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Pharm #2 > L14-16 drugs > Flashcards

L14-16 drugs Flashcards

1
Q

Epinephrine

Half life:

MOA:

Elimination:

Indication:

A

Half life: short
MOA: a and B agonist
Elimination: COMT-urine
Indication: Anaphylaxis, shock, cardiac arrest, and heart block

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2
Q

Norepinephrine

Half life:

MOA:

Elimination:

Indication:

A

Half life: short

MOA: a- agonist, B1- agonist

Elimination: MOA and COMT- urine

Indication: Acute hypotension due to shock

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3
Q

Dopamine

Half life:

MOA:

Elimination:

Indication:

A

Half life: ~2 minutes

MOA: B-agonist, some a- agonist activity

Elimination: MAO and COMT- urine

Indication: Cardiogenic shock

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4
Q

Isoproterenol

Half life:

MOA:

Elimination:

Indication:

A

Half life: Short

MOA: B-agonist (non-selective)

Elimination: COMT- urine

Indication: Transient Heart block

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5
Q

Dobutamine

Half life:

MOA:

Elimination:

Indication:

A

Half life: 2-3 minutes

MOA: B1- agonist

Elimination: COMT- urine (rapid)

Indication: Short term Rx for low cardiac contractility (cardia insufficiency and cadiogenic shock)

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6
Q

Terbutaline

MOA:

Indication:

A

MOA: B2- agonist

Indication: Prevent and reverse bronchospasm in asthma, bronchitis and emphysema

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7
Q

Albuterol
MOA:

Indication:

A

MOA: B2-agonist

Indication: Bronchial SM relaxation

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8
Q

Phenylephrine

half-life:

MOA:

Indication:

A

half-life: less than 1 hr

MAO: A1 agonist

indications: pressor agent for anesthesia, nasal congestion, dilate pupil

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9
Q

clonidine

MOA:

Indication:

A

MOA: a2-agonist

Indication: hypertension

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10
Q

Amphetamine

MOA:

Indication:

A

MOA: Indirect sympathomimetic

Indication: ADHD

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11
Q

Methylphenidate

MOA:

Indication:

A

MOA: indirect sympathomimetic

Indication: ADHD

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12
Q

Ephedrine

MOA:

Indication:

A

MOA: indirect sympathomimetic

Indication: Pressor agent with anesth.

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13
Q

Methylphenidate

MOA:

Indication:

A

MOA: Indirect sympathomimetic

Indication: ADHD

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14
Q

pseudo-ephedrine

MOA:

Indication:

A

MOA: indirect sympathomimetic

Indication: nasal decongestion

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15
Q

Tyramine

Half-life:

MOA:

Elimination:

Indication:

A

half-life: normally very short

MOA: displaces NE

elimination: MAO

Indication: not therapeutic

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16
Q

Propranolol

Half-life:

MOA:

Indication:

A

Half-life: 4 hrs

MOA: B-Blocker

Indication: Hypertension, angina due to atherosclerosis, MI

17
Q

Timolol

Half-life:

MOA:

Indication:

A

Half-life: 4 hours

MOA: B-blocker

Indication: glaucoma

18
Q

Nadolol

Half-life:

MOA:

Indication:

A

Half-life: 20-24 hours

MOA: B-blocker

Indication: long-term angina, hypertension

19
Q

Atenolol

MOA:

Indication:

A

MOA: B1-blocker

Indication: hypertension, angina, MI

20
Q

Metoprolol

MOA:

Indication:

A

MOA: B1-antagonist

Indication: hypertension, long-term angina rx

21
Q

Pindolol

MOA:

Indication:

A

MOA: B-antagonist (w/ partial agonist activity)

Indication: hypertension

22
Q

Esmolol

Half-life:

MOA:

Indication:

A

half-life: ~9 min

MOA: B1-Blocker

Indication: Supra-ventricular tachycardia

23
Q

Pheonxy-benzamine

MOA:

Indication:

A

MOA: a-blocker

Indication: pheochromo-cytoma

24
Q

Doxazonsin

MOA:

A

MOA: A1-antagonist

25
Q

Terazosin

MOA:

Indication:

A

MOA: a1-blocker

Indication: Prostatic hyperplasia, hypertension

Pharm #2 (13 decks)

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