L19: Antiarrhythmics

Question 1

Effective against both supraventricular and ventricular arrhythmias

Answer 1

Amiodarone

Question 2

Drug with NO torsade de pointes

Answer 2

Amiodarone

Question 3

Used for re-entrant supraventricular tachycardia

Answer 3

CCBs

Question 4

Sotalol is contraindicated in

Answer 4

asthma (B blocker)

Question 5

As CCBs, Verapamil and Diltiazem are only effective in…

Answer 5

the atria

Question 6

ACUTE Paroxysmal supra-ventricular (PSVT) treatment

Answer 6

IV drugs in order of preference:

1. Adenosine
2. Esomolol
3. CCBs

Question 7

Adverse effect: Yellowish-brown cornea and grayish-blue skin***

Answer 7

Amiodarone

Question 8

DOC for ventricular arrhythmias —> used in ACLS

Answer 8

Amiodarone

Question 9

Flecainide effect on effective refractory period

Answer 9

none

Question 10

CHRONIC Paroxysmal supra-ventricular (PSVT) treatment

Answer 10

in order of preference:

1. B blockers
2. CCBs

Question 11

What is the main side effect to worry about with Flecainide (Class IC)?

Answer 11

Strong pro-arrhythmic effect

Question 12

DOC for torsade de pointes

Answer 12

Magnesium

Question 13

Gene that causes slow acetylation

Answer 13

NAT2 gene (HIP drugs)

Question 14

Adverse effect: Thyroid dysfunction***

Answer 14

Amiodarone

Question 15

Marked effect on SA/AV nodes

Answer 15

CCBs

Question 16

Good for afib/flutter

Answer 16

CCBs (atria)

Question 17

The “P” in HIP drugs that cause SLE

Answer 17

Procainamide

Question 18

Quinidine syncope really means

Answer 18

torsade de pointes

Question 19

Adverse effect: Pulmonary fibrosis

Answer 19

Amiodarone

Question 20

DOC for acute ventricular arrhythmias

Answer 20

Lidocaine (Class IB)

Question 21

Lidocaine (Class IB) adverse effect

Answer 21

seizures

Question 22

Adverse effects of Quinidine (Class IA)

Answer 22

Low therapeutic index

Cardiac toxicity

Blocks alpha receptors

Paradoxical tachycardia

Torsade de pointes