L16-peripheral lung disease Flashcards

1
Q

what components of ventilation or respiration is chnaged whenthere is a respiratory disease

A

compliance

airway R

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2
Q

eqn for ventilation

A

Pb-Pa/AW R

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3
Q

egs od peripheral lung disease

A

asthma
chronic obstructive pulm diesease 9#COPD
-fibrosis

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4
Q

symtopms of asthma

A

airway inflamm
airway obstruction
bronchoconstriction
cough

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5
Q

what is decreased during asthma

A

alveolar ventilation
partial pressure gradients for diffusion
AW diameter reduced

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6
Q

NR of FEV1:FVC

A

~0.8

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7
Q

what is FEV1

A

how much literes of air in 1 sec

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8
Q

value fo FEV1:FVC in asthma and why

A
  1. 25

- lower intake of o2 due to severe obstruction

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9
Q

treatment for astham

A

reliever - bronchodilators to redeuce R

preventer- anti inflamm drugs

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10
Q

classes of relievers

A

beta 2 agonists
theophyllines - increase SNS in SM
anti muscarinics - blocking PNS

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11
Q

classes of preventers

A

steriods - counteract airway inflamm

leukotriene receptor antagonist - blocks bronchocntriction

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12
Q

symtopms and patholgy features of COPD

A
loss of alvelo and its recoil > collapse
-AW obstruction 
air trapping 
-hyperinflation 
inflamm
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13
Q

what is emphysema

A

shortness of breath due to the collapse or damage of alveoli

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14
Q

what ahhepnds to the total system compliancce due to emphysema

A

increases due to increease lung complaince

- increases FRC (less air to ventilate)

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15
Q

classififation of COPD based FEV1

A

mild, moderate and severe

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16
Q

NR for Mild FEV1 for COPD

A

50-80%

17
Q

NR for moderate FEV1 for COPD

A

30-49%

18
Q

NR for severe FEV1 for COPD

A

less than 30%

19
Q

what chnages in the flow volume loop for COPD

A

decreased
PEF
ERV
IRV

increased
FRC
RV

20
Q

management for COPD

A

bronchdilators
rehab
long term O2 therapy

21
Q

what is fibrosis

A

he development of fibrous connective tissue as a reparative response to injury or damage.

22
Q

causes of fibrosis

A

environment, systemic diseases, drugs side effects

23
Q

symptoms of fibrosis

A

dyspoea - breathlessness
dry cough
lung crackes

24
Q

features of fibrosis that is increases or decreases

A
increased:
fibroblast prolif
elastin and collagen secreted
thickening of alveoli
thickness of diffusion barrier 

decreased lung complaince

25
Q

fibrosis on total system complaince

A

decreased due to decrease lung compliance

26
Q

fibrosis on FEV1-FVC

A

no change as the ratio is the same but the VC is decrease

27
Q

fibrosis on features of flow-vol loop

A
decreased
PEF
ERV
IRV
TLC
VC
FRC
RV