L16-peripheral lung disease Flashcards
what components of ventilation or respiration is chnaged whenthere is a respiratory disease
compliance
airway R
eqn for ventilation
Pb-Pa/AW R
egs od peripheral lung disease
asthma
chronic obstructive pulm diesease 9#COPD
-fibrosis
symtopms of asthma
airway inflamm
airway obstruction
bronchoconstriction
cough
what is decreased during asthma
alveolar ventilation
partial pressure gradients for diffusion
AW diameter reduced
NR of FEV1:FVC
~0.8
what is FEV1
how much literes of air in 1 sec
value fo FEV1:FVC in asthma and why
- 25
- lower intake of o2 due to severe obstruction
treatment for astham
reliever - bronchodilators to redeuce R
preventer- anti inflamm drugs
classes of relievers
beta 2 agonists
theophyllines - increase SNS in SM
anti muscarinics - blocking PNS
classes of preventers
steriods - counteract airway inflamm
leukotriene receptor antagonist - blocks bronchocntriction
symtopms and patholgy features of COPD
loss of alvelo and its recoil > collapse -AW obstruction air trapping -hyperinflation inflamm
what is emphysema
shortness of breath due to the collapse or damage of alveoli
what ahhepnds to the total system compliancce due to emphysema
increases due to increease lung complaince
- increases FRC (less air to ventilate)
classififation of COPD based FEV1
mild, moderate and severe
NR for Mild FEV1 for COPD
50-80%
NR for moderate FEV1 for COPD
30-49%
NR for severe FEV1 for COPD
less than 30%
what chnages in the flow volume loop for COPD
decreased
PEF
ERV
IRV
increased
FRC
RV
management for COPD
bronchdilators
rehab
long term O2 therapy
what is fibrosis
he development of fibrous connective tissue as a reparative response to injury or damage.
causes of fibrosis
environment, systemic diseases, drugs side effects
symptoms of fibrosis
dyspoea - breathlessness
dry cough
lung crackes
features of fibrosis that is increases or decreases
increased: fibroblast prolif elastin and collagen secreted thickening of alveoli thickness of diffusion barrier
decreased lung complaince
