L13 - Imaging the brain (HM) Flashcards
What is the principle of computerised tomography (CT)
uses x-rays to create images of the brain
x-ray absorption varies by tissue density - denser tissue absorbs more x-rays
images are constructed form x-ray scans taken from multiple angles
What are CT scans used for?
diagnoses diseases. or. injuries (e.g., internal bleeding)
typically not used in research due to lower spatial resolution
involves small amounts of radiation
What is the principle of Magnetic Resonance Imaging?
based on the behaviour of hydrogen atoms in a magnetic field
strong magnets align hydrogen protons, and radiation waves alter their orientation
the MRI signal is generated as protons return to their aligned state
what to Functional Magnetic Resonance imaging (fMRI) do?
Measures BOLD signal to infer brain activity.
High spatial resolution, poor temporal resolution.
what do Functional Near-Infrared Spectroscopy (fNIRS) do?
Measures blood oxygenation through optical absorption.
Good temporal resolution, limited spatial resolution.
What do PET scans do?
Measures biochemical changes using radioactive tracers.
Moderate temporal and spatial resolution; detects diseases and conditions early.