stratified squamous epithelium is found
where mechanical stress and dehydration are major issues ie. dry trauma areas
42
non-keratanised stratified squamous epithelium is found in
wet trauma areas
43
function of non-keratinised stratified squamous epithelium
protection from abrasion
44
pseudo-stratified columnar epithelium subtypes
ciliated and non-ciliated
45
stratified cubodial epithelium is found in
ducts of adult sweat glands oesophageal glands male urethra
46
stratified columnar epithelium is found in
part of urethra oesophageal glands anal mucosal membrane conjunctiva of eye
47
secretion pathway of endocrine glands
directly into blood via traversing interstitial fluid
48
secretion pathway of exocrine glands
into ducts that empty on surface of covering or lining epithelium
49
single cell exocrine glands
eg. mucous cells, goblet cells
50
simple gland
duct doesn't divide on way to gland cells
51
branched gland
several secretory areas share one duct
52
where are simple tubular glands
intestinal glands
53
where are simple coiled tubular glands found
merocrine sweat glands
54
where are simple branched tubular glands found
gastric glands mucous glands of oesophagus, tongue and duodenum
55
simple alveolar glands are
a stage in the embryonic development of simple branched glands
56
where are simple branched alveolar glands found
sebaceous glands
57
what makes a gland compound
duct divides one or more times on way to gland cells
58
where are compound tubular glands found
mucous glands in mouth bulbo-urethral glands seminiferous tubules of testes
59
where are compound alveolar glands found
mammary glands
60
where are compound tubuloalveolar glands found
salivary glands glands of resp. passage pancreas