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Pharm #2 > L17 Drugs > Flashcards

L17 Drugs Flashcards

1
Q

Nicotine

MOA:

Indication:

A

MOA: Activation of neuronal Nicotinic receptors

Indication: withdrawal symptoms of smoking cessation

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2
Q

Succinyllcholine

MOA:

Elimination:

Indication:

A

MOA: Depolarizing block of muscle nicotinic receptors

Elimination: Butyrl cholinesterase

Indication: Neuromuscular block for electroconvulsive shock therapy or emergency intubation

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3
Q

Acetylcholine

Half life:

MOA:

Elimination:

Indication:

A

Half life: ~150 msec

MOA: Nicotinic and muscarinic agonist

Elimination: AchE

Indication: NONE

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4
Q

Methacholine

MOA:

Indication:

A

MOA: Muscarinic agonist

Indication: Diagnosis of subclinical asthma, or test for severity of asthma

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5
Q

Carbachol

MOA:

Indication:

A

MOA: Muscarinic and nicotinic receptor agonist

Indication: miotic agent in ocular surgery, to reduce pressure following ocular surgery

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6
Q

Bethanechol

MOA:

Indication:

A

MOA: muscarinic agonist

Indication: urinary retention, bladder atony

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7
Q

Pilocarpine

Half-life

MOA:

Indication:

A

half-life: ~1 hour

MOA: muscarinic agonist

Indication: dry mouth from head and neck radiation, narrow angle glaucoma

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8
Q

Neostigmine

MOA:

Indication:

A

MOA: AchE inhibitor

Indication: Myasthenia gravis, reverse neuromuscular block

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9
Q

Edrophonium

half-life:

MOA:

Indication:

A

half-life: ~10 min

MOA: AchE inhibitor

Indication: diag of myasthenia gravis, reversal of neuromuscular block

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10
Q

Physostigmine

MOA:

Indication:

A

MOA: Reversible AchE inhibitor

Indication: Delirium from anticholinergic drugs, glaucoma

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11
Q

Donepezil

MOA:

Indication:

A

MOA: reversible AchE inhibitor

Indication: Alzhimer’s dx.

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12
Q

Pralidoxime

half-life:

MOA:

Indication:

A

half-life: ~75 min

MOA: peripheral AchE reactivator

Indication: Respiratory muscle weakness in organophosphate poisoning

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13
Q

Echothiophate

half-life

MOA:

Indication:

A

half-life: very long

MOA: irreversible AchE inhibitor

Indication: open angle glaucoma

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14
Q

Atropine

MOA:

Indication:

A

MOA: muscarinic antagonist

Indication: excess secretions during surgery, the increased freq and urg. associated with cystitis, hypertonic gut, organophosphate poisoning, bradycardia

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15
Q

Scopolamine

MOA:

Indication:

A

MOA: Muscarinic antagonist

Indication: motion sickness, anti-salilagogue in surgery

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16
Q

Gylcopyrrolate

MOA:

Indication:

A

MOA: muscarinic receptor antagonist

Indication: protects against excessive muscarinic activation during reversal of neuromuscular blockade, anti-salilagogue

Pharm #2 (13 decks)

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