L10 by uni - heart failure 2

Question 1

how can drugs affect the Heart function

Answer 1

directly - force of coontraction or rate of rhythm

indirectly - blood vessels, blood vol

Question 2

classes do drugs to treat heart failure

Answer 2

vasodilators
cardioinhibitory
duiretics
ionotrpoic - effect on contractily

Question 3

fiest line therapy for HRrEF

Answer 3

ACE inhibitors, B-blockers, diuertics

Question 4

role of beta blockers drugs

Answer 4

• bind to beta receptors so block NA and Adr
• reduce SNS activity
• ionotropy decreases for patients with systolic dysfunction

Question 5

role of angiotensin converting enzyme (ACE) inhibitors

Answer 5

• inhibits production of angiotensin 2 so vasodilation is causes to decrease BP

Question 6

role of angiotensin receptors blockers (ARB) for heart failure

Answer 6

blocks angio 1 so the heart muscle relaxes more

Question 7

role fo diuetrics and types of it

Answer 7

• increase urine output by excreting more sodium to decrease BP
• loop diu
• thaizide
• potassium sparing diueteics

Question 8

second line therapy for HRrEF

Answer 8

digitialis
entresto
ivabradine

Question 9

role of digitialis as a drug fro hf

Answer 9

inhibit NA K pump to increase intra Na conc

-increase contracility

Question 10

role of ivabradine

Answer 10

• reduces the Na current during the depol phase

- reduces HR

Question 11

role of nitrodilators

Answer 11

• release NO

- increase vasodil