L14-15 PHRM20001 - Drug discovery then & now

Question 1

4 ways of drug discovery back then

Answer 1

1) Observation/experience
2) Serendipity
3) Screening
4) Synthetic chemistry

Question 2

Toxicity - 4 types

Answer 2

1) Acute (effects of a single exposure)
2) Chronic (6-24 months of long term exposure)
3) Mutagenicity/carcinogenicity (cancerous)
4) Reproductive (effects on foetus/gonads)